Combining multiple family-based association studies (2007)
Tang, Hua, Peng, Jie, Wang, Pei, Coram, Marc, Hsu, Li
Abstract While high-throughput genotyping technologies are becoming readily available, the merit of using these technologies to perform genome-wide association studies has not been established. One...
Peng, Jie, Wang, Pei, Tang, Hua
Abstract In the fast-developing field of expression quantitative traits loci (eQTL) studies, much interest has been concentrated on detecting genomic regions containing transcriptional regulators...
Estimation of the allele frequency at genetic markers is a key ingredient in biological and biomedical research, such as studies of human genetic variation or of the genetic etiology of heritable...
Tang, Hua, Wei, Ying, Doboli, Alex
This paper proposes a novel architecture synthesis algorithm for single-loop single-bit ?S modulators. We defined a generic modulator architecture and derived its noise and signal transfer function...
Tang, Hua, Wei, Ying, Doboli, Alex
This paper proposes a novel architecture synthesis algorithm for single-loop single-bit ?S modulators. We defined a generic modulator architecture and derived its noise and signal transfer function...
Reduced selection leads to accelerated gene loss in Shigella (2007)
Hershberg, Ruth, Tang, Hua, Petrov, Dmitri A
Abstract Background Obligate pathogenic bacteria lose more genes relative to facultative pathogens, which, in turn, lose more genes than free-living bacteria. It was suggested that the increased gene...
Complementarity in a macroscopic observation (2007)
Cao, De-Zhong, Xiong, Jun, Tang, Hua, Lin, Lu-Fang, Zhang, Su-Heng, Wang, Kaige
Complementarity is usually considered as a phenomenon of microscopic systems. In this paper we report an experimental observation of complementarity in the correlated double-slit interference with a...
Locally weighted transmission/disequilibrium test for genetic association analysis (2005)
Hsu, Li, Yu, Xuesong, Houwing-Duistermaat, Jeanine J, Uh, Hae-Won, El Galta, Rachid, Lebrec, Jeremie JP, ...
Abstract The transmission/disequilibrium test statistic has been used for assessing genetic association in affected-parent trios. In the presence of multiple tightly linked marker loci where local...
Ethnicity and Human Genetic Linkage Maps (2005)
Jorgenson, Eric, Tang, Hua, Gadde, Maya, Province, Mike, Leppert, Mark, Kardia, Sharon, ...
Human genetic linkage maps are based on rates of recombination across the genome. These rates in humans vary by the sex of the parent from whom alleles are inherited, by chromosomal position, and by...
Tang, Hua, Quertermous, Tom, Rodriguez, Beatriz, Kardia, Sharon LR, Zhu, Xiaofeng, Brown, Andrew, ...
We have analyzed genetic data for 326 microsatellite markers that were typed uniformly in a large multiethnic population-based sample of individuals as part of a study of the genetics of hypertension...
Thesis (Ph. D.)--Stony Brook University, 2005.
Some rules in protein evolution / (2005)
Thesis (Ph. D.)--University of Chicago, Dept. of Ecology and Evolution, June 2005.
Categorization of humans in biomedical research: genes, race and disease (2002)
Risch, Neil, Burchard, Esteban, Ziv, Elad, Tang, Hua
Abstract A debate has arisen regarding the validity of racial/ethnic categories for biomedical and genetic research. Some claim 'no biological basis for race' while others advocate a 'race-neutral'...
Categorization of humans in biomedical research: genes, race and disease (2002)
Risch, Neil, Burchard, Esteban, Ziv, Elad, Tang, Hua
A debate has arisen regarding the validity of racial/ethnic categories for biomedical and genetic research. Some claim ‘no biological basis for race’ while others advocate a ‘race-neutral’...
Statistical methods for two problems in DNA sequence comparisons / (2002)
Tang, Hua., Siegmund, David O. Advisor
Submitted to the Department of Statistics.
Three essays on continuous time finance (2001)
In first essay, I present a general equilibrium model of financial asset pricing where market can be incomplete. The focus is on the effects of economics fundamentals on capital asset pricing model....
Thesis (Ph. D.)--Dept. of Biology, University of Utah, 1996.
The Raman diagnostics and process physics of laser-induced surface modifications /--Hua Tang. (1992)
Department: Applied Physics.
