A Comparison of Some Robust Procedures for Estimating a Linear Discriminant Function, (9999)
A number of methods have been suggested for robustly estimating a linear discriminant function. These include substitution of robust estimates for the mean and covariance matrix and methods which...
Hongzhe Li, Ninning Liu, Grace K. Rajendran, Thomas J. Gernon, Jason K. Rockhill, Jeffrey L. Schwartz, ...
Li, H., Liu, N., Rajendran, G. K., Gernon, T. J., Rockhill, J. K., Schwartz, J. L. and Gu, Y. A Role for Endogenous and Radiation-Induced DNA Double-Strand Breaks in p53-Dependent Apoptosis during...
Microarray time course (MTC) gene expression data are commonly collected to study the dynamic nature of biological processes. One important problem is to identify genes that show different expression...
Li, Hongzhe, Rajendran, Grace K, Liu, Ninning, Ware, Carol, Rubin, Brian P, Gu, Yansong
Abstract Introduction Estrogen and insulin-like growth factor-1 (IGF-1) play important roles in mammary gland development and breast cancer. SirT1 is a highly conserved protein deacetylase that can...
Time course studies of gene expression are essential in biomedical research to understand biological phenomena that evolve in a temporal fashion. Microarray technology makes it possible to study...
Partial Cox Regression Analysis for High-Dimensional Microarray Gene Expression Data (2004)
An important application of microarray technology is to predict various clinical phenotypes based on the gene expression profile. Success has been demonstrated in molecular classification of cancer...
An important application of microarray technology is to relate gene expression profiles to various clinical phenotypes of patients. Success has been demonstrated in molecular classification of cancer...
Dimension Reduction Methods for Microarrays with Application to Censored Survival Data (2004)
Recent research has shown that gene expression profiles can potentially be used for predicting phenotypes such as cancer types and survival time in biomedical research. Microarray technology which...
A Hidden Markov Modeling Approach for Admixture Mapping Based on Case-Control Haplotype Data (2003)
Zhang, Chun, Chen, Kun, Seldin, Michael F, Li, Hongzhe
Admixture mapping is potentially a powerful method for mapping genes for complex human diseases, when the disease frequency due to a particular disease susceptible gene is different between founding...
The additive genetic gamma frailty model has been proposed for genetic linkage analysis for complex diseases to account for variable age of onset and possible covariates effects. To avoid...
Responses of inferior colliculus neurons to sinusoidal amplitude modulation in chinchillas / (2003)
Thesis (Ph. D.)--Arizona State University, 2003.
Complex human diseases are often due to multiple disease genes with variable age of onset, as well as both genetic and environmental risk factors. In order to simultaneously consider two possible...
Complex human diseases are often due to multiple disease genes with variable age of onset, as well as both genetic and environmental risk factors. In order to simultaneously consider two possible...
Complex human diseases are often due to multiple disease genes with variable age of onset, as well as both genetic and environmental risk factors. In order to simultaneously consider two possible...
Complex human diseases are often due to multiple disease genes with variable age of onset, as well as both genetic and environmental risk factors. In order to simultaneously consider two possible...
Kernel Cox Regression Models For Linking Gene (2002)
this paper is to develop new statistical methods for relating gene expression profiles to censored survival data such as time to cancer recurrence or death. From the statistical point of view, one...
Cluster-Rasch models for microarray gene expression data (2001)
Abstract Background We propose two different formulations of the Rasch statistical models to the problem of relating gene expression profiles to the phenotypes. One formulation allows us to...
Computing the Cox Model for Case Cohort Designs (2000)
Prentice #9# proposed a case-cohort design as an e#cient subsampling mechanism for survival studies. Several other authors have expanded on these ideas to create a family of related sampling plans,...
Seldin, Michael F., Morii, Takanobu, Collins-Schramm, Heather E., Chima, Bill, Kittles, Rick, Criswell, Lindsey A., ...
Theoretically, markers that distinguish European from West African ancestry can be used to examine the origin of chromosomal segments in individual African Americans. In this study, putative...
AAA ATPases regulate membrane association of yeast oxysterol binding proteins and sterol metabolism
Wang, Penghua, Zhang, Yong, Li, Hongzhe, Chieu, Hai Kee, Munn, Alan L, Yang, Hongyuan
The yeast genome encodes seven oxysterol binding protein homologs, Osh1p–Osh7p, which have been implicated in regulating intracellular lipid and vesicular transport. Here, we show that both Osh6p...
Ethnic-Difference Markers for Use in Mapping by Admixture Linkage Disequilibrium
Collins-Schramm, Heather E., Phillips, Carolyn M., Operario, Darwin J., Lee, Jane S., Weber, James L., Hanson, Robert L., ...
Mapping by admixture linkage disequilibrium (MALD) is a potentially powerful technique for the mapping of complex genetic diseases. The practical requirements of this method include (a) a set of...
Seldin, Michael F., Morii, Takanobu, Collins-Schramm, Heather E., Chima, Bill, Kittles, Rick, Criswell, Lindsey A., ...
Theoretically, markers that distinguish European from West African ancestry can be used to examine the origin of chromosomal segments in individual African Americans. In this study, putative...
AAA ATPases regulate membrane association of yeast oxysterol binding proteins and sterol metabolism
Wang, Penghua, Zhang, Yong, Li, Hongzhe, Chieu, Hai Kee, Munn, Alan L, Yang, Hongyuan
The yeast genome encodes seven oxysterol binding protein homologs, Osh1p–Osh7p, which have been implicated in regulating intracellular lipid and vesicular transport. Here, we show that both Osh6p...
Complex human diseases are often due to multiple disease genes with variable age of onset, as well as both genetic and environmental risk factors. In order to simultaneously consider two possible...