Henner Brinkmann

Phylogenomics: the beginning of incongruence? (2008)

Jeffroy, Olivier, Brinkmann, Henner, Delsuc, Frédéric, Philippe, Hervé

Until recently, molecular phylogenies based on a single or few orthologous genes often yielded contradictory results. Using multiple genes in a large concatenation was proposed to end these...

Tunicates and not cephalochordates are the closest living relatives of vertebrates. (2008)

Delsuc, Frédéric, Brinkmann, Henner, Chourrout, Daniel, Philippe, Hervé

Tunicates or urochordates (appendicularians, salps and sea squirts), cephalochordates (lancelets) and vertebrates (including lamprey and hagfish) constitute the three extant groups of chordate...

Phylogenomics: the beginning of incongruence? (2008)

Jeffroy, Olivier, Brinkmann, Henner, Delsuc, Frédéric, Philippe, Hervé

Until recently, molecular phylogenies based on a single or few orthologous genes often yielded contradictory results. Using multiple genes in a large concatenation was proposed to end these...

Tunicates and not cephalochordates are the closest living relatives of vertebrates. (2008)

Delsuc, Frédéric, Brinkmann, Henner, Chourrout, Daniel, Philippe, Hervé

Tunicates or urochordates (appendicularians, salps and sea squirts), cephalochordates (lancelets) and vertebrates (including lamprey and hagfish) constitute the three extant groups of chordate...

Phylogenomics and the reconstruction of the tree of life. (2007)

Delsuc, Frédéric, Brinkmann, Henner, Philippe, Hervé

As more complete genomes are sequenced, phylogenetic analysis is entering a new era - that of phylogenomics. One branch of this expanding field aims to reconstruct the evolutionary history of...

Phylogenomics and the reconstruction of the tree of life. (2007)

Delsuc, Frédéric, Brinkmann, Henner, Philippe, Hervé

As more complete genomes are sequenced, phylogenetic analysis is entering a new era - that of phylogenomics. One branch of this expanding field aims to reconstruct the evolutionary history of...

Phylogenomics (2007)

Philippe, Hervé, Delsuc, Frédéric, Brinkmann, Henner, Lartillot, Nicolas

The continuous flow of genomic data is creating unprecedented opportunities for the reconstruction of molecular phylogenies. Access to wholegenome data means that phylogenetic analysis can now be...

Heterotachy and long-branch attraction in phylogenetics. (2007)

Philippe, Hervé, Zhou, Yan, Brinkmann, Henner, Rodrigue, Nicolas, Delsuc, Frédéric

BACKGROUND: Probabilistic methods have progressively supplanted the Maximum Parsimony (MP) method for inferring phylogenetic trees. One of the major reasons for this shift was that MP is much more...

Phylogenomics (2007)

Philippe, Hervé, Delsuc, Frédéric, Brinkmann, Henner, Lartillot, Nicolas

The continuous flow of genomic data is creating unprecedented opportunities for the reconstruction of molecular phylogenies. Access to wholegenome data means that phylogenetic analysis can now be...

Heterotachy and long-branch attraction in phylogenetics. (2007)

Philippe, Hervé, Zhou, Yan, Brinkmann, Henner, Rodrigue, Nicolas, Delsuc, Frédéric

BACKGROUND: Probabilistic methods have progressively supplanted the Maximum Parsimony (MP) method for inferring phylogenetic trees. One of the major reasons for this shift was that MP is much more...

Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer (2007)

Villiard, Éric, Brinkmann, Henner, Moiseeva, Olga, Mallette, Frédérick A, Ferbeyre, Gerardo, Roy, Stéphane

Abstract Background Urodele amphibians like the axolotl are unique among vertebrates in their ability to regenerate and their resistance to develop cancers. It is unknown whether these traits are...

