Handan Kaygun

Developmental Control of Histone mRNA and dSLBP Synthesis during Drosophila Embryogenesis and the Role of dSLBP in Histone mRNA 3′ End Processing In Vivo

Lanzotti, David J., Kaygun, Handan, Yang, Xiao, Duronio, Robert J., Marzluff, William F.

In metazoans, the 3′ end of histone mRNA is not polyadenylated but instead ends with a stem-loop structure that is required for cell cycle-regulated expression. The sequence of the stem-loop in the...

SLBP is associated with histone mRNA on polyribosomes as a component of the histone mRNP

Whitfield, Michael L., Kaygun, Handan, Erkmann, Judith A., Dominski, Zbigniew, Marzluff, William F.

The stem–loop binding protein (SLBP) binds the 3′ end of histone mRNA and is present both in nucleus, and in the cytoplasm on the polyribosomes. SLBP participates in the processing of the histone...

Translation Termination Is Involved in Histone mRNA Degradation when DNA Replication Is Inhibited

Kaygun, Handan, Marzluff, William F.

The levels of replication-dependent histone mRNAs are coordinately regulated with DNA synthesis. A major regulatory step in histone mRNA metabolism is regulation of the half-life of histone mRNAs....

Developmental Control of Histone mRNA and dSLBP Synthesis during Drosophila Embryogenesis and the Role of dSLBP in Histone mRNA 3′ End Processing In Vivo

Lanzotti, David J., Kaygun, Handan, Yang, Xiao, Duronio, Robert J., Marzluff, William F.

In metazoans, the 3′ end of histone mRNA is not polyadenylated but instead ends with a stem-loop structure that is required for cell cycle-regulated expression. The sequence of the stem-loop in the...

SLBP is associated with histone mRNA on polyribosomes as a component of the histone mRNP

Whitfield, Michael L., Kaygun, Handan, Erkmann, Judith A., Dominski, Zbigniew, Marzluff, William F.

The stem–loop binding protein (SLBP) binds the 3′ end of histone mRNA and is present both in nucleus, and in the cytoplasm on the polyribosomes. SLBP participates in the processing of the histone...

Translation Termination Is Involved in Histone mRNA Degradation when DNA Replication Is Inhibited

Kaygun, Handan, Marzluff, William F.

The levels of replication-dependent histone mRNAs are coordinately regulated with DNA synthesis. A major regulatory step in histone mRNA metabolism is regulation of the half-life of histone mRNAs....