Hsiou-Chi Liou

NF-kB inhibitor blocks B cell development at two checkpoints (2004)

Feng, Biao, Cheng, Shuhua, Pear, Warren S, Liou, Hsiou-Chi

Abstract Members of the NF-kB transcription factor family are differentially expressed in the B cell lineage. Disruption of individual or two NF-kB subunits exhibits distinct defects in B lymphocyte...

Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages (2000)

Sanjabi, Shomyseh, Hoffmann, Alexander, Liou, Hsiou-Chi, Baltimore, David, Smale, Stephen T.

A major challenge in the study of gene regulation by NF-kappaB/Rel transcription factors is to understand, at the biological and mechanistic levels, the selective functions of individual Rel family...

Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiation (1994)

Liou, Hsiou-Chi, Sha, William C., Scott, Martin L., Baltimore, David

The NF-kappa B/Rel family of at least five transcription factor polypeptides is thought to function both as a developmental regulator in B cells and as a rapid response system in all cells. To...

The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner (1993)

Nolan, Garry P., Fujita, Takashi, Bhatia, Kishor, Huppi, Conrad, Liou, Hsiou-Chi, Scott, Martin L., ...

The product of the putative proto-oncogene bcl-3 is an I kappa B-like molecule with novel binding properties specific for a subset of the rel family of transcriptional regulators. In vitro, Bcl-3...

Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages

Sanjabi, Shomyseh, Hoffmann, Alexander, Liou, Hsiou-Chi, Baltimore, David, Smale, Stephen T.

A major challenge in the study of gene regulation by NF-κB/Rel transcription factors is to understand, at the biological and mechanistic levels, the selective functions of individual Rel family...

Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation

Hilliard, Brendan A., Mason, Nicola, Xu, Lingyun, Sun, Jing, Lamhamedi-Cherradi, Salah-Eddine, Liou, Hsiou-Chi, ...

Different members of the Rel/NF-κB family may play different roles in immunity and inflammation. We report here that c-Rel–deficient mice are resistant to autoimmune encephalomyelitis and are...

NF-kB inhibitor blocks B cell development at two checkpoints

Feng, Biao, Cheng, Shuhua, Pear, Warren S, Liou, Hsiou-Chi

Members of the NF-kB transcription factor family are differentially expressed in the B cell lineage. Disruption of individual or two NF-kB subunits exhibits distinct defects in B lymphocyte...

Homeostatic cell-cycle control by BLyS: Induction of cell-cycle entry but not G1/S transition in opposition to p18INK4c and p27Kip1

Huang, Xiangao, Di Liberto, Maurizio, Cunningham, Adam F., Kang, Lin, Cheng, Shuhua, Ely, Scott, ...

Cell-cycle entry is critical for homeostatic control in physiologic response of higher organisms but is not well understood. The antibody response begins with induction of naïve mature B cells,...

Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages

Sanjabi, Shomyseh, Hoffmann, Alexander, Liou, Hsiou-Chi, Baltimore, David, Smale, Stephen T.

A major challenge in the study of gene regulation by NF-κB/Rel transcription factors is to understand, at the biological and mechanistic levels, the selective functions of individual Rel family...

Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation

Hilliard, Brendan A., Mason, Nicola, Xu, Lingyun, Sun, Jing, Lamhamedi-Cherradi, Salah-Eddine, Liou, Hsiou-Chi, ...

Different members of the Rel/NF-κB family may play different roles in immunity and inflammation. We report here that c-Rel–deficient mice are resistant to autoimmune encephalomyelitis and are...

NF-kB inhibitor blocks B cell development at two checkpoints

Feng, Biao, Cheng, Shuhua, Pear, Warren S, Liou, Hsiou-Chi

Members of the NF-kB transcription factor family are differentially expressed in the B cell lineage. Disruption of individual or two NF-kB subunits exhibits distinct defects in B lymphocyte...

Homeostatic cell-cycle control by BLyS: Induction of cell-cycle entry but not G1/S transition in opposition to p18INK4c and p27Kip1

Huang, Xiangao, Di Liberto, Maurizio, Cunningham, Adam F., Kang, Lin, Cheng, Shuhua, Ely, Scott, ...

Cell-cycle entry is critical for homeostatic control in physiologic response of higher organisms but is not well understood. The antibody response begins with induction of naïve mature B cells,...

Nuclear Factor κb Is Required for the Development of Marginal Zone B Lymphocytes

Cariappa, Annaiah, Liou, Hsiou-Chi, Horwitz, Bruce H., Pillai, Shiv

Although immunoglobulin (Ig)MhiIgDlo/−CD21hi marginal zone B cells represent a significant proportion of naive peripheral splenic B lymphocytes, few of the genes that regulate their development...