Glycerate kinase of the hyperthermophilic archaeon Thermoproteus tenax: new insights into the phylogenetic distribution and physiological role of members of the three different glycerate kinase classes (2007)

Kehrer, Daniel, Ahmed, Hatim, Brinkmann, Henner, Siebers, Bettina

Abstract Background The presence of the branched Entner-Doudoroff (ED) pathway in two hyperthermophilic Crenarchaea, the anaerobe Thermoproteus tenax and the aerobe Sulfolobus solfataricus , was...

Suppression of long-branch attraction artefacts in the animal phylogeny using a site-heterogeneous model (2007)

Lartillot, Nicolas, Brinkmann, Henner, Philippe, Hervé

Abstract Background Thanks to the large amount of signal contained in genome-wide sequence alignments, phylogenomic analyses are converging towards highly supported trees. However, high statistical...

Three rounds (1R/2R/3R) of genome duplications and the evolution of the glycolytic pathway in vertebrates (2006)

Steinke, Dirk, Hoegg, Simone, Brinkmann, Henner, Meyer, Axel

Abstract Background Evolution of the deuterostome lineage was accompanied by an increase in systematic complexity especially with regard to highly specialized tissues and organs. Based on the...

Three rounds (1R/2R/3R) of genome duplications and the evolution of the glycolytic pathway in vertebrates (2006)

Steinke, Dirk, Hoegg, Simone, Brinkmann, Henner, Meyer, Axel

Affiliation: Henner Brinkmann : Département de biochimie, Faculté de médecine, Université de Montreal

Heterotachy and long-branch attraction in phylogenetics (2005)

Philippe, Hervé, Zhou, Yan, Brinkmann, Henner, Rodrigue, Nicolas, Delsuc, Frédéric

Abstract Background Probabilistic methods have progressively supplanted the Maximum Parsimony (MP) method for inferring phylogenetic trees. One of the major reasons for this shift was that MP is much...

Heterotachy and long-branch attraction in phylogenetics (2005)

Philippe, Hervé, Zhou, Yan, Brinkmann, Henner, Rodrigue, Nicolas, Delsuc, Frédéric

Affiliation: Département de Biochimie, Faculté de médecine, Université de Montréal

Cloning and sequence analysis of cDNAs encoding the cytosolic precursors of subunits GapA and GapB of chloroplast glyceraldehyde-3-phosphate dehydrogenase from pea and spinach (1989)

Brinkmann, Henner, Cerff, Rüdiger, Salomon, Michael, Soll, Jürgen

Chloroplast glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is composed of two different subunits, GapA and GapB. cDNA clones containing the entire coding sequences of the cytosolic precursors for...

Pyruvate Kinase of the Hyperthermophilic Crenarchaeote Thermoproteus tenax: Physiological Role and Phylogenetic Aspects

Schramm, Alexander, Siebers, Bettina, Tjaden, Britta, Brinkmann, Henner, Hensel, Reinhard

Pyruvate kinase (PK; EC 2.7.1.40) of Thermoproteus tenax was purified to homogeneity, and its coding gene was cloned and expressed in Escherichia coli. It represents a homomeric tetramer with a...

The Molybdenum Cofactor Biosynthetic Protein Cnx1 Complements Molybdate-Repairable Mutants, Transfers Molybdenum to the Metal Binding Pterin, and Is Associated with the Cytoskeleton

Schwarz, Günter, Schulze, Jutta, Bittner, Florian, Eilers, Thomas, Kuper, Jochen, Bollmann, Gabriele, ...

Molybdenum (Mo) plays an essential role in the active site of all eukaryotic Mo-containing enzymes. In plants, Mo enzymes are important for nitrate assimilation, phytohormone synthesis, and purine...

The analysis of 100 genes supports the grouping of three highly divergent amoebae: Dictyostelium, Entamoeba, and Mastigamoeba

Bapteste, Eric, Brinkmann, Henner, Lee, Jennifer A., Moore, Dorothy V., Sensen, Christoph W., Gordon, Paul, ...

