Involvement of P311 in the affective, but not in the sensory component of pain (2008)
Sun, Yan-Gang, Gao, Yong-Jing, Zhao, Zhong-Qiu, Huang, Bing, Yin, Jun, Taylor, Gregory A, ...
Abstract Pain is comprised of the sensory and affective components. Compared to the well-investigated mechanisms of the sensory pain, much less is known about the mechanisms underlying the affective...
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Pathogen-specific loss of host resistance in mice lacking the IFN-γ-inducible gene IGTP
Taylor, Gregory A., Collazo, Carmen M., Yap, George S., Nguyen, Khuong, Gregorio, Theresa A., Taylor, Lynn S., ...
Interferon-γ (IFN-γ) is critical for defense against pathogens, but the molecules that mediate its antimicrobial responses are largely unknown. IGTP is the prototype for a family of...
Koochekpour, Shahriar, Jeffers, Michael, Wang, Paul H., Gong, Changning, Taylor, Gregory A., Roessler, Lisa M., ...
Loss of function in the von Hippel-Lindau (VHL) tumor suppressor gene occurs in familial and most sporadic renal cell carcinomas (RCCs). VHL has been linked to the regulation of cell cycle cessation...
Gamma Interferon-Induced Inhibition of Toxoplasma gondii in Astrocytes Is Mediated by IGTP
Halonen, Sandra K., Taylor, Gregory A., Weiss, Louis M.
Toxoplasma gondii is an important pathogen in the central nervous system, causing a severe and often fatal encephalitis in patients with AIDS. Gamma interferon (IFN-γ) is the main cytokine...
Collazo, Carmen M., Yap, George S., Hieny, Sara, Caspar, Patricia, Feng, Carl G., Taylor, Gregory A., ...
IGTP is a member of the 47-kDa family of gamma interferon (IFN-γ)-induced GTPases. We have previously shown that IGTP is critical for host resistance to Toxoplasma gondii infection. In the present...
P311 induces a TGF-β1–independent, nonfibrogenic myofibroblast phenotype
Pan, Desi, Zhe, Xiaoning, Jakkaraju, Sandhya, Taylor, Gregory A., Schuger, Lucia
P311, also called PTZ17, was identified by suppressive subtraction hybridization as potentially involved in smooth muscle (SM) myogenesis. P311 is an 8-kDa protein with several PEST-like motifs found...
Gavrilescu, L. Cristina, Butcher, Barbara A., Del Rio, Laura, Taylor, Gregory A., Denkers, Eric Y.
The opportunistic protozoan Toxoplasma gondii is a prototypic Th1-inducing pathogen inducing strong gamma interferon (IFN-γ) cytokine responses that are required to survive infection. Intracellular...
p47 GTPases Regulate Toxoplasma gondii Survival in Activated Macrophages
Butcher, Barbara A., Greene, Robert I., Henry, Stanley C., Annecharico, Kimberly L., Weinberg, J. Brice, Denkers, Eric Y., ...
The cytokine gamma interferon (IFN-γ) is critical for resistance to Toxoplasma gondii. IFN-γ strongly activates macrophages and nonphagocytic host cells to limit intracellular growth of T. gondii;...
Pathogen-specific loss of host resistance in mice lacking the IFN-γ-inducible gene IGTP
Taylor, Gregory A., Collazo, Carmen M., Yap, George S., Nguyen, Khuong, Gregorio, Theresa A., Taylor, Lynn S., ...
Interferon-γ (IFN-γ) is critical for defense against pathogens, but the molecules that mediate its antimicrobial responses are largely unknown. IGTP is the prototype for a family of...
Koochekpour, Shahriar, Jeffers, Michael, Wang, Paul H., Gong, Changning, Taylor, Gregory A., Roessler, Lisa M., ...
Loss of function in the von Hippel-Lindau (VHL) tumor suppressor gene occurs in familial and most sporadic renal cell carcinomas (RCCs). VHL has been linked to the regulation of cell cycle cessation...
Gamma Interferon-Induced Inhibition of Toxoplasma gondii in Astrocytes Is Mediated by IGTP
Halonen, Sandra K., Taylor, Gregory A., Weiss, Louis M.
Toxoplasma gondii is an important pathogen in the central nervous system, causing a severe and often fatal encephalitis in patients with AIDS. Gamma interferon (IFN-γ) is the main cytokine...
Collazo, Carmen M., Yap, George S., Hieny, Sara, Caspar, Patricia, Feng, Carl G., Taylor, Gregory A., ...
IGTP is a member of the 47-kDa family of gamma interferon (IFN-γ)-induced GTPases. We have previously shown that IGTP is critical for host resistance to Toxoplasma gondii infection. In the present...
P311 induces a TGF-β1–independent, nonfibrogenic myofibroblast phenotype
Pan, Desi, Zhe, Xiaoning, Jakkaraju, Sandhya, Taylor, Gregory A., Schuger, Lucia
P311, also called PTZ17, was identified by suppressive subtraction hybridization as potentially involved in smooth muscle (SM) myogenesis. P311 is an 8-kDa protein with several PEST-like motifs found...
Gavrilescu, L. Cristina, Butcher, Barbara A., Del Rio, Laura, Taylor, Gregory A., Denkers, Eric Y.
The opportunistic protozoan Toxoplasma gondii is a prototypic Th1-inducing pathogen inducing strong gamma interferon (IFN-γ) cytokine responses that are required to survive infection. Intracellular...
p47 GTPases Regulate Toxoplasma gondii Survival in Activated Macrophages
Butcher, Barbara A., Greene, Robert I., Henry, Stanley C., Annecharico, Kimberly L., Weinberg, J. Brice, Denkers, Eric Y., ...
The cytokine gamma interferon (IFN-γ) is critical for resistance to Toxoplasma gondii. IFN-γ strongly activates macrophages and nonphagocytic host cells to limit intracellular growth of T. gondii;...
Bernstein-Hanley, Isaac, Coers, Jörn, Balsara, Zarine R., Taylor, Gregory A., Starnbach, Michael N., Dietrich, William F.
Infections caused by the bacteria Chlamydia trachomatis contribute to diverse pathologies in a variety of human populations. We previously used a systemic model of C. trachomatis infection in mice to...
Ling, Yun M., Shaw, Michael H., Ayala, Carol, Coppens, Isabelle, Taylor, Gregory A., Ferguson, David J.P., ...
Apicomplexan protozoan pathogens avoid destruction and establish a replicative niche within host cells by forming a nonfusogenic parasitophorous vacuole (PV). Here we present evidence for...
Collazo, Carmen M., Yap, George S., Sempowski, Gregory D., Lusby, Kimberly C., Tessarollo, Lino, Woude, George F. Vande, ...
The cytokine interferon (IFN)-γ regulates immune clearance of parasitic, bacterial, and viral infections; however, the underlying mechanisms are poorly understood. Recently, a family of...
Involvement of P311 in the affective, but not in the sensory component of pain
Sun, Yan-Gang, Gao, Yong-Jing, Zhao, Zhong-Qiu, Huang, Bing, Yin, Jun, Taylor, Gregory A, ...
Pain is comprised of the sensory and affective components. Compared to the well-investigated mechanisms of the sensory pain, much less is known about the mechanisms underlying the affective pain. In...