Eric S. Daar

Human immunodeficiency virus type 1 clade B superinfection: Evidence for differential immune containment of distinct clade B strains (2005)

Yang, Otto O, Daar, Eric S, Jamieson, Beth D, Balamurugan, Arumugam, Smith, Davey M, Pitt, Jacqueline A, ...

Sequential infection with different strains of human immunodeficiency virus type 1 (HIV-1) is a rarely identified phenomenon with important implications for immunopathogenesis and vaccine...

Human Immunodeficiency Virus Inhibits Multilineage Hematopoiesis In Vivo

Koka, Prasad S., Fraser, John K., Bryson, Yvonne, Bristol, Gregory C., Aldrovandi, Grace M., Daar, Eric S., ...

Human immunodeficiency virus type 1 (HIV-1)-infected individuals often exhibit multiple hematopoietic abnormalities reaching far beyond loss of CD4+ lymphocytes. We used the SCID-hu (Thy/Liv) mouse...

Reduced Susceptibility of Human Immunodeficiency Virus Type 1 (HIV-1) from Patients with Primary HIV Infection to Nonnucleoside Reverse Transcriptase Inhibitors Is Associated with Variation at Novel Amino Acid Sites

Brown, Andrew J. Leigh, Precious, Heather M., Whitcomb, Jeannette M., Wong, Joseph K., Quigg, Marlynne, Huang, Wei, ...

Recently, significant numbers of individuals with primary human immunodeficiency virus (HIV) infection have been found to harbor viral strains with reduced susceptibility to antiretroviral drugs. In...

Antibody from Patients with Acute Human Immunodeficiency Virus (HIV) Infection Inhibits Primary Strains of HIV Type 1 in the Presence of Natural-Killer Effector Cells

Forthal, Donald N., Landucci, Gary, Daar, Eric S.

The partial control of viremia during acute human immunodeficiency virus type 1 (HIV-1) infection is accompanied by an HIV-1-specific cytotoxic T-lymphocyte (CTL) response and an absent or infrequent...

Genetic Basis of Hypersusceptibility to Protease Inhibitors and Low Replicative Capacity of Human Immunodeficiency Virus Type 1 Strains in Primary Infection

Leigh Brown, Andrew J., Frost, Simon D. W., Good, Benjamin, Daar, Eric S., Simon, Viviana, Markowitz, Martin, ...

The initial virus strains from as many as 12% of individuals with primary human immunodeficiency virus (HIV) infection have a 50% inhibitory concentration ≤0.4-fold that of HIV type 1NL4-3...

Human Immunodeficiency Virus Type 1 (HIV-1) Diversity at Time of Infection Is Not Restricted to Certain Risk Groups or Specific HIV-1 Subtypes

Sagar, Manish, Kirkegaard, Erin, Long, E. Michelle, Celum, Connie, Buchbinder, Susan, Daar, Eric S., ...

African women frequently acquire several genetically distinct human immunodeficiency virus type 1 (HIV-1) variants from a heterosexual partner, whereas the acquisition of multiple variants appears to...

Human Immunodeficiency Virus Type 1 Clade B Superinfection: Evidence for Differential Immune Containment of Distinct Clade B Strains

Yang, Otto O., Daar, Eric S., Jamieson, Beth D., Balamurugan, Arumugam, Smith, Davey M., Pitt, Jacqueline A., ...

Sequential infection with different strains of human immunodeficiency virus type 1 (HIV-1) is a rarely identified phenomenon with important implications for immunopathogenesis and vaccine...

HLA-B63 Presents HLA-B57/B58-Restricted Cytotoxic T-Lymphocyte Epitopes and Is Associated with Low Human Immunodeficiency Virus Load

Frahm, Nicole, Adams, Sharon, Kiepiela, Photini, Linde, Caitlyn H., Hewitt, Hannah S., Lichterfeld, Mathias, ...

Several HLA class I alleles have been associated with slow human immunodeficiency virus (HIV) disease progression, supporting the important role HLA class I-restricted cytotoxic T lymphocytes (CTL)...

Human Immunodeficiency Virus Inhibits Multilineage Hematopoiesis In Vivo

Koka, Prasad S., Fraser, John K., Bryson, Yvonne, Bristol, Gregory C., Aldrovandi, Grace M., Daar, Eric S., ...

