Graham R. Foster

Dengue virus inhibits interferon-α signaling by reducing STAT2 expression (2005)

Jones, Meleri, Davidson, Andrew, Hibbert, Linda, Gruenwald, Petra, Schlaak, Joerg, Ball, Simon, ...

Type 1 interferons (IFN-α/β) are key mediators of innate antiviral responses but have little effect on established replication of dengue viruses, which are mosquito-borne flaviviruses of immense...

Dengue Virus Inhibits Alpha Interferon Signaling by Reducing STAT2 Expression

Jones, Meleri, Davidson, Andrew, Hibbert, Linda, Gruenwald, Petra, Schlaak, Joerg, Ball, Simon, ...

Alpha/beta interferon (IFN-α/β) is a key mediator of innate antiviral responses but has little effect on the established replication of dengue viruses, which are mosquito-borne flaviviruses of...

Dengue Virus Inhibits Alpha Interferon Signaling by Reducing STAT2 Expression

Jones, Meleri, Davidson, Andrew, Hibbert, Linda, Gruenwald, Petra, Schlaak, Joerg, Ball, Simon, ...

Alpha/beta interferon (IFN-α/β) is a key mediator of innate antiviral responses but has little effect on the established replication of dengue viruses, which are mosquito-borne flaviviruses of...

Qualitatively distinct patterns of cytokines are released by human dendritic cells in response to different pathogens

Scott, Karen, Manunta, Maria, Germain, Conrad, Smith, Peter, Jones, Meleri, Mitchell, Peter, ...

Dendritic cells produce cytokines that regulate the class of the adaptive immune response. Microbial recognition is mediated, at least in part, by pattern recognition receptors such as Toll-like...

Contribution of alcohol to deaths in road traffic accidents in Tayside 1982-6

Foster, Graham R, Dunbar, James A, Whittet, David, Fernando, Gyan C A

In Britain the precise number and relative proportions of deaths among drivers, passengers, and pedestrians in road traffic accidents related to alcohol are not known. These data were obtained in...

Chronic Exposure to Helicobacter pylori Impairs Dendritic Cell Function and Inhibits Th1 Development▿

Mitchell, Peter, Germain, Conrad, Fiori, Pier Luigi, Khamri, Wafa, Foster, Graham R., Ghosh, Subrata, ...

Helicobacter pylori causes chronic gastric infection that affects the majority of the world's population. Despite generating an inflammatory response, the immune system usually fails to clear the...

Directed evolution of gene-shuffled IFN-α molecules with activity profiles tailored for treatment of chronic viral diseases

Brideau-Andersen, Amy D., Huang, Xiaojian, Sun, Siu-Chi Chang, Chen, Teddy T., Stark, Diane, Sas, Ian J., ...

Type I IFNs are unusually pleiotropic cytokines that bind to a single heterodimeric receptor and have potent antiviral, antiproliferative, and immune modulatory activities. The diverse effects of the...

Telomere Erosion in Memory T Cells Induced by Telomerase Inhibition at the Site of Antigenic Challenge In Vivo

Reed, John R., Vukmanovic-Stejic, Milica, Fletcher, Jean M., Soares, Maria Vieira D., Cook, Joanne E., Orteu, Catherine H., ...

The extent of human memory T cell proliferation, differentiation, and telomere erosion that occurs after a single episode of immune challenge in vivo is unclear. To investigate this, we injected...

Contribution of alcohol to deaths in road traffic accidents in Tayside 1982-6

Foster, Graham R, Dunbar, James A, Whittet, David, Fernando, Gyan C A

In Britain the precise number and relative proportions of deaths among drivers, passengers, and pedestrians in road traffic accidents related to alcohol are not known. These data were obtained in...