Evelina Gatti

Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice (1999)

Lu, Hong-Tao, Yang, Derek D., Wysk, Mark Allen, Gatti, Evelina, Mellman, Ira, Davis, Roger J., ...

The p38 mitogen-activated protein kinase (MAPK) pathway, like the c-Jun N-terminal kinase (JNK) MAPK pathway, is activated in response to cellular stress and inflammation and is involved in many...

Human cathepsin S, but not cathepsin L, degrades efficiently MHC class II-associated invariant chain in nonprofessional APCs

Bania, Jacek, Gatti, Evelina, Lelouard, Hugues, David, Alexandre, Cappello, Fanny, Weber, Ekkehard, ...

MHC class II-restricted antigen presentation plays a central role in the immune response against exogenous antigens. The association of invariant (Ii) chain with MHC class II dimers is required for...

Human cathepsin S, but not cathepsin L, degrades efficiently MHC class II-associated invariant chain in nonprofessional APCs

Bania, Jacek, Gatti, Evelina, Lelouard, Hugues, David, Alexandre, Cappello, Fanny, Weber, Ekkehard, ...

MHC class II-restricted antigen presentation plays a central role in the immune response against exogenous antigens. The association of invariant (Ii) chain with MHC class II dimers is required for...

Dendritic cell aggresome-like induced structures are dedicated areas for ubiquitination and storage of newly synthesized defective proteins

Lelouard, Hugues, Ferrand, Vincent, Marguet, Didier, Bania, Jacek, Camosseto, Voahirana, David, Alexandre, ...

In response to inflammatory stimulation, dendritic cells (DCs) have a remarkable pattern of differentiation (maturation) that exhibits specific mechanisms to control antigen processing and...

Invariant Chain Controls H2-M Proteolysis in Mouse Splenocytes and Dendritic Cells

Pierre, Philippe, Shachar, Idit, Matza, Didi, Gatti, Evelina, Flavell, Richard A., Mellman, Ira

The association of invariant (Ii) chain with major histocompatibility complex (MHC) class II dimers is required for proper antigen presentation to T cells by antigen-presenting cells. Mice lacking Ii...

MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation

De Gassart, Aude, Camosseto, Voahirana, Thibodeau, Jacques, Ceppi, Maurizio, Catalan, Nadia, Pierre, Philippe, ...

In response to Toll-like receptor ligands, dendritic cells (DCs) dramatically enhance their antigen presentation capacity by stabilizing at the cell-surface MHC II molecules. We demonstrate here...