Tal Pupko, Itay Mayrose, Fabian Glaser
Motivation: A number of proteins of known threedimensional (3D) structure exist, with yet unknown function. In light of the recent progress in structure determination methodology, this number is...
Fabian Glaser, Tal Pupko, Dalit Bechor, Eric Martz
Summary: Recently, we developed algorithmic tools for the identification of functionally important regions in a protein of known 3D-structure by estimating the degree of conservation of the...
Melamed, Daniel, Mark-Danieli, Michal, Kenan-Eichler, Michal, Kraus, Osnat, Castiel, Asher, Laham, Nihay, ...
The retroviral Gag precursor plays an important role in the assembly of virion particles. The capsid (CA) protein of the Gag molecule makes a major contribution to this process. In the crystal...
ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures
Landau, Meytal, Mayrose, Itay, Rosenberg, Yossi, Glaser, Fabian, Martz, Eric, Pupko, Tal, ...
Key amino acid positions that are important for maintaining the 3D structure of a protein and/or its function(s), e.g. catalytic activity, binding to ligand, DNA or other proteins, are often under...
Melchionda, Salvatore, Ahituv, Nadav, Bisceglia, Luigi, Sobe, Tama, Glaser, Fabian, Rabionet, Raquel, ...
Mutations in the unconventional myosin VI gene, Myo6, are associated with deafness and vestibular dysfunction in the Snell’s waltzer (sv) mouse. The corresponding human gene, MYO6, is located on...
Melamed, Daniel, Mark-Danieli, Michal, Kenan-Eichler, Michal, Kraus, Osnat, Castiel, Asher, Laham, Nihay, ...
The retroviral Gag precursor plays an important role in the assembly of virion particles. The capsid (CA) protein of the Gag molecule makes a major contribution to this process. In the crystal...
ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures
Landau, Meytal, Mayrose, Itay, Rosenberg, Yossi, Glaser, Fabian, Martz, Eric, Pupko, Tal, ...
Key amino acid positions that are important for maintaining the 3D structure of a protein and/or its function(s), e.g. catalytic activity, binding to ligand, DNA or other proteins, are often under...
Melchionda, Salvatore, Ahituv, Nadav, Bisceglia, Luigi, Sobe, Tama, Glaser, Fabian, Rabionet, Raquel, ...
Mutations in the unconventional myosin VI gene, Myo6, are associated with deafness and vestibular dysfunction in the Snell’s waltzer (sv) mouse. The corresponding human gene, MYO6, is located on...
Shazman, Shula, Celniker, Gershon, Haber, Omer, Glaser, Fabian, Mandel-Gutfreund, Yael
Positively charged electrostatic patches on protein surfaces are usually indicative of nucleic acid binding interfaces. Interestingly, many proteins which are not involved in nucleic acid binding...
Portnoy, Victoria, Palnizky, Gili, Yehudai-Resheff, Shlomit, Glaser, Fabian, Schuster, Gadi
PNPase is a major exoribonuclease that plays an important role in the degradation, processing, and polyadenylation of RNA in prokaryotes and organelles. This phosphorolytic processive enzyme uses...