Regions of Human Immunodeficiency Virus Type 1 nef Required for Function In Vivo
Aldrovandi, Grace M., Gao, Lianying, Bristol, Gregory, Zack, Jerome A.
In vivo studies in monkeys and humans have indicated that immunodeficiency viruses with Nef deleted are nonpathogenic in immunocompetent hosts, and this has motivated a search for live attenuated...
Thymic Dendritic Cells Are Primary Targets for the Oncogenic Virus SL3-3
Uittenbogaart, Christel H., Law, Wendy, Leenen, Pieter J. M., Bristol, Gregory, Van Ewijk, Willem, Hays, Esther F.
The murine retrovirus SL3-3 causes malignant transformation of thymocytes and thymic lymphoma in mice of the AKR and NFS strains when they are inoculated neonatally. The objective of the present...
Antibody-Directed Targeting of Retroviral Vectors via Cell Surface Antigens
Morizono, Kouki, Bristol, Gregory, Xie, Yi-ming, Kung, Sam Kam-Pun, Chen, Irvin S. Y.
Targeted stable transduction of specific cells is a highly desirable goal for gene therapy applications. We report an efficient and broadly applicable approach for targeting retroviral vectors to...
Regions of Human Immunodeficiency Virus Type 1 nef Required for Function In Vivo
Aldrovandi, Grace M., Gao, Lianying, Bristol, Gregory, Zack, Jerome A.
In vivo studies in monkeys and humans have indicated that immunodeficiency viruses with Nef deleted are nonpathogenic in immunocompetent hosts, and this has motivated a search for live attenuated...
Thymic Dendritic Cells Are Primary Targets for the Oncogenic Virus SL3-3
Uittenbogaart, Christel H., Law, Wendy, Leenen, Pieter J. M., Bristol, Gregory, Van Ewijk, Willem, Hays, Esther F.
The murine retrovirus SL3-3 causes malignant transformation of thymocytes and thymic lymphoma in mice of the AKR and NFS strains when they are inoculated neonatally. The objective of the present...
Antibody-Directed Targeting of Retroviral Vectors via Cell Surface Antigens
Morizono, Kouki, Bristol, Gregory, Xie, Yi-ming, Kung, Sam Kam-Pun, Chen, Irvin S. Y.
Targeted stable transduction of specific cells is a highly desirable goal for gene therapy applications. We report an efficient and broadly applicable approach for targeting retroviral vectors to...
Vatakis, Dimitrios N., Bristol, Gregory, Wilkinson, Thomas A., Chow, Samson A., Zack, Jerome A.
Unlike activated T cells, quiescent CD4+ T cells have shown resistance to human immunodeficiency virus (HIV) infection due to a block in the early events of the viral life cycle. To further...
Primary Cell Model for Activation-Inducible Human Immunodeficiency Virus▿
Burke, Bryan, Brown, Helen J., Marsden, Matthew D., Bristol, Gregory, Vatakis, Dimitrios N., Zack, Jerome A.
Quiescent T lymphocytes containing latent human immunodeficiency virus (HIV) provide a long-lived viral reservoir. This reservoir may be the source of active infection that is reinitiated following...