Gerard Manning

The Sorcerer II Global Ocean Sampling Expedition: Expanding the Universe of Protein Families (2007)

Shibu Yooseph, Granger Sutton, Douglas B. Rusch, Aaron L. Halpern, Shannon J. Williamson, Karin Remington, ...

Metagenomics projects based on shotgun sequencing of populations of micro-organisms yield insight into protein families. We used sequence similarity clustering to explore proteins with a...

Structural and Functional Diversity of the Microbial Kinome (2007)

Natarajan Kannan, Susan S. Taylor, Yufeng Zhai, J. Craig Venter, Gerard Manning

The eukaryotic protein kinase (ePK) domain mediates the majority of signaling and coordination of complex events in eukaryotes. By contrast, most bacterial signaling is thought to occur through...

Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote. (2006)

Eisen, Jonathan A, Coyne, Robert S, Wu, Martin, Wu, Dongying, Thiagarajan, Mathangi, Wortman, Jennifer R, ...

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct...

Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote (2006)

Jonathan A. Eisen, Robert S. Coyne, Martin Wu, Dongying Wu, Mathangi Thiagarajan, Jennifer R. Wortman, ...

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct...

The Dictyostelium Kinome—Analysis of the Protein Kinases from a Simple Model Organism (2006)

Jonathan M. Goldberg, Gerard Manning, Allen Liu, Petra Fey, Karen E. Pilcher, Yanji Xu, ...

Dictyostelium discoideum is a widely studied model organism with both unicellular and multicellular forms in its developmental cycle. The Dictyostelium genome encodes 285 predicted protein kinases,...

Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote (2006)

Eisen, Jonathan A., Coyne, Robert S., Wu, Martin, Wu, Dongying, Thiagarajan, Mathangi, Wortman, Jennifer R., ...

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct...

Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote (2006)

Eisen, Jonathan A., Coyne, Robert S., Wu, Martin, Wu, Dongying, Thiagarajan, Mathangi, Wortman, Jennifer R., ...

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct...

The STE20 Kinase HGK Is Broadly Expressed in Human Tumor Cells and Can Modulate Cellular Transformation, Invasion, and Adhesion

Wright, Jocelyn H., Wang, Xueyan, Manning, Gerard, LaMere, Brandon J., Le, Phuong, Zhu, Shirley, ...

HGK (hepatocyte progenitor kinase-like/germinal center kinase-like kinase) is a member of the human STE20/mitogen-activated protein kinase kinase kinase kinase family of serine/threonine kinases and...

The mouse kinome: Discovery and comparative genomics of all mouse protein kinases

Caenepeel, Sean, Charydczak, Glen, Sudarsanam, Sucha, Hunter, Tony, Manning, Gerard

We have determined the full protein kinase (PK) complement (kinome) of mouse. This set of 540 genes includes many novel kinases and corrections or extensions to >150 published sequences. The mouse...

The Dictyostelium Kinome—Analysis of the Protein Kinases from a Simple Model Organism

Goldberg, Jonathan M, Manning, Gerard, Liu, Allen, Fey, Petra, Pilcher, Karen E, Xu, Yanji, ...

Dictyostelium discoideum is a widely studied model organism with both unicellular and multicellular forms in its developmental cycle. The Dictyostelium genome encodes 285 predicted protein kinases,...

Members of the NIMA-related Kinase Family Promote Disassembly of Cilia by Multiple Mechanisms

Wloga, Dorota, Camba, Amy, Rogowski, Krzysztof, Manning, Gerard, Jerka-Dziadosz, Maria, Gaertig, Jacek

The genome of Tetrahymena thermophila contains 39 loci encoding NIMA-related kinases (NRKs), an extraordinarily large number for a unicellular organism. Evolutionary analyses grouped these sequences...

