Hans-werner Mewes

Spatiotemporal Expression Control Correlates with Intragenic Scaffold Matrix Attachment Regions (S/MARs) in Arabidopsis thaliana (2006)

Igor V. Tetko, Georg Haberer, Stephen Rudd, Blake Meyers, Hans-Werner Mewes

Scaffold/matrix attachment regions (S/MARs) are essential for structural organization of the chromatin within the nucleus and serve as anchors of chromatin loop domains. A significant fraction of...

Super paramagnetic clustering of protein sequences (2005)

Tetko, Igor V, Facius, Axel, Ruepp, Andreas, Mewes, Hans-Werner

Abstract Background Detection of sequence homologues represents a challenging task that is important for the discovery of protein families and the reliable application of automatic annotation...

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004)

Tadashi Imanishi, Takeshi Itoh, Yutaka Suzuki, Claire O'Donovan, Satoshi Fukuchi, Kanako O. Koyanagi, ...

An international team has systematically validated and annotated just over 21,000 human genes using full-length cDNA, thereby providing a valuable new resource for the human genetics community.

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004)

Tadashi Imanishi, Takeshi Itoh, Yutaka Suzuki, Claire O'Donovan, Satoshi Fukuchi, Kanako O. Koyanagi, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

The Protein Information Resource: an integrated public resource of functional annotation of proteins (2002)

Cathy H. Wu, Hongzhan Huang, Leslie Arminski, Jorge Castro-alvear, Yongxing Chen, Zhang-zhi Hu, ...

The Protein Information Resource (PIR) serves as an integrated public resource of functional annotation of protein data to support genomic/proteomic research and scientific discovery. The PIR, in...

Functional and structural genomics using PEDANT (2001)

Dmitrij Frishman, Kaj Albermann, Jean Hani, Agnes Metanomski, Alfred Zollner, Hans-werner Mewes

Motivation: Enormous demand for fast and accurate analysis of biological sequences is fuelled by the pace of genome analysis efforts. There is also an acute need in reliable up-to-date genomic...

The Protein Information Resource (PIR) (2001)

Winona C. Barker, John S. Garavelli, Hongzhan Huang, Peter B. Mcgarvey, Bruce C. Orcutt, Geetha Y. Srinivasarao, ...

The Protein Information Resource (PIR) produces the largest, most comprehensive, annotated protein sequence database in the public domain, the PIRInternational Protein Sequence Database, in...

Protein Information Resource: a community resource for expert annotation of protein data (2001)

Winona C. Barker, John S. Garavelli, Zhenglin Hou, Hongzhan Huang, Robert S. Ledley, Peter B. Mcgarvey, ...

The Protein Information Resource, in collaboration with the Munich Information Center for Protein Sequences (MIPS) and the Japan International Protein Information Database (JIPID), produces the most...

The PIR-International Protein Sequence Database (1999)

Winona C. Barker, John S. Garavelli, Daniel H. Haft, Lois T. Hunt, Christopher R. Marzec, Bruce C. Orcutt, ...

From its origin the Protein Information Resource (http://www-nbrf.georgetown.edu/pir/ ) has supported research on evolution and computational biology by designing and compiling a comprehensive,...

The PIR-International Protein Sequence Database (1999)

Winona C. Barker, John S. Garavelli, Peter B. Mcgarvey, Christopher R. Marzec, Bruce C. Orcutt, Geetha Y. Srinivasarao, ...

The Protein Information Resource (PIR; http://wwwnbrf. georgetown.edu/pir/ ) supports research on molecular evolution, functional genomics, and computational biology by maintaining a comprehensive,...

Combining Diverse Evidence for Gene Recognition in Completely Sequenced Bacterial Genomes (1998)

Dmitrij Frishman, Andrey Mironov, Hans-werner Mewes, Mikhail Gelf

Analysis of anewlysequencedbacterialgenomestarts with identification of protein-coding genes. Functional assignment of proteins requires the exact knowledge of protein N-termini. We present a new...