Thesis (Ph. D.)--Columbia University, 1992.
Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors
Levanon, Ditsa, Goldstein, Robert E., Bernstein, Yael, Tang, Hua, Goldenberg, Dalia, Stifani, Stefano, ...
The mammalian AML/CBFα runt domain (RD) transcription factors regulate hematopoiesis and osteoblast differentiation. Like their Drosophila counterparts, most mammalian RD proteins terminate in a...
Tang, Hua, Hornstein, Eran, Stolovich, Miri, Levy, Galit, Livingstone, Mark, Templeton, Dennis, ...
Vertebrate TOP mRNAs contain an oligopyrimidine tract at their 5′ termini (5′TOP) and encode components of the translational machinery. Previously it has been shown that they are subject to...
Stolovich, Miri, Tang, Hua, Hornstein, Eran, Levy, Galit, Cohen, Ruth, Bae, Sun Sik, ...
Translation of terminal oligopyrimidine tract (TOP) mRNAs, which encode multiple components of the protein synthesis machinery, is known to be controlled by mitogenic stimuli. We now show that the...
Categorization of humans in biomedical research: genes, race and disease
Risch, Neil, Burchard, Esteban, Ziv, Elad, Tang, Hua
A debate has arisen regarding the validity of racial/ethnic categories for biomedical and genetic research. An epidemiologic perspective on the issue of human categorization in biomedical and genetic...
Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways
Schuurmans, Carol, Armant, Olivier, Nieto, Marta, Stenman, Jan M, Britz, Olivier, Klenin, Natalia, ...
Neocortical projection neurons, which segregate into six cortical layers according to their birthdate, have diverse morphologies, axonal projections and molecular profiles, yet they share a common...
Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human
Song, Huai-Dong, Tu, Chang-Chun, Zhang, Guo-Wei, Wang, Sheng-Yue, Zheng, Kui, Lei, Lian-Cheng, ...
The genomic sequences of severe acute respiratory syndrome coronaviruses from human and palm civet of the 2003/2004 outbreak in the city of Guangzhou, China, were nearly identical. Phylogenetic...
Qian, Wei, Jia, Yantao, Ren, Shuang-Xi, He, Yong-Qiang, Feng, Jia-Xun, Lu, Ling-Feng, ...
Xanthomonas campestris pathovar campestris (Xcc) is the causative agent of crucifer black rot disease, which causes severe losses in agricultural yield world-wide. This bacterium is a model organism...
Tang, Hua, Siegmund, David O, Shen, Peidong, Oefner, Peter J, Feldman, Marcus W
This article proposes a method of estimating the time to the most recent common ancestor (TMRCA) of a sample of DNA sequences. The method is based on the molecular clock hypothesis, but avoids...
Genomewide Evolutionary Rates in Laboratory and Wild Yeast
Ronald, James, Tang, Hua, Brem, Rachel B.
As wild organisms adapt to the laboratory environment, they become less relevant as biological models. It has been suggested that a commonly used S. cerevisiae strain has rapidly accumulated...
Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors
Levanon, Ditsa, Goldstein, Robert E., Bernstein, Yael, Tang, Hua, Goldenberg, Dalia, Stifani, Stefano, ...
The mammalian AML/CBFα runt domain (RD) transcription factors regulate hematopoiesis and osteoblast differentiation. Like their Drosophila counterparts, most mammalian RD proteins terminate in a...
Tang, Hua, Hornstein, Eran, Stolovich, Miri, Levy, Galit, Livingstone, Mark, Templeton, Dennis, ...
Vertebrate TOP mRNAs contain an oligopyrimidine tract at their 5′ termini (5′TOP) and encode components of the translational machinery. Previously it has been shown that they are subject to...
Stolovich, Miri, Tang, Hua, Hornstein, Eran, Levy, Galit, Cohen, Ruth, Bae, Sun Sik, ...
Translation of terminal oligopyrimidine tract (TOP) mRNAs, which encode multiple components of the protein synthesis machinery, is known to be controlled by mitogenic stimuli. We now show that the...
