Haruo Ikeda

Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis

Ikeda, Haruo, Nonomiya, Tomoko, Usami, Masayo, Ohta, Toshio, Ōmura, Satoshi

Analysis of the gene cluster from Streptomyces avermitilis that governs the biosynthesis of the polyketide anthelmintic avermectin revealed that it contains four large ORFs encoding giant...

Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites

Ōmura, Satoshi, Ikeda, Haruo, Ishikawa, Jun, Hanamoto, Akiharu, Takahashi, Chigusa, Shinose, Mayumi, ...

Streptomyces avermitilis is a soil bacterium that carries out not only a complex morphological differentiation but also the production of secondary metabolites, one of which, avermectin, is...

Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism

Ueda, Kenji, Yamashita, Atsushi, Ishikawa, Jun, Shimada, Masafumi, Watsuji, Tomo-o, Morimura, Kohji, ...

Symbiobacterium thermophilum is an uncultivable bacterium isolated from compost that depends on microbial commensalism. The 16S ribosomal DNA-based phylogeny suggests that this bacterium belongs to...

Hyper-inducible expression system for streptomycetes

Herai, Sachio, Hashimoto, Yoshiteru, Higashibata, Hiroki, Maseda, Hideaki, Ikeda, Haruo, Ōmura, Satoshi, ...

Streptomycetes produce useful enzymes and a wide variety of secondary metabolites with potent biological activities (e.g., antibiotics, immunosuppressors, pesticides, etc.). Despite their importance...

Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis

Ikeda, Haruo, Nonomiya, Tomoko, Usami, Masayo, Ohta, Toshio, Ōmura, Satoshi

Analysis of the gene cluster from Streptomyces avermitilis that governs the biosynthesis of the polyketide anthelmintic avermectin revealed that it contains four large ORFs encoding giant...

Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites

Ōmura, Satoshi, Ikeda, Haruo, Ishikawa, Jun, Hanamoto, Akiharu, Takahashi, Chigusa, Shinose, Mayumi, ...

Streptomyces avermitilis is a soil bacterium that carries out not only a complex morphological differentiation but also the production of secondary metabolites, one of which, avermectin, is...

Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism

Ueda, Kenji, Yamashita, Atsushi, Ishikawa, Jun, Shimada, Masafumi, Watsuji, Tomo-o, Morimura, Kohji, ...

Symbiobacterium thermophilum is an uncultivable bacterium isolated from compost that depends on microbial commensalism. The 16S ribosomal DNA-based phylogeny suggests that this bacterium belongs to...

Hyper-inducible expression system for streptomycetes

Herai, Sachio, Hashimoto, Yoshiteru, Higashibata, Hiroki, Maseda, Hideaki, Ikeda, Haruo, Ōmura, Satoshi, ...

Streptomycetes produce useful enzymes and a wide variety of secondary metabolites with potent biological activities (e.g., antibiotics, immunosuppressors, pesticides, etc.). Despite their importance...

Genome Sequence of the Streptomycin-Producing Microorganism Streptomyces griseus IFO 13350▿ †

Ohnishi, Yasuo, Ishikawa, Jun, Hara, Hirofumi, Suzuki, Hirokazu, Ikenoya, Miwa, Ikeda, Haruo, ...

We determined the complete genome sequence of Streptomyces griseus IFO 13350, a soil bacterium producing an antituberculosis agent, streptomycin, which is the first aminoglycoside antibiotic,...