The phylogenetic relationships of amoebae are poorly resolved. To address this difficult question, we have sequenced 1,280 expressed sequence tags from Mastigamoeba balamuthi and assembled a large...

Nuclear protein-coding genes support lungfish and not the coelacanth as the closest living relatives of land vertebrates

Brinkmann, Henner, Venkatesh, Byrappa, Brenner, Sydney, Meyer, Axel

The colonization of land by tetrapod ancestors is one of the major questions in the evolution of vertebrates. Despite intense molecular phylogenetic research on this problem during the last 15 years,...

Only a Few Fungal Species Dominate Highly Diverse Mycofloras Associated with the Common Reed

Neubert, Karin, Mendgen, Kurt, Brinkmann, Henner, Wirsel, Stefan G. R.

Plants are naturally colonized by many fungal species that produce effects ranging from beneficial to pathogenic. However, how many of these fungi are linked with a single host plant has not been...

Pyruvate Kinase of the Hyperthermophilic Crenarchaeote Thermoproteus tenax: Physiological Role and Phylogenetic Aspects

Schramm, Alexander, Siebers, Bettina, Tjaden, Britta, Brinkmann, Henner, Hensel, Reinhard

Pyruvate kinase (PK; EC 2.7.1.40) of Thermoproteus tenax was purified to homogeneity, and its coding gene was cloned and expressed in Escherichia coli. It represents a homomeric tetramer with a...

The Molybdenum Cofactor Biosynthetic Protein Cnx1 Complements Molybdate-Repairable Mutants, Transfers Molybdenum to the Metal Binding Pterin, and Is Associated with the Cytoskeleton

Schwarz, Günter, Schulze, Jutta, Bittner, Florian, Eilers, Thomas, Kuper, Jochen, Bollmann, Gabriele, ...

Molybdenum (Mo) plays an essential role in the active site of all eukaryotic Mo-containing enzymes. In plants, Mo enzymes are important for nitrate assimilation, phytohormone synthesis, and purine...

The analysis of 100 genes supports the grouping of three highly divergent amoebae: Dictyostelium, Entamoeba, and Mastigamoeba

Bapteste, Eric, Brinkmann, Henner, Lee, Jennifer A., Moore, Dorothy V., Sensen, Christoph W., Gordon, Paul, ...

The phylogenetic relationships of amoebae are poorly resolved. To address this difficult question, we have sequenced 1,280 expressed sequence tags from Mastigamoeba balamuthi and assembled a large...

Nuclear protein-coding genes support lungfish and not the coelacanth as the closest living relatives of land vertebrates

Brinkmann, Henner, Venkatesh, Byrappa, Brenner, Sydney, Meyer, Axel

The colonization of land by tetrapod ancestors is one of the major questions in the evolution of vertebrates. Despite intense molecular phylogenetic research on this problem during the last 15 years,...

Only a Few Fungal Species Dominate Highly Diverse Mycofloras Associated with the Common Reed

Neubert, Karin, Mendgen, Kurt, Brinkmann, Henner, Wirsel, Stefan G. R.

Plants are naturally colonized by many fungal species that produce effects ranging from beneficial to pathogenic. However, how many of these fungi are linked with a single host plant has not been...

Multiple overseas dispersal in amphibians.

Vences, Miguel, Vieites, David R, Glaw, Frank, Brinkmann, Henner, Kosuch, Joachim, Veith, Michael, ...

Amphibians are thought to be unable to disperse over ocean barriers because they do not tolerate the osmotic stress of salt water. Their distribution patterns have therefore generally been explained...

Acoel Flatworms Are Not Platyhelminthes: Evidence from Phylogenomics

Philippe, Hervé, Brinkmann, Henner, Martinez, Pedro, Riutort, Marta, Baguñà, Jaume

Acoel flatworms are small marine worms traditionally considered to belong to the phylum Platyhelminthes. However, molecular phylogenetic analyses suggest that acoels are not members of...