The PIR-International Protein Sequence Database (1997)

Winona C. Barker, John S. Garavelli, Daniel H. Haft, Lois T. Hunt, Christopher R. Marzec, Bruce C. Orcutt, ...

From its origin the Protein Information Resource (http://www-nbrf.georgetown.edu/pir/ ) has supported research on evolution and computational biology by designing and compiling a comprehensive,...

Protein Information Resource: a community resource for expert annotation of protein data

Barker, Winona C., Garavelli, John S., Hou, Zhenglin, Huang, Hongzhan, Ledley, Robert S., McGarvey, Peter B., ...

The Protein Information Resource, in collaboration with the Munich Information Center for Protein Sequences (MIPS) and the Japan International Protein Information Database (JIPID), produces the most...

The Protein Information Resource: an integrated public resource of functional annotation of proteins

Wu, Cathy H., Huang, Hongzhan, Arminski, Leslie, Castro-Alvear, Jorge, Chen, Yongxing, Hu, Zhang-Zhi, ...

The Protein Information Resource (PIR) serves as an integrated public resource of functional annotation of protein data to support genomic/proteomic research and scientific discovery. The PIR, in...

The Protein Information Resource (PIR)

Barker, Winona C., Garavelli, John S., Huang, Hongzhan, McGarvey, Peter B., Orcutt, Bruce C., Srinivasarao, Geetha Y., ...

The Protein Information Resource (PIR) produces the largest, most comprehensive, annotated protein sequence database in the public domain, the PIR-International Protein Sequence Database, in...

Molecular evolution of eukaryotic genomes: hemiascomycetous yeast spliceosomal introns

Bon, Elisabeth, Casaregola, Serge, Blandin, Gaëlle, Llorente, Bertrand, Neuvéglise, Cécile, Munsterkotter, Martin, ...

As part of the exploratory sequencing program Génolevures, visual scrutinisation and bioinformatic tools were used to detect spliceosomal introns in seven hemiascomycetous yeast species. A total of...

The PEDANT genome database

Frishman, Dmitrij, Mokrejs, Martin, Kosykh, Denis, Kastenmüller, Gabi, Kolesov, Grigory, Zubrzycki, Igor, ...

The PEDANT genome database (http://pedant.gsf.de) provides exhaustive automatic analysis of genomic sequences by a large variety of established bioinformatics tools through a comprehensive Web-based...

Sputnik: a database platform for comparative plant genomics

Rudd, Stephen, Mewes, Hans-Werner, Mayer, Klaus F.X.

Two million plant ESTs, from 20 different plant species, and totalling more than one 1000 Mbp of DNA sequence, represents a formidable transcriptomic resource. Sputnik uses the potential of this...

MIPS Arabidopsis thaliana Database (MAtDB): an integrated biological knowledge resource for plant genomics

Schoof, Heiko, Ernst, Rebecca, Nazarov, Vladimir, Pfeifer, Lukas, Mewes, Hans-Werner, Mayer, Klaus F. X.

Arabidopsis thaliana is the most widely studied model plant. Functional genomics is intensively underway in many laboratories worldwide. Beyond the basic annotation of the primary sequence data, the...

Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs

Wiemann, Stefan, Weil, Bernd, Wellenreuther, Ruth, Gassenhuber, Johannes, Glassl, Sabine, Ansorge, Wilhelm, ...

With the complete human genomic sequence being unraveled, the focus will shift to gene identification and to the functional analysis of gene products. The generation of a set of cDNAs, both sequences...

Conservation of Microstructure between a Sequenced Region of the Genome of Rice and Multiple Segments of the Genome of Arabidopsis thaliana

Mayer, Klaus, Murphy, George, Tarchini, Renato, Wambutt, Rolf, Volckaert, Guido, Pohl, Thomas, ...

