Elma Z. Tchilian

A high-frequency polymorphism in exon 6 of the CD45 tyrosine phosphatase gene (PTPRC) resulting in altered isoform expression

Stanton, Tara, Boxall, Sally, Hirai, Kouzo, Dawes, Ritu, Tonks, Susan, Yasui, Tomoyo, ...

CD45 (leukocyte common) antigen is a hemopoietic cell-specific tyrosine phosphatase essential for antigen receptor-mediated signaling in lymphocytes. The molecule undergoes complex alternative...

A high-frequency polymorphism in exon 6 of the CD45 tyrosine phosphatase gene (PTPRC) resulting in altered isoform expression

Stanton, Tara, Boxall, Sally, Hirai, Kouzo, Dawes, Ritu, Tonks, Susan, Yasui, Tomoyo, ...

CD45 (leukocyte common) antigen is a hemopoietic cell-specific tyrosine phosphatase essential for antigen receptor-mediated signaling in lymphocytes. The molecule undergoes complex alternative...

CD45 negatively regulates tumour necrosis factor and interleukin-6 production in dendritic cells

Piercy, Jenny, Petrova, Svetla, Tchilian, Elma Z, Beverley, Peter C L

CD45 is known to regulate signalling through many different surface receptors in diverse haemopoietic cell types. Here we report for the first time that CD45−/− bone marrow dendritic cells (BMDC)...