Hélène Tourrière

RasGAP-Associated Endoribonuclease G3BP: Selective RNA Degradation and Phosphorylation-Dependent Localization

Tourrière, Hélène, Gallouzi, Imed-eddine, Chebli, Karim, Capony, Jean Paul, Mouaikel, John, Van Der Geer, Peter, ...

Mitogen activation of mRNA decay pathways likely involves specific endoribonucleases, such as G3BP, a phosphorylation-dependent endoribonuclease that associates with RasGAP in dividing but not...

Control of Fetal Growth and Neonatal Survival by the RasGAP-Associated Endoribonuclease G3BP

Zekri, Latifa, Chebli, Karim, Tourrière, Hélène, Nielsen, Finn C., Hansen, Thomas V. O., Rami, Abdelhaq, ...

The regulation of mRNA stability plays a major role in the control of gene expression during cell proliferation, differentiation, and development. Here, we show that inactivation of the...

RasGAP-Associated Endoribonuclease G3BP: Selective RNA Degradation and Phosphorylation-Dependent Localization

Tourrière, Hélène, Gallouzi, Imed-eddine, Chebli, Karim, Capony, Jean Paul, Mouaikel, John, Van Der Geer, Peter, ...

Mitogen activation of mRNA decay pathways likely involves specific endoribonucleases, such as G3BP, a phosphorylation-dependent endoribonuclease that associates with RasGAP in dividing but not...

Control of Fetal Growth and Neonatal Survival by the RasGAP-Associated Endoribonuclease G3BP

Zekri, Latifa, Chebli, Karim, Tourrière, Hélène, Nielsen, Finn C., Hansen, Thomas V. O., Rami, Abdelhaq, ...

The regulation of mRNA stability plays a major role in the control of gene expression during cell proliferation, differentiation, and development. Here, we show that inactivation of the...

The RasGAP-associated endoribonuclease G3BP assembles stress granules

Tourrière, Hélène, Chebli, Karim, Zekri, Latifa, Courselaud, Brice, Blanchard, Jean Marie, Bertrand, Edouard, ...

Stress granules (SGs) are formed in the cytoplasm in response to various toxic agents, and are believed to play a critical role in the regulation of mRNA metabolism during stress. In SGs, mRNAs are...