The nucleotide sequence was determined for a 340-kb segment of rice chromosome 2, revealing 56 putative protein-coding genes. This represents a density of one gene per 6.1 kb, which is higher than...

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

Imanishi, Tadashi, Itoh, Takeshi, Suzuki, Yutaka, O'Donovan, Claire, Fukuchi, Satoshi, Koyanagi, Kanako O, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

The PEDANT genome database in 2005

Riley, M. Louise, Schmidt, Thorsten, Wagner, Christian, Mewes, Hans-Werner, Frishman, Dmitrij

The PEDANT genome database (http://pedant.gsf.de) contains pre-computed bioinformatics analyses of publicly available genomes. Its main mission is to provide robust automatic annotation of the vast...

MPact: the MIPS protein interaction resource on yeast

Güldener, Ulrich, Münsterkötter, Martin, Oesterheld, Matthias, Pagel, Philipp, Ruepp, Andreas, Mewes, Hans-Werner, ...

In recent years, the Munich Information Center for Protein Sequences (MIPS) yeast protein–protein interaction (PPI) dataset has been used in numerous analyses of protein networks and has been...

FGDB: a comprehensive fungal genome resource on the plant pathogen Fusarium graminearum

Güldener, Ulrich, Mannhaupt, Gertrud, Münsterkötter, Martin, Haase, Dirk, Oesterheld, Matthias, Stümpflen, Volker, ...

The MIPS Fusarium graminearum Genome Database (FGDB) is a comprehensive genome database on one of the most devastating fungal plant pathogens of wheat and barley. FGDB provides information on two...

Spatiotemporal Expression Control Correlates with Intragenic Scaffold Matrix Attachment Regions (S/MARs) in Arabidopsis thaliana

Tetko, Igor V, Haberer, Georg, Rudd, Stephen, Meyers, Blake, Mewes, Hans-Werner, Mayer, Klaus F. X

Scaffold/matrix attachment regions (S/MARs) are essential for structural organization of the chromatin within the nucleus and serve as anchors of chromatin loop domains. A significant fraction of...

Protein Information Resource: a community resource for expert annotation of protein data

Barker, Winona C., Garavelli, John S., Hou, Zhenglin, Huang, Hongzhan, Ledley, Robert S., McGarvey, Peter B., ...

The Protein Information Resource, in collaboration with the Munich Information Center for Protein Sequences (MIPS) and the Japan International Protein Information Database (JIPID), produces the most...

The Protein Information Resource: an integrated public resource of functional annotation of proteins

Wu, Cathy H., Huang, Hongzhan, Arminski, Leslie, Castro-Alvear, Jorge, Chen, Yongxing, Hu, Zhang-Zhi, ...

The Protein Information Resource (PIR) serves as an integrated public resource of functional annotation of protein data to support genomic/proteomic research and scientific discovery. The PIR, in...

The Protein Information Resource (PIR)

Barker, Winona C., Garavelli, John S., Huang, Hongzhan, McGarvey, Peter B., Orcutt, Bruce C., Srinivasarao, Geetha Y., ...

The Protein Information Resource (PIR) produces the largest, most comprehensive, annotated protein sequence database in the public domain, the PIR-International Protein Sequence Database, in...

Molecular evolution of eukaryotic genomes: hemiascomycetous yeast spliceosomal introns

Bon, Elisabeth, Casaregola, Serge, Blandin, Gaëlle, Llorente, Bertrand, Neuvéglise, Cécile, Munsterkotter, Martin, ...

As part of the exploratory sequencing program Génolevures, visual scrutinisation and bioinformatic tools were used to detect spliceosomal introns in seven hemiascomycetous yeast species. A total of...

The PEDANT genome database

Frishman, Dmitrij, Mokrejs, Martin, Kosykh, Denis, Kastenmüller, Gabi, Kolesov, Grigory, Zubrzycki, Igor, ...

The PEDANT genome database (http://pedant.gsf.de) provides exhaustive automatic analysis of genomic sequences by a large variety of established bioinformatics tools through a comprehensive Web-based...

