Everardo Cobos

Protective CD8+ T-cell responses to cytomegalovirus driven by rAAV/GFP/IE1 loading of dendritic cells (2008)

Yu, Yuefei, Pilgrim, Petra, Yan, Juqiang, Zhou, Wei, Jenkins, Marjorie, Gagliano, Nicoletta, ...

Abstract Background Recent studies demonstrate that recombinant adeno-associated virus (rAAV)-based antigen loading of dendritic cells (DCs) generates in vitro , significant and rapid cytotoxic...

The pituitary tumor transforming gene 1 (PTTG-1): An immunological target for multiple myeloma (2008)

Chiriva-Internati, Maurizio, Ferrari, Raffaele, Prabhakar, Madhavi, Yu, Yuefei, Baggoni, Luigi, Moreno, Jorge, ...

Abstract Background Multiple Myeloma is a cancer of B plasma cells, which produce non-specific antibodies and proliferate uncontrolled. Due to the potential relapse and non-specificity of current...

Usefulness of cancer-testis antigens as biomarkers for the diagnosis and treatment of hepatocellular carcinoma (2007)

Grizzi, Fabio, Franceschini, Barbara, Hamrick, Cody, Frezza, Eldo E, Cobos, Everardo, Chiriva-Internati, Maurizio

Abstract Despite advances in our cellular and molecular knowledge, hepatocellular carcinoma (HCC) remains one of the major public health problems throughout the world. It is now known to be highly...

Cancer initiation and progression: an unsimplifiable complexity (2006)

Grizzi, Fabio, Di Ieva, Antonio, Russo, Carlo, Frezza, Eldo E, Cobos, Everardo, Muzzio, Pier, ...

Abstract Background Cancer remains one of the most complex diseases affecting humans and, despite the impressive advances that have been made in molecular and cell biology, how cancer cells progress...

Quantitative evaluation and modeling of two-dimensional neovascular network complexity: the surface fractal dimension (2005)

Grizzi, Fabio, Russo, Carlo, Colombo, Piergiuseppe, Franceschini, Barbara, Frezza, Eldo E, Cobos, Everardo, ...

Abstract Background Modeling the complex development and growth of tumor angiogenesis using mathematics and biological data is a burgeoning area of cancer research. Architectural complexity is the...

FAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cells (2005)

Nalbant, Demet, Youn, Hyewon, Nalbant, S Isil, Sharma, Savitha, Cobos, Everardo, Beale, Elmus G, ...

Abstract Background Hematopoiesis is a complex developmental process controlled by a large number of factors that regulate stem cell renewal, lineage commitment and differentiation. Secreted...

Usefulness of cancer-testis antigens as biomarkers for the diagnosis and treatment of hepatocellular carcinoma

Grizzi, Fabio, Franceschini, Barbara, Hamrick, Cody, Frezza, Eldo E, Cobos, Everardo, Chiriva-Internati, Maurizio

Despite advances in our cellular and molecular knowledge, hepatocellular carcinoma (HCC) remains one of the major public health problems throughout the world. It is now known to be highly...

Abi1 gene silencing by short hairpin RNA impairs Bcr-Abl-induced cell adhesion and migration in vitro and leukemogenesis in vivo

Yu, Weidong, Sun, Xiaolin, Clough, Nancy, Cobos, Everardo, Tao, Yunxia, Dai, Zonghan

Abl interactor (Abi) 1 was first identified as the downstream target of Abl tyrosine kinases and was found to be dysregulated in leukemic cells expressing oncogenic Bcr-Abl and v-Abl. Although the...