Scientific Commons: Hildburg Beier

Vergleichende Untersuchungen zur Genetik und Physiologie der Infektion der verwandten Phagen T3 und T7. (1973)

Freiburg (Breisgau), Univ., Fak. f. Biologie, Diss. 1973. (Nicht f. d. Austausch.).

Misreading of termination codons in eukaryotes by natural nonsense suppressor tRNAs

Translational stop codon readthrough provides a regulatory mechanism of gene expression that is extensively utilised by positive-sense ssRNA viruses. The misreading of termination codons is achieved...

Translational nonsense codon suppression as indicator for functional pre-tRNA splicing in transformed Arabidopsis hypocotyl-derived calli

Akama, Kazuhito, Beier, Hildburg

The transient expression of three novel plant amber suppressors derived from a cloned Nicotiana tRNASer(CGA), an Arabidopsis intron-containing tRNATyr(GTA) and an Arabidopsis intron-containing...

Genetic Map of Bacteriophage T3

Beier, Hildburg, Hausmann, Rudolf

About 200 amber mutants of phage T3 were found to lie in 14 different genes. These genes are homologous to known T7 genes. The genetic map of T3 is very similar to that of T7.

Plant tRNA ligases are multifunctional enzymes that have diverged in sequence and substrate specificity from RNA ligases of other phylogenetic origins

Englert, Markus, Beier, Hildburg

Pre-tRNA splicing is an essential process in all eukaryotes. It requires the concerted action of an endonuclease to remove the intron and a ligase for joining the resulting tRNA halves as studied...

UAG readthrough during TMV RNA translation: isolation and sequence of two tRNAsTyr with suppressor activity from tobacco plants

Beier, Hildburg, Barciszewska, Miroslawa, Krupp, Guido, Mitnacht, Rita, Gross, Hans J.

The hypothetical replicase or replicase subunit cistron in the 5'-proximal part of tobacco mosaic virus (TMV) RNA yields a major 126-K protein and a minor 183-K `readthrough' protein in vivo and in...

The molecular basis for the differential translation of TMV RNA in tobacco protoplasts and wheat germ extracts

Beier, Hildburg, Barciszewska, Miroslawa, Sickinger, Hans-Dieter

Translation of tobacco mosaic virus (TMV) RNA in tobacco protoplasts yields the 17.5-K coat protein, a 126-K protein and a 183-K protein which is generated by an efficient readthrough over the UAG...

Dramatic events in ciliate evolution: alteration of UAA and UAG termination codons to glutamine codons due to anticodon mutations in two Tetrahymena tRNAsGln

Hanyu, Naohiro, Kuchino, Yoshiyuki, Nishimura, Susumu, Beier, Hildburg

The three major glutamine tRNAs of Tetrahymena thermophila were isolated and their nucleotide sequences determined by post-labeling techniques. Two of these tRNAsGln show unusual codon recognition: a...

Structure–function analysis of the kinase-CPD domain of yeast tRNA ligase (Trl1) and requirements for complementation of tRNA splicing by a plant Trl1 homolog

Wang, Li Kai, Schwer, Beate, Englert, Markus, Beier, Hildburg, Shuman, Stewart

Trl1 is an essential 827 amino acid enzyme that executes the end-healing and end-sealing steps of tRNA splicing in Saccharomyces cerevisiae. Trl1 consists of two domains—an N-terminal ligase...