Sputnik: a database platform for comparative plant genomics

Rudd, Stephen, Mewes, Hans-Werner, Mayer, Klaus F.X.

Two million plant ESTs, from 20 different plant species, and totalling more than one 1000 Mbp of DNA sequence, represents a formidable transcriptomic resource. Sputnik uses the potential of this...

MIPS Arabidopsis thaliana Database (MAtDB): an integrated biological knowledge resource for plant genomics

Schoof, Heiko, Ernst, Rebecca, Nazarov, Vladimir, Pfeifer, Lukas, Mewes, Hans-Werner, Mayer, Klaus F. X.

Arabidopsis thaliana is the most widely studied model plant. Functional genomics is intensively underway in many laboratories worldwide. Beyond the basic annotation of the primary sequence data, the...

Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs

Wiemann, Stefan, Weil, Bernd, Wellenreuther, Ruth, Gassenhuber, Johannes, Glassl, Sabine, Ansorge, Wilhelm, ...

With the complete human genomic sequence being unraveled, the focus will shift to gene identification and to the functional analysis of gene products. The generation of a set of cDNAs, both sequences...

Conservation of Microstructure between a Sequenced Region of the Genome of Rice and Multiple Segments of the Genome of Arabidopsis thaliana

Mayer, Klaus, Murphy, George, Tarchini, Renato, Wambutt, Rolf, Volckaert, Guido, Pohl, Thomas, ...

The nucleotide sequence was determined for a 340-kb segment of rice chromosome 2, revealing 56 putative protein-coding genes. This represents a density of one gene per 6.1 kb, which is higher than...

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

Imanishi, Tadashi, Itoh, Takeshi, Suzuki, Yutaka, O'Donovan, Claire, Fukuchi, Satoshi, Koyanagi, Kanako O, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

The PEDANT genome database in 2005

Riley, M. Louise, Schmidt, Thorsten, Wagner, Christian, Mewes, Hans-Werner, Frishman, Dmitrij

The PEDANT genome database (http://pedant.gsf.de) contains pre-computed bioinformatics analyses of publicly available genomes. Its main mission is to provide robust automatic annotation of the vast...

MPact: the MIPS protein interaction resource on yeast

Güldener, Ulrich, Münsterkötter, Martin, Oesterheld, Matthias, Pagel, Philipp, Ruepp, Andreas, Mewes, Hans-Werner, ...

In recent years, the Munich Information Center for Protein Sequences (MIPS) yeast protein–protein interaction (PPI) dataset has been used in numerous analyses of protein networks and has been...

FGDB: a comprehensive fungal genome resource on the plant pathogen Fusarium graminearum

Güldener, Ulrich, Mannhaupt, Gertrud, Münsterkötter, Martin, Haase, Dirk, Oesterheld, Matthias, Stümpflen, Volker, ...

The MIPS Fusarium graminearum Genome Database (FGDB) is a comprehensive genome database on one of the most devastating fungal plant pathogens of wheat and barley. FGDB provides information on two...

Spatiotemporal Expression Control Correlates with Intragenic Scaffold Matrix Attachment Regions (S/MARs) in Arabidopsis thaliana

Tetko, Igor V, Haberer, Georg, Rudd, Stephen, Meyers, Blake, Mewes, Hans-Werner, Mayer, Klaus F. X

Scaffold/matrix attachment regions (S/MARs) are essential for structural organization of the chromatin within the nucleus and serve as anchors of chromatin loop domains. A significant fraction of...

PEDANT genome database: 10 years online

Riley, M. Louise, Schmidt, Thorsten, Artamonova, Irena I., Wagner, Christian, Volz, Andreas, Heumann, Klaus, ...

The PEDANT genome database provides exhaustive annotation of 468 genomes by a broad set of bioinformatics algorithms. We describe recent developments of the PEDANT Web server. The all-new Graphical...