Fuqu Yu, Josephine N. Harada, Helen J. Brown, Hongyu Deng, Moon Jung Song, Ting-Ting Wu, ...
The herpesvirus life cycle has two distinct phases: latency and lytic replication. The balance between these two phases is critical for viral pathogenesis. It is believed that cellular signals...
Thesis (Ph. D.)--University of Rochester, 1998.
Deng, Hongyu, Dewhurst, Stephen
Sequences present at the genomic termini of herpesviruses become linked during lytic-phase replication and provide the substrate for cleavage and packaging of unit length viral genomes. We have...
NF-κB Inhibits Gammaherpesvirus Lytic Replication
Brown, Helen J., Song, Moon Jung, Deng, Hongyu, Wu, Ting-Ting, Cheng, Genhong, Sun, Ren
Nasopharyngeal carcinoma, Kaposi's sarcoma, and B-cell lymphomas are human malignancies associated with gammaherpesvirus infections. Members of this virus family are characterized by their ability to...
Song, Moon Jung, Deng, Hongyu, Sun, Ren
Replication and transcription activator (RTA) (also referred to as ORF50), an immediate-early gene product of Kaposi's sarcoma-associated herpesvirus (KSHV)/(human herpesvirus 8), plays a critical...
Zhu, Jiaming, Trang, Phong, Kim, Kihoon, Zhou, Tianhong, Deng, Hongyu, Liu, Fenyong
Ribonuclease P (RNase P) complexed with external guide sequence (EGS) represents a nucleic acid-based gene interference approach to knock-down gene expression. Unlike other strategies, such as...
Deng, Hongyu, Chu, Julia T., Park, No-Hee, Sun, Ren
Human gammaherpesviruses are associated with lymphomas and other malignancies. Murine gammaherpesvirus 68 (MHV-68) infection of mice has emerged as a model for understanding gammaherpesvirus...
Rickabaugh, Tammy M., Brown, Helen J., Wu, Ting-Ting, Song, Moon Jung, Hwang, Seungmin, Deng, Hongyu, ...
Murine gammaherpesvirus 68 (MHV-68), Kaposi's sarcoma-associated herpesvirus (HHV-8), and Epstein-Barr virus (EBV) are all members of the gammaherpesvirus family, characterized by their ability to...
Chang, Margaret, Brown, Helen J., Collado-Hidalgo, Alicia, Arevalo, Jesusa M., Galic, Zoran, Symensma, Tonia L., ...
Reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV) lytic replication is mediated by the viral RTA transcription factor, but little is known about the physiological processes controlling...
Deng, Hongyu, Song, Moon Jung, Chu, Julia T., Sun, Ren
Human herpesvirus 8 (HHV-8; Kaposi's sarcoma-associated herpesvirus is linked to Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's disease (MCD), all of which are...
Deng, Hongyu, Dewhurst, Stephen
Sequences present at the genomic termini of herpesviruses become linked during lytic-phase replication and provide the substrate for cleavage and packaging of unit length viral genomes. We have...
Deng, Hongyu, Song, Moon Jung, Chu, Julia T., Sun, Ren
Human herpesvirus 8 (HHV-8; Kaposi's sarcoma-associated herpesvirus is linked to Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's disease (MCD), all of which are...
NF-κB Inhibits Gammaherpesvirus Lytic Replication
Brown, Helen J., Song, Moon Jung, Deng, Hongyu, Wu, Ting-Ting, Cheng, Genhong, Sun, Ren
Nasopharyngeal carcinoma, Kaposi's sarcoma, and B-cell lymphomas are human malignancies associated with gammaherpesvirus infections. Members of this virus family are characterized by their ability to...
Song, Moon Jung, Deng, Hongyu, Sun, Ren
Replication and transcription activator (RTA) (also referred to as ORF50), an immediate-early gene product of Kaposi's sarcoma-associated herpesvirus (KSHV)/(human herpesvirus 8), plays a critical...
Zhu, Jiaming, Trang, Phong, Kim, Kihoon, Zhou, Tianhong, Deng, Hongyu, Liu, Fenyong
Ribonuclease P (RNase P) complexed with external guide sequence (EGS) represents a nucleic acid-based gene interference approach to knock-down gene expression. Unlike other strategies, such as...
Deng, Hongyu, Chu, Julia T., Park, No-Hee, Sun, Ren
Human gammaherpesviruses are associated with lymphomas and other malignancies. Murine gammaherpesvirus 68 (MHV-68) infection of mice has emerged as a model for understanding gammaherpesvirus...
Rickabaugh, Tammy M., Brown, Helen J., Wu, Ting-Ting, Song, Moon Jung, Hwang, Seungmin, Deng, Hongyu, ...
Murine gammaherpesvirus 68 (MHV-68), Kaposi's sarcoma-associated herpesvirus (HHV-8), and Epstein-Barr virus (EBV) are all members of the gammaherpesvirus family, characterized by their ability to...
Chang, Margaret, Brown, Helen J., Collado-Hidalgo, Alicia, Arevalo, Jesusa M., Galic, Zoran, Symensma, Tonia L., ...
Reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV) lytic replication is mediated by the viral RTA transcription factor, but little is known about the physiological processes controlling...
ORF18 Is a Transfactor That Is Essential for Late Gene Transcription of a Gammaherpesvirus
Arumugaswami, Vaithilingaraja, Wu, Ting-Ting, Martinez-Guzman, DeeAnn, Jia, Qingmei, Deng, Hongyu, Reyes, Nichole, ...
Lytic replication of the tumor-associated human gammaherpesviruses Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus has important implications in pathogenesis and tumorigenesis....
Systematic Identification of Cellular Signals Reactivating Kaposi Sarcoma–Associated Herpesvirus
Yu, Fuqu, Harada, Josephine N, Brown, Helen J, Deng, Hongyu, Song, Moon Jung, Wu, Ting-Ting, ...
The herpesvirus life cycle has two distinct phases: latency and lytic replication. The balance between these two phases is critical for viral pathogenesis. It is believed that cellular signals...
Wong, Elaine, Wu, Ting-Ting, Reyes, Nichole, Deng, Hongyu, Sun, Ren
Open reading frame 24 (ORF24) of murine gammaherpesvirus 68 (MHV-68) is conserved among beta- and gammaherpesviruses; however, its function in viral replication has not been defined. Using MHV-68 as...
Bortz, Eric, Wang, Lili, Jia, Qingmei, Wu, Ting-Ting, Whitelegge, Julian P., Deng, Hongyu, ...
The tegument, a semiordered matrix of proteins overlying the nucleocapsid and underlying the virion envelope, in viruses in the gamma subfamily of Herpesviridae is poorly understood. Murine...