Georg F. Beilhack

The role of TNF-α in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: Analysis of dendritic cell maturation

Lee, Li-Fen, Xu, Baohui, Michie, Sara A., Beilhack, Georg F., Warganich, Tibor, Turley, Shannon, ...

TNF-α has been linked to the development of type 1 diabetes (T1D). We previously reported that neonatal treatment of nonobese diabetic (NOD) mice with TNF-α accelerated the onset of T1D, whereas...

The role of TNF-α in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: Analysis of dendritic cell maturation

Lee, Li-Fen, Xu, Baohui, Michie, Sara A., Beilhack, Georg F., Warganich, Tibor, Turley, Shannon, ...

TNF-α has been linked to the development of type 1 diabetes (T1D). We previously reported that neonatal treatment of nonobese diabetic (NOD) mice with TNF-α accelerated the onset of T1D, whereas...

Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes

Chaparro, Rodolfo José, Konigshofer, Yves, Beilhack, Georg F., Shizuru, Judith A., McDevitt, Hugh O., Chien, Yueh-hsiu

Before the onset of autoimmune destruction, type 1 diabetic patients and an animal model, the nonobese diabetic (NOD) mouse, show morphological and functional abnormalities in target organs, which...

In vivo analyses of early events in acute graft-versus-host disease reveal sequential infiltration of T-cell subsets

Beilhack, Andreas, Schulz, Stephan, Baker, Jeanette, Beilhack, Georg F., Wieland, Courtney B., Herman, Edward I., ...

Graft-versus-host disease (GVHD) is a major obstacle in allogeneic hematopoietic cell transplantation. Given the dynamic changes in immune cell subsets and tissue organization, which occur in GVHD,...