Zhang, Yan, Romero, Hector, Salinas, Gustavo, Gladyshev, Vadim N
Abstract Background Selenocysteine (Sec) is co-translationally inserted into protein in response to UGA codons. It occurs in oxidoreductase active sites and often is catalytically superior to...
Zhang, Yan, Romero, Hector, Salinas, Gustavo, Gladyshev, Vadim
Background: Selenocysteine (Sec) is co-translationally inserted into protein in response to UGA codons. It occurs in oxidoreductase active sites and often is catalytically superior to cysteine (Cys)....
Lobanov, Alexey V., Gromer, Stephan, Salinas, Gustavo, Gladyshev, Vadim
Proteins containing the 21st amino acid selenocysteine (Sec) are present in the three domains of life. However, within lower eukaryotes, particularly parasitic protists, the dependence on the trace...
Salinas, Gustavo, Romero, Héctor, Xu, Xue-Ming, Carlson, Bradley A., Hatfield, Dolph L., Gladyshev, Vadim N.
The complete sequencing of genomes and the development of in silico methods for identification of genes encoding selenocysteine (Sec)-containing proteins have greatly contributed to shape our view on...
Selenoproteins in parasites (2006)
Salinas, Gustavo, Lobanov, Alexei V., Gladyshev, Vadim N.
Parasites, which cause an enormous burden in the population of the third world, are a diverse group of organisms, many of which are sensitive to oxidative stress imposed by their hosts. In recent...
Evolution of selenium utilization traits (2005)
Romero, Héctor, Zhang, Yan, Gladyshev, Vadim N, Salinas, Gustavo
Abstract Background The essential trace element selenium is used in a wide variety of biological processes. Selenocysteine (Sec), the 21st amino acid, is co-translationally incorporated into a...
Evolution of selenium utilization traits (2005)
Romero, Hector, Zhang, Yan, Gladyshev, Vadim, Salinas, Gustavo
Background: The essential trace element selenium is used in a wide variety of biological processes. Selenocysteine (Sec), the 21st amino acid, is co-translationally incorporated into a restricted set...
Echinococcus granulosus antigen 5 is closely related to proteases of the trypsin family.
Lorenzo, Carmen, Salinas, Gustavo, Brugnini, Andreina, Wernstedt, Christer, Hellman, Ulf, González-Sapienza, Gualberto
Antigen 5 (Ag5) is a dominant secreted component of the larval stage of Echinococcus granulosus, and is highly immunogenic in human infections. Although the diagnostic value of Ag5 has been...
Evolution of selenium utilization traits
Romero, Héctor, Zhang, Yan, Gladyshev, Vadim N, Salinas, Gustavo
Completely sequenced genomes were analyzed for occurrence of SelA, B, C, D and ybbB genes. SelB and SelC were found to be signatures for the Sec decoding trait, while SelD defines the overall...
Lobanov, Alexey V., Gromer, Stephan, Salinas, Gustavo, Gladyshev, Vadim N.
Proteins containing the 21st amino acid selenocysteine (Sec) are present in the three domains of life. However, within lower eukaryotes, particularly parasitic protists, the dependence on the trace...
Echinococcus granulosus antigen 5 is closely related to proteases of the trypsin family.
Lorenzo, Carmen, Salinas, Gustavo, Brugnini, Andreina, Wernstedt, Christer, Hellman, Ulf, González-Sapienza, Gualberto
Antigen 5 (Ag5) is a dominant secreted component of the larval stage of Echinococcus granulosus, and is highly immunogenic in human infections. Although the diagnostic value of Ag5 has been...
Evolution of selenium utilization traits
Romero, Héctor, Zhang, Yan, Gladyshev, Vadim N, Salinas, Gustavo
Completely sequenced genomes were analyzed for occurrence of SelA, B, C, D and ybbB genes. SelB and SelC were found to be signatures for the Sec decoding trait, while SelD defines the overall...
Lobanov, Alexey V., Gromer, Stephan, Salinas, Gustavo, Gladyshev, Vadim N.
Proteins containing the 21st amino acid selenocysteine (Sec) are present in the three domains of life. However, within lower eukaryotes, particularly parasitic protists, the dependence on the trace...
Zhang, Yan, Romero, Hector, Salinas, Gustavo, Gladyshev, Vadim N
Comparative genomics and evolutionary analyses to examine the dynamics of selenocysteine utilization in bacteria reveal a dynamic balance between selenoprotein origin and loss.