Fabio Grizzi

Usefulness of cancer-testis antigens as biomarkers for the diagnosis and treatment of hepatocellular carcinoma (2007)

Grizzi, Fabio, Franceschini, Barbara, Hamrick, Cody, Frezza, Eldo E, Cobos, Everardo, Chiriva-Internati, Maurizio

Abstract Despite advances in our cellular and molecular knowledge, hepatocellular carcinoma (HCC) remains one of the major public health problems throughout the world. It is now known to be highly...

Cancer initiation and progression: an unsimplifiable complexity (2006)

Grizzi, Fabio, Di Ieva, Antonio, Russo, Carlo, Frezza, Eldo E, Cobos, Everardo, Muzzio, Pier, ...

Abstract Background Cancer remains one of the most complex diseases affecting humans and, despite the impressive advances that have been made in molecular and cell biology, how cancer cells progress...

Quantitative evaluation of RASSF1Amethylation in the non-lesional, regenerative and neoplastic liver (2006)

Di Gioia, Sonia, Bianchi, Paolo, Destro, Annarita, Grizzi, Fabio, Malesci, Alberto, Laghi, Luigi, ...

Abstract Background Epigenetic changes during ageing and their relationship with cancer are under the focus of intense research. RASSF1A and NORE1A are novel genes acting in concert in the...

Cancer: looking for simplicity and finding complexity (2006)

Grizzi, Fabio, Chiriva-Internati, Maurizio

Abstract Cancer is one of the most complex dynamic human disease. Despite rapid advances in the fields of molecular and cell biology, it is still widely debated as to how neoplastic cells progress...

Sperm protein 17 is expressed in human nervous system tumours (2006)

Grizzi, Fabio, Gaetani, Paolo, Franceschini, Barbara, Di Ieva, Antonio, Colombo, Piergiuseppe, Ceva-Grimaldi, Giorgia, ...

Abstract Background Human sperm protein 17 (Sp17) is a highly conserved protein that was originally isolated from a rabbit epididymal sperm membrane and testis membrane pellet. It has recently been...

The complexity of anatomical systems (2005)

Grizzi, Fabio, Chiriva-Internati, Maurizio

Abstract Background The conception of anatomical entities as a hierarchy of infinitely graduated forms and the increase in the number of observed anatomical sub-entities and structural variables has...

Quantitative evaluation and modeling of two-dimensional neovascular network complexity: the surface fractal dimension (2005)

Grizzi, Fabio, Russo, Carlo, Colombo, Piergiuseppe, Franceschini, Barbara, Frezza, Eldo E, Cobos, Everardo, ...

Abstract Background Modeling the complex development and growth of tumor angiogenesis using mathematics and biological data is a burgeoning area of cancer research. Architectural complexity is the...

Cancer immunotherapy: avoiding the road to perdition (2004)

Chiriva-Internati, Maurizio, Grizzi, Fabio, Bright, Robert K, Martin Kast, W

Abstract The hypothesis that human cancers express antigens that can be specifically targeted by cell mediated immunity has become a scientifically justifiable rationale for the design and clinical...

Cancer immunotherapy: avoiding the road to perdition

Chiriva-Internati, Maurizio, Grizzi, Fabio, Bright, Robert K, Martin Kast, W

The hypothesis that human cancers express antigens that can be specifically targeted by cell mediated immunity has become a scientifically justifiable rationale for the design and clinical testing of...

Cancer: looking for simplicity and finding complexity

Grizzi, Fabio, Chiriva-Internati, Maurizio

Cancer is one of the most complex dynamic human disease. Despite rapid advances in the fields of molecular and cell biology, it is still widely debated as to how neoplastic cells progress through...

Ochratoxin A–Induced Renal Cortex Fibrosis and Epithelial-to-Mesenchymal Transition: Molecular Mechanisms of Ochratoxin A-Injury and Potential Effects of Red Wine

Gagliano, Nicoletta, Torri, Carlo, Donetti, Elena, Grizzi, Fabio, Costa, Francesco, Bertelli, Alberto AE, ...

We characterized the effect of chronic ochratoxin A (OTA) on rat kidney cortex, analyzing collagen content and collagen turnover and the major markers of epithelial-to-mesenchymal transition (EMT),...

Cancer immunotherapy: avoiding the road to perdition

Chiriva-Internati, Maurizio, Grizzi, Fabio, Bright, Robert K, Martin Kast, W

The hypothesis that human cancers express antigens that can be specifically targeted by cell mediated immunity has become a scientifically justifiable rationale for the design and clinical testing of...

Cancer: looking for simplicity and finding complexity

Grizzi, Fabio, Chiriva-Internati, Maurizio

Cancer is one of the most complex dynamic human disease. Despite rapid advances in the fields of molecular and cell biology, it is still widely debated as to how neoplastic cells progress through...

Ochratoxin A–Induced Renal Cortex Fibrosis and Epithelial-to-Mesenchymal Transition: Molecular Mechanisms of Ochratoxin A-Injury and Potential Effects of Red Wine

Gagliano, Nicoletta, Torri, Carlo, Donetti, Elena, Grizzi, Fabio, Costa, Francesco, Bertelli, Alberto AE, ...

We characterized the effect of chronic ochratoxin A (OTA) on rat kidney cortex, analyzing collagen content and collagen turnover and the major markers of epithelial-to-mesenchymal transition (EMT),...

Usefulness of cancer-testis antigens as biomarkers for the diagnosis and treatment of hepatocellular carcinoma

Grizzi, Fabio, Franceschini, Barbara, Hamrick, Cody, Frezza, Eldo E, Cobos, Everardo, Chiriva-Internati, Maurizio

Despite advances in our cellular and molecular knowledge, hepatocellular carcinoma (HCC) remains one of the major public health problems throughout the world. It is now known to be highly...

Vascular architecture: is it a helpful histopathological biomarker for hepatocellular carcinoma?

Grizzi, Fabio, Franceschini, Barbara, Fiamengo, Barbara, Russo, Carlo, Dioguardi, Nicola

Hepatocellular carcinoma (HCC) remains one of the major public health problems throughout the world. Although originally associated with tumorigenic processes, liver angiogenesis has also been...