Hiroyuki Mutoh

The basic helix–loop–helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression

Mutoh, Hiroyuki, Fung, Brenda P., Naya, Francisco J., Tsai, Ming-Jer, Nishitani, Junko, Leiter, Andrew B.

The gene encoding the hormone secretin is expressed only in enteroendocrine S cells and insulin-producing pancreatic β cells during development. A 120-bp enhancer directs cell-specific expression of...

Conversion of Lactobacillus pentosus d-Lactate Dehydrogenase to a d-Hydroxyisocaproate Dehydrogenase through a Single Amino Acid Replacement

Tokuda, Chizuka, Ishikura, Yoshiro, Shigematsu, Mayu, Mutoh, Hiroyuki, Tsuzuki, Shino, Nakahira, Yusaku, ...

The single amino acid replacement of Tyr52 with Leu drastically increased the activity of Lactobacillus pentosus NAD-dependent d-lactate dehydrogenase toward larger aliphatic or aromatic 2-ketoacid...

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice

Naya, Francisco J., Huang, Hsiang-Po, Qiu, Yuhong, Mutoh, Hiroyuki, DeMayo, Francesco J., Leiter, Andrew B., ...

Candidate transcription factors involved in pancreatic endocrine development have been isolated using insulin gene regulation as a paradigm. The cell-type restricted basic helix–loop–helix (bHLH)...

The basic helix–loop–helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells

Mutoh, Hiroyuki, Naya, Francisco J., Tsai, Ming-Jer, Leiter, Andrew B.

The major epithelial cell types lining the intestine comprise a perpetually self-renewing population of cells that differentiate continuously from a stem cell in the intestinal crypts....

The basic helix–loop–helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression

Mutoh, Hiroyuki, Fung, Brenda P., Naya, Francisco J., Tsai, Ming-Jer, Nishitani, Junko, Leiter, Andrew B.

The gene encoding the hormone secretin is expressed only in enteroendocrine S cells and insulin-producing pancreatic β cells during development. A 120-bp enhancer directs cell-specific expression of...

Conversion of Lactobacillus pentosus d-Lactate Dehydrogenase to a d-Hydroxyisocaproate Dehydrogenase through a Single Amino Acid Replacement

Tokuda, Chizuka, Ishikura, Yoshiro, Shigematsu, Mayu, Mutoh, Hiroyuki, Tsuzuki, Shino, Nakahira, Yusaku, ...

The single amino acid replacement of Tyr52 with Leu drastically increased the activity of Lactobacillus pentosus NAD-dependent d-lactate dehydrogenase toward larger aliphatic or aromatic 2-ketoacid...

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice

Naya, Francisco J., Huang, Hsiang-Po, Qiu, Yuhong, Mutoh, Hiroyuki, DeMayo, Francesco J., Leiter, Andrew B., ...

Candidate transcription factors involved in pancreatic endocrine development have been isolated using insulin gene regulation as a paradigm. The cell-type restricted basic helix–loop–helix (bHLH)...

The basic helix–loop–helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells

Mutoh, Hiroyuki, Naya, Francisco J., Tsai, Ming-Jer, Leiter, Andrew B.

The major epithelial cell types lining the intestine comprise a perpetually self-renewing population of cells that differentiate continuously from a stem cell in the intestinal crypts....