Hongyue Dai

Chromosome 20q Amplification Regulates in Vitro Response to Kinesin-5 Inhibitor (2008)

Aimee L. Jackson, Mao Mao, Sumire Kobayashi, Teresa Ward, Matthew Biery, Hongyue Dai, ...

We identified gene expression signatures predicting responsiveness to a Kinesin-5 (KIF11) inhibitor (Kinesin-5i) in cultured colon tumor cell lines. Genes predicting resistance to Kinesin-5i were...

Chromosome 20q Amplification Regulates in Vitro Response to Kinesin-5 Inhibitor (2008)

Aimee L. Jackson, Mao Mao, Sumire Kobayashi, Teresa Ward, Matthew Biery, Hongyue Dai, ...

We identified gene expression signatures predicting responsiveness to a Kinesin-5 (KIF11) inhibitor (Kinesin-5i) in cultured colon tumor cell lines. Genes predicting resistance to Kinesin-5i were...

PPARα siRNA–Treated Expression Profiles Uncover the Causal Sufficiency Network for Compound-Induced Liver Hypertrophy (2007)

Xudong Dai, Hongyue Dai, David L. Lewis, Chang-kyu Lee, Andy G. Spencer, ...

Uncovering pathways underlying drug-induced toxicity is a fundamental objective in the field of toxicogenomics. Developing mechanism-based toxicity biomarkers requires the identification of such...

PPARα siRNA-Treated Expression Profiles Uncover the Causal Sufficiency Network for Compound-Induced Liver Hypertrophy (2007)

Xudong Dai, Hongyue Dai, David L. Lewis, Chang-kyu Lee, Andy G. Spencer, ...

Uncovering pathways underlying drug-induced toxicity is a fundamental objective in the field of toxicogenomics. Developing mechanism-based toxicity biomarkers requires the identification of such...

The Extremely High Energy Cosmic Rays (1998)

Yoshida, Shigeru, Dai, Hongyue

Experimental results from Haverah Park, Yakutsk, AGASA and Fly's Eye are reviewed. All these experiments work in the energy range above 0.1 EeV. The 'dip' structure around 3 EeV in the energy...

Journal, 479 : (1997)

Shigeru Yoshida, Hongyue Dai

We discuss in some detail the production of extremely high energy (EHE) neutrinos with energies above 1018 eV. The most certain process for producing such neutrinos results from photopion production...

Extremely High Energy Neutrinos and their Detection (1996)

Yoshida, Shigeru, Dai, Hongyue, Jui, Charles C. H., Sommers, Paul

We discuss in some detail the production of extremely high energy (EHE) neutrinos with energies above 10^18 eV. The most certain process for producing such neutrinos results from photopion production...

Use of hybridization kinetics for differentiating specific from non-specific binding to oligonucleotide microarrays

Dai, Hongyue, Meyer, Michael, Stepaniants, Sergey, Ziman, Michael, Stoughton, Roland

Hybridization kinetics were found to be significantly different for specific and non-specific binding of labeled cRNA to surface-bound oligonucleotides on microarrays. We show direct evidence that in...

Gene expression changes associated with progression and response in chronic myeloid leukemia

Radich, Jerald P., Dai, Hongyue, Mao, Mao, Oehler, Vivian, Schelter, Jan, Druker, Brian, ...

Chronic myeloid leukemia (CML) is a hematopoietic stem cell disease with distinct biological and clinical features. The biologic basis of the stereotypical progression from chronic phase through...

Use of hybridization kinetics for differentiating specific from non-specific binding to oligonucleotide microarrays

Dai, Hongyue, Meyer, Michael, Stepaniants, Sergey, Ziman, Michael, Stoughton, Roland

Hybridization kinetics were found to be significantly different for specific and non-specific binding of labeled cRNA to surface-bound oligonucleotides on microarrays. We show direct evidence that in...

Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival

Chang, Howard Y., Nuyten, Dimitry S. A., Sneddon, Julie B., Hastie, Trevor, Tibshirani, Robert, Sørlie, Therese, ...

Based on the hypothesis that features of the molecular program of normal wound healing might play an important role in cancer metastasis, we previously identified consistent features in the...

Gene expression changes associated with progression and response in chronic myeloid leukemia

Radich, Jerald P., Dai, Hongyue, Mao, Mao, Oehler, Vivian, Schelter, Jan, Druker, Brian, ...

Chronic myeloid leukemia (CML) is a hematopoietic stem cell disease with distinct biological and clinical features. The biologic basis of the stereotypical progression from chronic phase through...

PPARα siRNA–Treated Expression Profiles Uncover the Causal Sufficiency Network for Compound-Induced Liver Hypertrophy

Dai, Xudong, Souza, Angus T. De, Dai, Hongyue, Lewis, David L, Lee, Chang-kyu, Spencer, Andy G, ...

Uncovering pathways underlying drug-induced toxicity is a fundamental objective in the field of toxicogenomics. Developing mechanism-based toxicity biomarkers requires the identification of such...

Transcripts Targeted by the MicroRNA-16 Family Cooperatively Regulate Cell Cycle Progression▿ †

Linsley, Peter S., Schelter, Janell, Burchard, Julja, Kibukawa, Miho, Martin, Melissa M., Bartz, Steven R., ...

microRNAs (miRNAs) are abundant, ∼21-nucleotide, noncoding regulatory RNAs. Each miRNA may regulate hundreds of mRNA targets, but the identities of these targets and the processes they regulate are...