Gavin Brooks

The Coronavirus Infectious Bronchitis Virus Nucleoprotein Localizes to the Nucleolus

Hiscox, Julian A., Wurm, Torsten, Wilson, Louise, Britton, Paul, Cavanagh, David, Brooks, Gavin

The coronavirus nucleoprotein (N) has been reported to be involved in various aspects of virus replication. We examined by confocal microscopy the subcellular localization of the avian infectious...

Localization to the Nucleolus Is a Common Feature of Coronavirus Nucleoproteins, and the Protein May Disrupt Host Cell Division

Wurm, Torsten, Chen, Hongying, Hodgson, Teri, Britton, Paul, Brooks, Gavin, Hiscox, Julian A.

The subcellular localization of transmissible gastroenteritis virus (TGEV) and mouse hepatitis virus (MHV) (group I and group II coronaviruses, respectively) nucleoproteins (N proteins) were examined...

Interaction of the Coronavirus Nucleoprotein with Nucleolar Antigens and the Host Cell

Chen, Hongying, Wurm, Torsten, Britton, Paul, Brooks, Gavin, Hiscox, Julian A.

Coronavirus nucleoproteins (N proteins) localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N...

Forced expression of the cyclin B1–CDC2 complex induces proliferation in adult rat cardiomyocytes

Bicknell, Katrina A., Coxon, Carmen H., Brooks, Gavin

Repair of the mature mammalian myocardium following injury is impaired by the inability of the majority of cardiomyocytes to undergo cell division. We show that overexpression of the cyclin B1–CDC2...

Cell Cycle Perturbations Induced by Infection with the Coronavirus Infectious Bronchitis Virus and Their Effect on Virus Replication

Dove, Brian, Brooks, Gavin, Bicknell, Katrina, Wurm, Torsten, Hiscox, Julian A.

In eukaryotic cells, cell growth and division occur in a stepwise, orderly fashion described by a process known as the cell cycle. The relationship between positive-strand RNA viruses and the cell...

The Coronavirus Infectious Bronchitis Virus Nucleoprotein Localizes to the Nucleolus

Hiscox, Julian A., Wurm, Torsten, Wilson, Louise, Britton, Paul, Cavanagh, David, Brooks, Gavin

The coronavirus nucleoprotein (N) has been reported to be involved in various aspects of virus replication. We examined by confocal microscopy the subcellular localization of the avian infectious...

Localization to the Nucleolus Is a Common Feature of Coronavirus Nucleoproteins, and the Protein May Disrupt Host Cell Division

Wurm, Torsten, Chen, Hongying, Hodgson, Teri, Britton, Paul, Brooks, Gavin, Hiscox, Julian A.

The subcellular localization of transmissible gastroenteritis virus (TGEV) and mouse hepatitis virus (MHV) (group I and group II coronaviruses, respectively) nucleoproteins (N proteins) were examined...

Interaction of the Coronavirus Nucleoprotein with Nucleolar Antigens and the Host Cell

Chen, Hongying, Wurm, Torsten, Britton, Paul, Brooks, Gavin, Hiscox, Julian A.

Coronavirus nucleoproteins (N proteins) localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N...

Forced expression of the cyclin B1–CDC2 complex induces proliferation in adult rat cardiomyocytes

Bicknell, Katrina A., Coxon, Carmen H., Brooks, Gavin

Repair of the mature mammalian myocardium following injury is impaired by the inability of the majority of cardiomyocytes to undergo cell division. We show that overexpression of the cyclin B1–CDC2...

Cell Cycle Perturbations Induced by Infection with the Coronavirus Infectious Bronchitis Virus and Their Effect on Virus Replication

Dove, Brian, Brooks, Gavin, Bicknell, Katrina, Wurm, Torsten, Hiscox, Julian A.

In eukaryotic cells, cell growth and division occur in a stepwise, orderly fashion described by a process known as the cell cycle. The relationship between positive-strand RNA viruses and the cell...

Regulation of Cell Cycle and Stress Responses to Hydrostatic Pressure in Fission Yeast

George, Vinoj T., Brooks, Gavin, Humphrey, Timothy C.

We have investigated the cellular responses to hydrostatic pressure by using the fission yeast Schizosaccharomyces pombe as a model system. Exposure to sublethal levels of hydrostatic pressure...