Categorization of humans in biomedical research: genes, race and disease
Risch, Neil, Burchard, Esteban, Ziv, Elad, Tang, Hua
A debate has arisen regarding the validity of racial/ethnic categories for biomedical and genetic research. An epidemiologic perspective on the issue of human categorization in biomedical and genetic...
Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways
Schuurmans, Carol, Armant, Olivier, Nieto, Marta, Stenman, Jan M, Britz, Olivier, Klenin, Natalia, ...
Neocortical projection neurons, which segregate into six cortical layers according to their birthdate, have diverse morphologies, axonal projections and molecular profiles, yet they share a common...
Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human
Song, Huai-Dong, Tu, Chang-Chun, Zhang, Guo-Wei, Wang, Sheng-Yue, Zheng, Kui, Lei, Lian-Cheng, ...
The genomic sequences of severe acute respiratory syndrome coronaviruses from human and palm civet of the 2003/2004 outbreak in the city of Guangzhou, China, were nearly identical. Phylogenetic...
Qian, Wei, Jia, Yantao, Ren, Shuang-Xi, He, Yong-Qiang, Feng, Jia-Xun, Lu, Ling-Feng, ...
Xanthomonas campestris pathovar campestris (Xcc) is the causative agent of crucifer black rot disease, which causes severe losses in agricultural yield world-wide. This bacterium is a model organism...
Risch, Neil, Tang, Hua, Katzenstein, Howard, Ekstein, Josef
The presence of four lysosomal storage diseases (LSDs) at increased frequency in the Ashkenazi Jewish population has suggested to many the operation of natural selection (carrier advantage) as the...
Tang, Hua, Quertermous, Tom, Rodriguez, Beatriz, Kardia, Sharon L. R., Zhu, Xiaofeng, Brown, Andrew, ...
We have analyzed genetic data for 326 microsatellite markers that were typed uniformly in a large multiethnic population-based sample of individuals as part of a study of the genetics of hypertension...
Ethnicity and Human Genetic Linkage Maps
Jorgenson, Eric, Tang, Hua, Gadde, Maya, Province, Mike, Leppert, Mark, Kardia, Sharon, ...
Human genetic linkage maps are based on rates of recombination across the genome. These rates in humans vary by the sex of the parent from whom alleles are inherited, by chromosomal position, and by...
Tang, Hua, Siegmund, David O, Shen, Peidong, Oefner, Peter J, Feldman, Marcus W
This article proposes a method of estimating the time to the most recent common ancestor (TMRCA) of a sample of DNA sequences. The method is based on the molecular clock hypothesis, but avoids...
Genomewide Evolutionary Rates in Laboratory and Wild Yeast
Ronald, James, Tang, Hua, Brem, Rachel B.
As wild organisms adapt to the laboratory environment, they become less relevant as biological models. It has been suggested that a commonly used S. cerevisiae strain has rapidly accumulated...
Reconstructing Genetic Ancestry Blocks in Admixed Individuals
Tang, Hua, Coram, Marc, Wang, Pei, Zhu, Xiaofeng, Risch, Neil
A chromosome in an individual of recently admixed ancestry resembles a mosaic of chromosomal segments, or ancestry blocks, each derived from a particular ancestral population. We consider the problem...
Gojobori, Jun, Tang, Hua, Akey, Joshua M., Wu, Chung-I
The selective forces acting on amino acid substitutions may be different in the two phases of molecular evolution: polymorphism and fixation. Negative selection and genetic drift may dominate the...
Controlling for false positive findings of trans-hubs in expression quantitative trait loci mapping
Peng, Jie, Wang, Pei, Tang, Hua
In the fast-developing field of expression quantitative traits loci (eQTL) studies, much interest has been concentrated on detecting genomic regions containing transcriptional regulators that...
Combining multiple family-based association studies
Tang, Hua, Peng, Jie, Wang, Pei, Coram, Marc, Hsu, Li
While high-throughput genotyping technologies are becoming readily available, the merit of using these technologies to perform genome-wide association studies has not been established. One major...
Reduced selection leads to accelerated gene loss in Shigella
Hershberg, Ruth, Tang, Hua, Petrov, Dmitri A
The rate of gene loss was studied in the facultative pathogens, E. coli and Shigella, and was found to be greater in the more niche-limited Shigella. This is demonstrated to be due to a genome-wide...