Emmanuel Favry

The transcriptional activity of RNA polymerase I is a key determinant for the level of all ribosome components

Laferté, Arnaud, Favry, Emmanuel, Sentenac, André, Riva, Michel, Carles, Christophe, Chédin, Stéphane

Regulation of ribosome biogenesis is a key element of cell biology, not only because ribosomes are directly required for growth, but also because ribosome production monopolizes nearly 80% of the...

Selectivity and proofreading both contribute significantly to the fidelity of RNA polymerase III transcription

Alic, Nazif, Ayoub, Nayla, Landrieux, Emilie, Favry, Emmanuel, Baudouin-Cornu, Peggy, Riva, Michel, ...

We examine here the mechanisms ensuring the fidelity of RNA synthesis by RNA polymerase III (Pol III). Misincorporation could only be observed by using variants of Pol III deficient in the intrinsic...