Frederik J. van Schooten

The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung (2005)

Albrecht, Catrin, Knaapen, Ad M, Becker, Andrea, Höhr, Doris, Haberzettl, Petra, Van Schooten, Frederik J, ...

Abstract Persistent inflammation and associated excessive oxidative stress have been crucially implicated in quartz-induced pulmonary diseases, including fibrosis and cancer. We have investigated the...

Application of four dyes in gene expression analyses by microarrays (2005)

Staal, Yvonne CM, Van Herwijnen, Marcel HM, Van Schooten, Frederik J, Van Delft, Joost HM

Abstract Background DNA microarrays are widely used in gene expression analyses. To increase throughput and minimize costs without reducing gene expression data obtained, we investigated whether four...

Application of four dyes in gene expression analyses by microarrays

Staal, Yvonne CM, Van Herwijnen, Marcel HM, Van Schooten, Frederik J, Van Delft, Joost HM

The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung

Albrecht, Catrin, Knaapen, Ad M, Becker, Andrea, Höhr, Doris, Haberzettl, Petra, Van Schooten, Frederik J, ...

Persistent inflammation and associated excessive oxidative stress have been crucially implicated in quartz-induced pulmonary diseases, including fibrosis and cancer. We have investigated the...

Application of four dyes in gene expression analyses by microarrays

Staal, Yvonne CM, Van Herwijnen, Marcel HM, Van Schooten, Frederik J, Van Delft, Joost HM

The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung

Albrecht, Catrin, Knaapen, Ad M, Becker, Andrea, Höhr, Doris, Haberzettl, Petra, Van Schooten, Frederik J, ...

Persistent inflammation and associated excessive oxidative stress have been crucially implicated in quartz-induced pulmonary diseases, including fibrosis and cancer. We have investigated the...

Chronic Exposure to the Carcinogenic Compound Benzo[a]Pyrene Induces Larger and Phenotypically Different Atherosclerotic Plaques in ApoE-Knockout Mice

Curfs, Daniëlle M. J., Lutgens, Esther, Gijbels, Marion J. J., Kockx, Mark M., Van Schooten, Frederik J.

Benzo[a]pyrene (B[a]P) is a polycyclic aromatic hydrocarbon with atherogenic and carcinogenic properties. The role of B[a]P in carcinogenesis is well established, and thought to exert via enzymatic...

Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location

Yauk, Carole, Polyzos, Aris, Rowan-Carroll, Andrea, Somers, Christopher M., Godschalk, Roger W., Van Schooten, Frederik J., ...

Particulate air pollution is widespread, yet we have little understanding of the long-term health implications associated with exposure. We investigated DNA damage, mutation, and methylation in...