Abba, Martin C, Hu, Yuhui, Levy, Carla C, Gaddis, Sally, Kittrell, Frances S, Zhang, Yun, ...
Abstract Background The rexinoid bexarotene (LGD1069, Targretin) is a highly selective retinoid × receptor (RXR) agonist that inhibits the growth of pre-malignant and malignant breast cells....
Hormone-induced protection of mammary tumorigenesis in genetically engineered mouse models (2007)
Rajkumar, Lakshmanaswamy, Kittrell, Frances S, Guzman, Raphael C, Brown, Powel H, Nandi, Satyabrata, Medina, Daniel
Abstract Introduction The experiments reported here address the question of whether a short-term hormone treatment can prevent mammary tumorigenesis in two different genetically engineered mouse...
Unni, Emmanual, Kittrell, Frances S, Singh, Uma, Sinha, Raghu
Abstract Background Se-methylselenocysteine (MSC) is a naturally occurring organoselenium compound that inhibits mammary tumorigenesis in laboratory animals and in cell culture models. Previously we...
Hormone-induced protection of mammary tumorigenesis in genetically engineered mouse models
Rajkumar, Lakshmanaswamy, Kittrell, Frances S, Guzman, Raphael C, Brown, Powel H, Nandi, Satyabrata, Medina, Daniel
Kuperwasser, Charlotte, Hurlbut, Gregory D., Kittrell, Frances S., Dickinson, Ellen S., Laucirica, Rudy, Medina, Daniel, ...
Breast cancer is the most frequent tumor type among women in the United States and in individuals with Li-Fraumeni syndrome. The p53 tumor suppressor gene is altered in a large proportion of both...