Protean agonism at histamine H3 receptors in vitro and in vivo
Gbahou, Florence, Rouleau, Agnès, Morisset, Séverine, Parmentier, Régis, Crochet, Sylvain, Lin, Jian-Sheng, ...
G protein-coupled receptors (GPCRs) are allosteric proteins that adopt inactive (R) and active (R*) conformations in equilibrium. R* is promoted by agonists or occurs spontaneously, leading to...
Protean agonism at histamine H3 receptors in vitro and in vivo
Gbahou, Florence, Rouleau, Agnès, Morisset, Séverine, Parmentier, Régis, Crochet, Sylvain, Lin, Jian-Sheng, ...
G protein-coupled receptors (GPCRs) are allosteric proteins that adopt inactive (R) and active (R*) conformations in equilibrium. R* is promoted by agonists or occurs spontaneously, leading to...
Gbahou, Florence, Vincent, Ludwig, Humbert-Claude, Marie, Tardivel-Lacombe, Joel, Chabret, Claude, Arrang, Jean-Michel
Various histamine derivatives were investigated at the human H3 receptor (H3R) and H4 receptor (H4R) stably expressed in human embryonic kidney (HEK)-293 cells using [125I]iodoproxyfan and...