George Demetri

Effects of ligand activation of peroxisome proliferator-activated receptor γ in human prostate cancer

Mueller, Elisabetta, Smith, Matthew, Sarraf, Pasha, Kroll, Todd, Aiyer, Anita, Kaufman, Donald S., ...

Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear hormone receptor that plays a key role in the differentiation of adipocytes. Activation of this receptor in liposarcomas and breast...

Effects of ligand activation of peroxisome proliferator-activated receptor γ in human prostate cancer

Mueller, Elisabetta, Smith, Matthew, Sarraf, Pasha, Kroll, Todd, Aiyer, Anita, Kaufman, Donald S., ...

Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear hormone receptor that plays a key role in the differentiation of adipocytes. Activation of this receptor in liposarcomas and breast...

KIT Extracellular and Kinase Domain Mutations in Gastrointestinal Stromal Tumors

Lux, Marcia L., Rubin, Brian P., Biase, Tara L., Chen, Chang-Jie, Maclure, Timothy, Demetri, George, ...

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms arising in the gastrointestinal tract. GISTs express the KIT receptor tyrosine kinase, and many cases have activating...