Heike Beck

Essential Role for Mitochondrial Thioredoxin Reductase in Hematopoiesis, Heart Development, and Heart Function

Conrad, Marcus, Jakupoglu, Cemile, Moreno, Stéphanie G., Lippl, Stefanie, Banjac, Ana, Schneider, Manuela, ...

Oxygen radicals regulate many physiological processes, such as signaling, proliferation, and apoptosis, and thus play a pivotal role in pathophysiology and disease development. There are at least two...

Essential Role for Mitochondrial Thioredoxin Reductase in Hematopoiesis, Heart Development, and Heart Function

Conrad, Marcus, Jakupoglu, Cemile, Moreno, Stéphanie G., Lippl, Stefanie, Banjac, Ana, Schneider, Manuela, ...

Oxygen radicals regulate many physiological processes, such as signaling, proliferation, and apoptosis, and thus play a pivotal role in pathophysiology and disease development. There are at least two...

Expression of Angiopoietin-1, Angiopoietin-2, and Tie Receptors after Middle Cerebral Artery Occlusion in the Rat

Beck, Heike, Acker, Till, Wiessner, Christoph, Allegrini, Peter R., Plate, Karl H.

Vascular endothelial growth factor (VEGF), a key regulator of vasculogenesis and embryonic angiogenesis, was recently found to be up-regulated in an animal model of stroke. Unlike VEGF, angiopoietin...

The Role of Thioredoxin Reductases in Brain Development

Soerensen, Jonna, Jakupoglu, Cemile, Beck, Heike, Förster, Heidi, Schmidt, Jörg, Schmahl, Wolfgang, ...

The thioredoxin-dependent system is an essential regulator of cellular redox balance. Since oxidative stress has been linked with neurodegenerative disease, we studied the roles of thioredoxin...