Klockow,Boris, Tichelaar,Willem, Madden,Dean R., Niemann,Hartmut H., Akiba,Toshihiko, Hirose,Keiko, ...
Here we show that Dictyostelium discoideum dynamin A is a fast GTPase, binds to negatively charged lipids, and self-assembles into rings and helices in a nucleotide-dependent manner, similar to human...
Klockow, Boris, Tichelaar, Willem, Madden, Dean R., Niemann, Hartmut H., Akiba, Toshihiko, Hirose, Keiko, ...
Here we show that Dictyostelium discoideum dynamin A is a fast GTPase, binds to negatively charged lipids, and self-assembles into rings and helices in a nucleotide-dependent manner, similar to human...
Crystal structure of a dynamin GTPase domain (2001)
Niemann,Hartmut H., Knetsch,Menno L. W., Scherer,Anna, Manstein,Dietmar J., Kull,F. Jon
Dynamins form a family of multidomain GTPases involved in endocytosis, vesicle trafficking and maintenance of mitochondrial morphology. In contrast to the classical switch GTPases, a force-generating...
Crystal structure of a dynamin GTPase domain (2001)
Niemann,Hartmut H., Knetsch,Menno L. W., Scherer,Anna, Manstein,Dietmar J., Kull,F. Jon
Dynamins form a family of multidomain GTPases involved in endocytosis, vesicle trafficking and maintenance of mitochondrial morphology. In contrast to the classical switch GTPases, a force-generating...
Crystal structure of a dynamin GTPase domain (2001)
Niemann, Hartmut H., Knetsch, Menno L. W., Scherer, Anna, Manstein, Dietmar J., Kull, F. Jon
Dynamins form a family of multidomain GTPases involved in endocytosis, vesicle trafficking and maintenance of mitochondrial morphology. In contrast to the classical switch GTPases, a force-generating...
Crystal structure of a dynamin GTPase domain (2001)
Niemann, Hartmut H., Knetsch, Menno L. W., Scherer, Anna, Manstein, Dietmar J., Kull, F. Jon
Dynamins form a family of multidomain GTPases involved in endocytosis, vesicle trafficking and maintenance of mitochondrial morphology. In contrast to the classical switch GTPases, a force-generating...
Crystal structure of a dynamin GTPase domain in both nucleotide-free and GDP-bound forms
Niemann, Hartmut H., Knetsch, Menno L.W., Scherer, Anna, Manstein, Dietmar J., Kull, F.Jon
Dynamins form a family of multidomain GTPases involved in endocytosis, vesicle trafficking and maintenance of mitochondrial morphology. In contrast to the classical switch GTPases, a force-generating...
The dynamin A ring complex: molecular organization and nucleotide-dependent conformational changes
Klockow, Boris, Tichelaar, Willem, Madden, Dean R., Niemann, Hartmut H., Akiba, Toshihiko, Hirose, Keiko, ...
Here we show that Dictyostelium discoideum dynamin A is a fast GTPase, binds to negatively charged lipids, and self-assembles into rings and helices in a nucleotide-dependent manner, similar to human...
Crystal structure of a dynamin GTPase domain in both nucleotide-free and GDP-bound forms
Niemann, Hartmut H., Knetsch, Menno L.W., Scherer, Anna, Manstein, Dietmar J., Kull, F.Jon
Dynamins form a family of multidomain GTPases involved in endocytosis, vesicle trafficking and maintenance of mitochondrial morphology. In contrast to the classical switch GTPases, a force-generating...
The dynamin A ring complex: molecular organization and nucleotide-dependent conformational changes
Klockow, Boris, Tichelaar, Willem, Madden, Dean R., Niemann, Hartmut H., Akiba, Toshihiko, Hirose, Keiko, ...
Here we show that Dictyostelium discoideum dynamin A is a fast GTPase, binds to negatively charged lipids, and self-assembles into rings and helices in a nucleotide-dependent manner, similar to human...
Lethal recessive myelin toxicity of prion protein lacking its central domain
Baumann, Frank, Tolnay, Markus, Brabeck, Christine, Pahnke, Jens, Kloz, Ulrich, Niemann, Hartmut H, ...
PrPC-deficient mice expressing prion protein variants with large amino-proximal deletions (termed PrPΔF) suffer from neurodegeneration, which is rescued by full-length PrPC. We now report that...
Bosse, Tanja, Ehinger, Julia, Czuchra, Aleksandra, Benesch, Stefanie, Steffen, Anika, Wu, Xunwei, ...
Activation of c-Met, the hepatocyte growth factor (HGF)/scatter factor receptor induces reorganization of the actin cytoskeleton, which drives epithelial cell scattering and motility and is exploited...
Crystal structure of Yersinia enterocolitica type III secretion chaperone SycT
Büttner, Carina R., Cornelis, Guy R., Heinz, Dirk W., Niemann, Hartmut H.
Pathogenic Yersinia species use a type III secretion (TTS) system to deliver a number of cytotoxic effector proteins directly into the mammalian host cell. To ensure effective translocation, several...