Gagik Oganesyan

Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-kappa B activation pathways (2004)

Zarnegar, Brian, He, Jeannie Q., Oganesyan, Gagik, Hoffmann, Alexander, Baltimore, David, Cheng, Genhong

B lymphocytes can be activated by many different stimuli. However, the mechanisms responsible for the signaling and functional specificities of individual stimuli remain to be elucidated. Here, we...

Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-κB activation pathways

Zarnegar, Brian, He, Jeannie Q., Oganesyan, Gagik, Hoffmann, Alexander, Baltimore, David, Cheng, Genhong

B lymphocytes can be activated by many different stimuli. However, the mechanisms responsible for the signaling and functional specificities of individual stimuli remain to be elucidated. Here, we...

Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-κB activation pathways

Zarnegar, Brian, He, Jeannie Q., Oganesyan, Gagik, Hoffmann, Alexander, Baltimore, David, Cheng, Genhong

B lymphocytes can be activated by many different stimuli. However, the mechanisms responsible for the signaling and functional specificities of individual stimuli remain to be elucidated. Here, we...

Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif

Saha, Supriya K, Pietras, Eric M, He, Jeannie Q, Kang, Jason R, Liu, Su-Yang, Oganesyan, Gagik, ...

Upon recognition of viral infection, RIG-I and Helicard recruit a newly identified adapter termed Cardif, which induces type I interferon (IFN)-mediated antiviral responses through an unknown...

Rescue of TRAF3-null mice by p100 NF-κB deficiency

He, Jeannie Q., Zarnegar, Brian, Oganesyan, Gagik, Saha, Supriya K., Yamazaki, Soh, Doyle, Sean E., ...

Proper activation of nuclear factor (NF)–κB transcription factors is critical in regulating fundamental biological processes such as cell survival and proliferation, as well as in inflammatory and...