Mutational Alteration of Human Immunodeficiency Virus Type 1 Vif Allows for Functional Interaction with Nonhuman Primate APOBEC3G†

Schröfelbauer, Bärbel, Senger, Tilo, Manning, Gerard, Landau, Nathaniel R.

Human APOBEC3F (hA3F) and APOBEC3G (hA3G) are antiretroviral cytidine deaminases that can be encapsidated during virus assembly to catalyze C→U deamination of the viral reverse transcripts in the...

Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote

Eisen, Jonathan A, Coyne, Robert S, Wu, Martin, Wu, Dongying, Thiagarajan, Mathangi, Wortman, Jennifer R, ...

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct...

The STE20 Kinase HGK Is Broadly Expressed in Human Tumor Cells and Can Modulate Cellular Transformation, Invasion, and Adhesion

Wright, Jocelyn H., Wang, Xueyan, Manning, Gerard, LaMere, Brandon J., Le, Phuong, Zhu, Shirley, ...

HGK (hepatocyte progenitor kinase-like/germinal center kinase-like kinase) is a member of the human STE20/mitogen-activated protein kinase kinase kinase kinase family of serine/threonine kinases and...

The mouse kinome: Discovery and comparative genomics of all mouse protein kinases

Caenepeel, Sean, Charydczak, Glen, Sudarsanam, Sucha, Hunter, Tony, Manning, Gerard

We have determined the full protein kinase (PK) complement (kinome) of mouse. This set of 540 genes includes many novel kinases and corrections or extensions to >150 published sequences. The mouse...

The Dictyostelium Kinome—Analysis of the Protein Kinases from a Simple Model Organism

Goldberg, Jonathan M, Manning, Gerard, Liu, Allen, Fey, Petra, Pilcher, Karen E, Xu, Yanji, ...

Dictyostelium discoideum is a widely studied model organism with both unicellular and multicellular forms in its developmental cycle. The Dictyostelium genome encodes 285 predicted protein kinases,...

Mutational Alteration of Human Immunodeficiency Virus Type 1 Vif Allows for Functional Interaction with Nonhuman Primate APOBEC3G†

Schröfelbauer, Bärbel, Senger, Tilo, Manning, Gerard, Landau, Nathaniel R.

Human APOBEC3F (hA3F) and APOBEC3G (hA3G) are antiretroviral cytidine deaminases that can be encapsidated during virus assembly to catalyze C→U deamination of the viral reverse transcripts in the...

Members of the NIMA-related Kinase Family Promote Disassembly of Cilia by Multiple Mechanisms

Wloga, Dorota, Camba, Amy, Rogowski, Krzysztof, Manning, Gerard, Jerka-Dziadosz, Maria, Gaertig, Jacek

The genome of Tetrahymena thermophila contains 39 loci encoding NIMA-related kinases (NRKs), an extraordinarily large number for a unicellular organism. Evolutionary analyses grouped these sequences...

Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote

Eisen, Jonathan A, Coyne, Robert S, Wu, Martin, Wu, Dongying, Thiagarajan, Mathangi, Wortman, Jennifer R, ...

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct...

The Sorcerer II Global Ocean Sampling Expedition: Expanding the Universe of Protein Families

Yooseph, Shibu, Sutton, Granger, Rusch, Douglas B, Halpern, Aaron L, Williamson, Shannon J, Remington, Karin, ...

Metagenomics projects based on shotgun sequencing of populations of micro-organisms yield insight into protein families. We used sequence similarity clustering to explore proteins with a...

Structural and Functional Diversity of the Microbial Kinome

Kannan, Natarajan, Taylor, Susan S, Zhai, Yufeng, Venter, J. Craig, Manning, Gerard

The eukaryotic protein kinase (ePK) domain mediates the majority of signaling and coordination of complex events in eukaryotes. By contrast, most bacterial signaling is thought to occur through...

Embryonic development of the Drosophila tracheal system /

Manning, Gerard.

Submitted to the Department of Biochemistry and the Committee on Graduate Studies of Stanford University.