Eoghan D. Harrington

Large gene overlaps in prokaryotic genomes: result of functional constraints or mispredictions? (2008)

Pallejà, Albert, Harrington, Eoghan D, Bork, Peer

Abstract Background Across the fully sequenced microbial genomes there are thousands of examples of overlapping genes. Many of these are only a few nucleotides long and are thought to function by...

Protein coding potential of retroviruses and other transposable elements in vertebrate genomes

Zdobnov, Evgeny M., Campillos, Mónica, Harrington, Eoghan D., Torrents, David, Bork, Peer

We suggest an annotation strategy for genes encoded by retroviruses and transposable elements (RETRA genes) based on a set of marker protein domains. Usually RETRA genes are masked in vertebrate...

Complex genomic rearrangements lead to novel primate gene function

Ciccarelli, Francesca D., Von Mering, Christian, Suyama, Mikita, Harrington, Eoghan D., Izaurralde, Elisa, Bork, Peer

Orthologous genes that maintain a single-copy status in a broad range of species may indicate a selection against gene duplication. If this is the case, then duplicates of such genes that do survive...

Protein coding potential of retroviruses and other transposable elements in vertebrate genomes

Zdobnov, Evgeny M., Campillos, Mónica, Harrington, Eoghan D., Torrents, David, Bork, Peer

We suggest an annotation strategy for genes encoded by retroviruses and transposable elements (RETRA genes) based on a set of marker protein domains. Usually RETRA genes are masked in vertebrate...

Complex genomic rearrangements lead to novel primate gene function

Ciccarelli, Francesca D., Von Mering, Christian, Suyama, Mikita, Harrington, Eoghan D., Izaurralde, Elisa, Bork, Peer

Orthologous genes that maintain a single-copy status in a broad range of species may indicate a selection against gene duplication. If this is the case, then duplicates of such genes that do survive...