Severe B Cell Deficiency in Mice Lacking the Tec Kinase Family Members Tec and Btk (2000)
Ellmeier, Wilfried, Jung, Steffen, Sunshine, Mary Jean, Hatam, Farah, Xu, Yang, Baltimore, David, ...
Repression of interleukin-4 in T helper type 1 cells by Runx/Cbfβ binding to the Il4 silencer
Naoe, Yoshinori, Setoguchi, Ruka, Akiyama, Kaori, Muroi, Sawako, Kuroda, Masahiko, Hatam, Farah, ...
Interferon γ (IFNγ) is the hallmark cytokine produced by T helper type 1 (Th1) cells, whereas interleukin (IL)-4 is the hallmark cytokine produced by Th2 cells. Although previous studies have...
Severe B Cell Deficiency in Mice Lacking the Tec Kinase Family Members Tec and Btk
Ellmeier, Wilfried, Jung, Steffen, Sunshine, Mary Jean, Hatam, Farah, Xu, Yang, Baltimore, David, ...
The cytoplasmic protein tyrosine kinase Tec has been proposed to have important functions in hematopoiesis and lymphocyte signal transduction. Here we show that Tec-deficient mice developed normally...