Calcineurin activation influences muscle phenotype in a muscle-specific fashion (2004)
Talmadge, Robert J, Otis, Jeffrey S, Rittler, Matthew R, Garcia, Nicole D, Spencer, Shelly R, Lees, Simon J, ...
Abstract Background The calcium activated protein phosphatase 2B, also known as calcineurin, has been implicated as a cell signaling molecule involved with transduction of physiological signals (free...
Mutoh, Hiroyuki, Fung, Brenda P., Naya, Francisco J., Tsai, Ming-Jer, Nishitani, Junko, Leiter, Andrew B.
The gene encoding the hormone secretin is expressed only in enteroendocrine S cells and insulin-producing pancreatic β cells during development. A 120-bp enhancer directs cell-specific expression of...
Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway
Wu, Hai, Rothermel, Beverly, Kanatous, Shane, Rosenberg, Paul, Naya, Francisco J., Shelton, John M., ...
Gene expression in skeletal muscles of adult vertebrates is altered profoundly by changing patterns of contractile work. Here we observed that the functional activity of MEF2 transcription factors is...
MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type
Wu, Hai, Naya, Francisco J., McKinsey, Timothy A., Mercer, Brian, Shelton, John M., Chin, Eva R., ...
Different patterns of motor nerve activity drive distinctive programs of gene transcription in skeletal muscles, thereby establishing a high degree of metabolic and physiological specialization among...
CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo
Passier, Robert, Zeng, Hong, Frey, Norbert, Naya, Francisco J., Nicol, Rebekka L., McKinsey, Timothy A., ...
Hypertrophic growth is an adaptive response of the heart to diverse pathological stimuli and is characterized by cardiomyocyte enlargement, sarcomere assembly, and activation of a fetal program of...
Naya, Francisco J., Huang, Hsiang-Po, Qiu, Yuhong, Mutoh, Hiroyuki, DeMayo, Francesco J., Leiter, Andrew B., ...
Candidate transcription factors involved in pancreatic endocrine development have been isolated using insulin gene regulation as a paradigm. The cell-type restricted basic helix–loop–helix (bHLH)...
Mutoh, Hiroyuki, Naya, Francisco J., Tsai, Ming-Jer, Leiter, Andrew B.
The major epithelial cell types lining the intestine comprise a perpetually self-renewing population of cells that differentiate continuously from a stem cell in the intestinal crypts....
Calcineurin activation influences muscle phenotype in a muscle-specific fashion
Talmadge, Robert J, Otis, Jeffrey S, Rittler, Matthew R, Garcia, Nicole D, Spencer, Shelly R, Lees, Simon J, ...
Mutoh, Hiroyuki, Fung, Brenda P., Naya, Francisco J., Tsai, Ming-Jer, Nishitani, Junko, Leiter, Andrew B.
The gene encoding the hormone secretin is expressed only in enteroendocrine S cells and insulin-producing pancreatic β cells during development. A 120-bp enhancer directs cell-specific expression of...
Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway
Wu, Hai, Rothermel, Beverly, Kanatous, Shane, Rosenberg, Paul, Naya, Francisco J., Shelton, John M., ...
Gene expression in skeletal muscles of adult vertebrates is altered profoundly by changing patterns of contractile work. Here we observed that the functional activity of MEF2 transcription factors is...
MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type
Wu, Hai, Naya, Francisco J., McKinsey, Timothy A., Mercer, Brian, Shelton, John M., Chin, Eva R., ...
Different patterns of motor nerve activity drive distinctive programs of gene transcription in skeletal muscles, thereby establishing a high degree of metabolic and physiological specialization among...
CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo
Passier, Robert, Zeng, Hong, Frey, Norbert, Naya, Francisco J., Nicol, Rebekka L., McKinsey, Timothy A., ...
Hypertrophic growth is an adaptive response of the heart to diverse pathological stimuli and is characterized by cardiomyocyte enlargement, sarcomere assembly, and activation of a fetal program of...
Naya, Francisco J., Huang, Hsiang-Po, Qiu, Yuhong, Mutoh, Hiroyuki, DeMayo, Francesco J., Leiter, Andrew B., ...
Candidate transcription factors involved in pancreatic endocrine development have been isolated using insulin gene regulation as a paradigm. The cell-type restricted basic helix–loop–helix (bHLH)...
Mutoh, Hiroyuki, Naya, Francisco J., Tsai, Ming-Jer, Leiter, Andrew B.
The major epithelial cell types lining the intestine comprise a perpetually self-renewing population of cells that differentiate continuously from a stem cell in the intestinal crypts....