Gunnar B. Kristensen

GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data (2008)

Lyng, Heidi, Lando, Malin, Brøvig, Runar S, Svendsrud, Debbie H, Johansen, Morten, Galteland, Eivind, ...

Abstract Absolute tumor DNA copy numbers can currently be achieved only on a single gene basis by using fluorescence in situ hybridization (FISH). We present GeneCount, a method for genome-wide...

Metabolic mapping by use of high-resolution magic angle spinning 1H MR spectroscopy for assessment of apoptosis in cervical carcinomas (2007)

Lyng, Heidi, Sitter, Beathe, Bathen, Tone F, Jensen, Line R, Sundfør, Kolbein, Kristensen, Gunnar B, ...

Abstract Background High-resolution magic angle proton magnetic resonance spectroscopy (HR 1 H MAS MRS) provides a broad metabolic mapping of intact tumor samples and allows for microscopy...

Gene expressions and copy numbers associated with metastatic phenotypes of uterine cervical cancer (2006)

Lyng, Heidi, Brøvig, Runar S, Svendsrud, Debbie H, Holm, Ruth, Kaalhus, Olav, Knutstad, Kjetil, ...

Abstract Background A better understanding of the development of metastatic disease and the identification of molecular markers for cancer spread would be useful for the design of improved treatment...

Gene Expression Programs in Response to Hypoxia: Cell Type Specificity and Prognostic Significance in Human Cancers (2006)

Jen-Tsan Chi, Zhen Wang, Edwin H. Rodriguez, Marci E. Schaner, Ali Salim, ...

The transcriptional response to hypoxia varies between cell types. A gene-expression signature of the cellular response to hypoxia is associated with a significantly poorer prognosis in breast and...

Gene Expression Programs in Response to Hypoxia: Cell Type Specificity and Prognostic Significance in Human Cancers (2006)

Jen-Tsan Chi, Zhen Wang, Edwin H. Rodriguez, Marci E. Schaner, Ali Salim, ...

Background Inadequate oxygen (hypoxia) triggers a multifaceted cellular response that has important roles in normal physiology and in many human diseases. A transcription factor, hypoxia-inducible...

High sensitivity assays for docetaxel and paclitaxel in plasma using solid-phase extraction and high-performance liquid chromatography with UV detection (2006)

Andersen, Anders, Warren, David J, Brunsvig, Paal F, Aamdal, Steinar, Kristensen, Gunnar B, Olsen, Harald

Abstract Background The taxanes paclitaxel and docetaxel have traditionally been used in high doses every third week in the treatment of cancer. Lately there has been a trend towards giving weekly...

Variation in gene expression patterns in effusions and primary tumors from serous ovarian cancer patients (2005)

Schaner, Marci E, Davidson, Ben, Skrede, Martina, Reich, Reuven, Flørenes, Vivi, Risberg, Björn, ...

Abstract Background While numerous studies have characterized primary ovarian tumors, little information is available regarding expression patterns of metastatic sites of this cancer. To define sets...

Gene Expression Patterns in Ovarian Carcinomas

Schaner, Marci E., Ross, Douglas T., Ciaravino, Giuseppe, Sørlie, Therese, Troyanskaya, Olga, Diehn, Maximilian, ...

We used DNA microarrays to characterize the global gene expression patterns in surface epithelial cancers of the ovary. We identified groups of genes that distinguished the clear cell subtype from...

Gene Expression Programs in Response to Hypoxia: Cell Type Specificity and Prognostic Significance in Human Cancers

Chi, Jen-Tsan, Wang, Zhen, Nuyten, Dimitry S. A, Rodriguez, Edwin H, Schaner, Marci E, Salim, Ali, ...

The transcriptional response to hypoxia varies between cell types. A gene-expression signature of the cellular response to hypoxia is associated with a significantly poorer prognosis in breast and...

Presence of E6 and E7 mRNA from Human Papillomavirus Types 16, 18, 31, 33, and 45 in the Majority of Cervical Carcinomas

Kraus, Irene, Molden, Tor, Holm, Ruth, Lie, A. Kathrine, Karlsen, Frank, Kristensen, Gunnar B., ...

The oncogenic potential of the human papillomavirus (HPV) early genes E6 and E7 is well established and a source of interest with regard to HPV testing for cervical carcinoma. Here we present a study...

Gene Expression Patterns in Ovarian Carcinomas

Schaner, Marci E., Ross, Douglas T., Ciaravino, Giuseppe, Sørlie, Therese, Troyanskaya, Olga, Diehn, Maximilian, ...

We used DNA microarrays to characterize the global gene expression patterns in surface epithelial cancers of the ovary. We identified groups of genes that distinguished the clear cell subtype from...

Gene Expression Programs in Response to Hypoxia: Cell Type Specificity and Prognostic Significance in Human Cancers

Chi, Jen-Tsan, Wang, Zhen, Nuyten, Dimitry S. A, Rodriguez, Edwin H, Schaner, Marci E, Salim, Ali, ...

The transcriptional response to hypoxia varies between cell types. A gene-expression signature of the cellular response to hypoxia is associated with a significantly poorer prognosis in breast and...

Presence of E6 and E7 mRNA from Human Papillomavirus Types 16, 18, 31, 33, and 45 in the Majority of Cervical Carcinomas

Kraus, Irene, Molden, Tor, Holm, Ruth, Lie, A. Kathrine, Karlsen, Frank, Kristensen, Gunnar B., ...

The oncogenic potential of the human papillomavirus (HPV) early genes E6 and E7 is well established and a source of interest with regard to HPV testing for cervical carcinoma. Here we present a study...

Expressions of EphA2 and EphrinA-1 in early squamous cell cervical carcinomas and their relation to prognosis

Holm, Ruth, De Putte, Gregg Van, Suo, Zhenhe, Lie, A Kathrine, Kristensen, Gunnar B

By using immunohistochemistry we investigated the expression of EphA2 and EphrinA-1 in 217 early squamous cell cervical carcinomas and examine their prognostic relevance. For EphA2 expression, 21...

GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data

Lyng, Heidi, Lando, Malin, Brøvig, Runar S, Svendsrud, Debbie H, Johansen, Morten, Galteland, Eivind, ...

Absolute tumor DNA copy numbers can currently be achieved only on a single gene basis by using fluorescence in situ hybridization (FISH). We present GeneCount, a method for genome-wide calculation of...