Laurençon, Anne, Dubruille, Raphaëlle, Efimenko, Evgeni, Grenier, Guillaume, Bissett, Ryan, Cortier, Elisabeth, ...
Abstract Background Regulatory factor X (RFX) transcription factors play a key role in ciliary assembly in nematode, Drosophila and mouse. Using the tremendous advantages of comparative genomics in...
Chen, Nansheng, Mah, Allan, Blacque, Oliver E, Chu, Jeffrey, Phgora, Kiran, Bakhoum, Mathieu W, ...
Abstract Background The recent availability of genome sequences of multiple related Caenorhabditis species has made it possible to identify, using comparative genomics, similarly transcribed genes in...
Efimenko, Evgeni, Blacque, Oliver E., Ou, Guangshuo, Haycraft, Courtney J., Yoder, Bradley K., Scholey, Jonathan M., ...
The intraflagellar transport (IFT) machinery required to build functional cilia consists of a multisubunit complex whose molecular composition, organization, and function are poorly understood. Here,...
Chen, Nansheng, Mah, Allan, Blacque, Oliver E, Chu, Jeffrey, Phgora, Kiran, Bakhoum, Mathieu W, ...
Comparative genomic analysis of three nematode species identifies 93 genes that encode putative components of the ciliated neurons in C. elegans and are subject to the same regulatory control.
An Essential Role for DYF-11/MIP-T3 in Assembling Functional Intraflagellar Transport Complexes
Li, Chunmei, Inglis, Peter N., Leitch, Carmen C., Efimenko, Evgeni, Zaghloul, Norann A., Mok, Calvin A., ...
MIP-T3 is a human protein found previously to associate with microtubules and the kinesin-interacting neuronal protein DISC1 (Disrupted-in-Schizophrenia 1), but whose cellular function(s) remains...
Laurençon, Anne, Dubruille, Raphaëlle, Efimenko, Evgeni, Grenier, Guillaume, Bissett, Ryan, Cortier, Elisabeth, ...
An RFX-binding site is shown to be conserved in the promoters of a subset of ciliary genes and a subsequent screen for this site in two Drosophila species identified novel RFX target genes that are...