Lemay, Julie, Maidou-Peindara, Priscilla, Bader, Thomas, Ennifar, Eric, Rain, Jean-Christophe, Benarous, Richard, ...
Abstract Reverse transcription of the genetic material of human immunodeficiency virus type 1 (HIV-1) is a critical step in the replication cycle of this virus. This process, catalyzed by reverse...
A crystallographic study of the binding of 13 metal ions to two related RNA duplexes
Ennifar, Eric, Walter, Philippe, Dumas, Philippe
Metal ions, and magnesium in particular, are known to be involved in RNA folding by stabilizing secondary and tertiary structures, and, as cofactors, in RNA enzymatic activity. We have conducted a...
Ennifar, Eric, Meyer, Joachim E. W., Buchholz, Frank, Stewart, A. Francis, Suck, Dietrich
Escherichia coli phage P1 Cre recombinase catalyzes the site-specific recombination of DNA containing loxP sites. We report here two crystal structures of a wild-type Cre recombinase–loxP synaptic...
Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell
Ennifar, Eric, Paillart, Jean-Christophe, Bodlenner, Anne, Walter, Philippe, Weibel, Jean-Marc, Aubertin, Anne-Marie, ...
The kissing-loop complex that initiates dimerization of genomic RNA is crucial for Human Immunodeficiency Virus Type 1 (HIV-1) replication. We showed that owing to its strong similitude with the...
A crystallographic study of the binding of 13 metal ions to two related RNA duplexes
Ennifar, Eric, Walter, Philippe, Dumas, Philippe
Metal ions, and magnesium in particular, are known to be involved in RNA folding by stabilizing secondary and tertiary structures, and, as cofactors, in RNA enzymatic activity. We have conducted a...
Ennifar, Eric, Meyer, Joachim E. W., Buchholz, Frank, Stewart, A. Francis, Suck, Dietrich
Escherichia coli phage P1 Cre recombinase catalyzes the site-specific recombination of DNA containing loxP sites. We report here two crystal structures of a wild-type Cre recombinase–loxP synaptic...
Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell
Ennifar, Eric, Paillart, Jean-Christophe, Bodlenner, Anne, Walter, Philippe, Weibel, Jean-Marc, Aubertin, Anne-Marie, ...
The kissing-loop complex that initiates dimerization of genomic RNA is crucial for Human Immunodeficiency Virus Type 1 (HIV-1) replication. We showed that owing to its strong similitude with the...
Ennifar, Eric, Basquin, Jerôme, Birkenbihl, Rainer, Suck, Dietrich
The Holliday junction resolvase of the archaeal virus SIRV2 infecting the archaeon Sulfolobus islandicus has been crystallized and a full data set has been collected at 3.4 Å resolution. Analysis...
Bernacchi, Serena, Freisz, Séverine, Maechling, Clarisse, Spiess, Bernard, Marquet, Roland, Dumas, Philippe, ...
Owing to a striking, and most likely fortuitous, structural and sequence similarity with the bacterial 16 S ribosomal A site, the RNA kissing-loop complex formed by the HIV-1 genomic RNA dimerization...
Influence of C-5 halogenation of uridines on hairpin versus duplex RNA folding
Ennifar, Eric, Bernacchi, Serena, Wolff, Philippe, Dumas, Philippe
Halogenation of bases is a widespread method used for solving crystal structures of nucleic acids. However, this modification may have important consequences on RNA folding and thus on the success of...
Lemay, Julie, Maidou-Peindara, Priscilla, Bader, Thomas, Ennifar, Eric, Rain, Jean-Christophe, Benarous, Richard, ...
Reverse transcription of the genetic material of human immunodeficiency virus type 1 (HIV-1) is a critical step in the replication cycle of this virus. This process, catalyzed by reverse...