Human immunodeficiency virus type 1 (HIV-1)-infected individuals often exhibit multiple hematopoietic abnormalities reaching far beyond loss of CD4+ lymphocytes. We used the SCID-hu (Thy/Liv) mouse...

Reduced Susceptibility of Human Immunodeficiency Virus Type 1 (HIV-1) from Patients with Primary HIV Infection to Nonnucleoside Reverse Transcriptase Inhibitors Is Associated with Variation at Novel Amino Acid Sites

Brown, Andrew J. Leigh, Precious, Heather M., Whitcomb, Jeannette M., Wong, Joseph K., Quigg, Marlynne, Huang, Wei, ...

Recently, significant numbers of individuals with primary human immunodeficiency virus (HIV) infection have been found to harbor viral strains with reduced susceptibility to antiretroviral drugs. In...

Antibody from Patients with Acute Human Immunodeficiency Virus (HIV) Infection Inhibits Primary Strains of HIV Type 1 in the Presence of Natural-Killer Effector Cells

Forthal, Donald N., Landucci, Gary, Daar, Eric S.

The partial control of viremia during acute human immunodeficiency virus type 1 (HIV-1) infection is accompanied by an HIV-1-specific cytotoxic T-lymphocyte (CTL) response and an absent or infrequent...

Genetic Basis of Hypersusceptibility to Protease Inhibitors and Low Replicative Capacity of Human Immunodeficiency Virus Type 1 Strains in Primary Infection

Leigh Brown, Andrew J., Frost, Simon D. W., Good, Benjamin, Daar, Eric S., Simon, Viviana, Markowitz, Martin, ...

The initial virus strains from as many as 12% of individuals with primary human immunodeficiency virus (HIV) infection have a 50% inhibitory concentration ≤0.4-fold that of HIV type 1NL4-3...

Human Immunodeficiency Virus Type 1 (HIV-1) Diversity at Time of Infection Is Not Restricted to Certain Risk Groups or Specific HIV-1 Subtypes

Sagar, Manish, Kirkegaard, Erin, Long, E. Michelle, Celum, Connie, Buchbinder, Susan, Daar, Eric S., ...

African women frequently acquire several genetically distinct human immunodeficiency virus type 1 (HIV-1) variants from a heterosexual partner, whereas the acquisition of multiple variants appears to...

Human Immunodeficiency Virus Type 1 Clade B Superinfection: Evidence for Differential Immune Containment of Distinct Clade B Strains

Yang, Otto O., Daar, Eric S., Jamieson, Beth D., Balamurugan, Arumugam, Smith, Davey M., Pitt, Jacqueline A., ...

Sequential infection with different strains of human immunodeficiency virus type 1 (HIV-1) is a rarely identified phenomenon with important implications for immunopathogenesis and vaccine...

HLA-B63 Presents HLA-B57/B58-Restricted Cytotoxic T-Lymphocyte Epitopes and Is Associated with Low Human Immunodeficiency Virus Load

Frahm, Nicole, Adams, Sharon, Kiepiela, Photini, Linde, Caitlyn H., Hewitt, Hannah S., Lichterfeld, Mathias, ...

Several HLA class I alleles have been associated with slow human immunodeficiency virus (HIV) disease progression, supporting the important role HLA class I-restricted cytotoxic T lymphocytes (CTL)...

A Small-molecule Inhibitor Directed against the Chemokine Receptor CXCR4 Prevents its Use as an HIV-1 Coreceptor

Doranz, Benjamin J., Grovit-Ferbas, Kathie, Sharron, Matthew P., Mao, Si-Hua, Goetz, Matthew Bidwell, Daar, Eric S., ...

The chemokine receptor CXCR4 is the major coreceptor used for cellular entry by T cell– tropic human immunodeficiency virus (HIV)-1 strains, whereas CCR5 is used by macrophage (M)-tropic strains....

Primary Human Immunodeficiency Virus Type 1 (HIV-1) Infection during HIV-1 Gag Vaccination▿

Balamurugan, Arumugam, Lewis, Martha J., Kitchen, Christina M. R., Robertson, Michael N., Shiver, John W., Daar, Eric S., ...

Vaccination for human immunodeficiency virus type 1 (HIV-1) remains an elusive goal. Whether an unsuccessful vaccine might not only fail to provoke detectable immune responses but also could actually...