Elliot M. Meyerowitz

Genome-Wide Analysis of Gene Expression during Early Arabidopsis Flower Development (2006)

Wellmer, Frank, Alves-Ferreira, Márcio, Dubois, Annick, Riechmann, José Luis, Meyerowitz, Elliot M.

Detailed information about stage-specific changes in gene expression is crucial for the understanding of the gene regulatory networks underlying development. Here, we describe the global gene...

Genome-Wide Analysis of Gene Expression during Early Arabidopsis Flower Development (2006)

Frank Wellmer, Márcio Alves-Ferreira, Annick Dubois, José Luis Riechmann, Elliot M. Meyerowitz

Detailed information about stage-specific changes in gene expression is crucial for the understanding of the gene regulatory networks underlying development. Here, we describe the global gene...

Genome-Wide Analysis of Gene Expression during Early Arabidopsis Flower Development (2006)

Frank Wellmer, Marcio Alves-Ferreira, Annick Dubois, Jose Luis Riechmann, Elliot M Meyerowitz

Detailed information about stage-specific changes in gene expression is crucial for the understanding of the gene regulatory networks underlying development. Here, we describe the global gene...

ABERRANT TESTA SHAPE encodes a KANADI family member, linking polarity determination to separation and growth of Arabidopsis ovule integuments (2006)

McAbee, Jessica Messmer, Hill, Theresa A., Skinner, Debra J., Izhaki, Anat, Hauser, Bernard A., Meister, Robert J., ...

The Arabidopsis aberrant testa shape (ats) mutant produces a single integument instead of the two integuments seen in wild-type ovules. Cellular anatomy and patterns of marker gene expression...

An auxin-driven polarized transport model for phyllotaxis (2006)

Jönsson, Henrik, Heisler, Marcus G., Shapiro, Bruce E., Meyerowitz, Elliot M., Mjolsness, Eric

Recent studies show that plant organ positioning may be mediated by localized concentrations of the plant hormone auxin. Auxin patterning in the shoot apical meristem is in turn brought about by the...

Real-time lineage analysis reveals oriented cell divisions associated with morphogenesis at the shoot apex of Arabidopsis thaliana (2004)

Reddy, G. Venugopala, Heisler, Marcus G., Ehrhardt, David W., Meyerowitz, Elliot M.

Precise knowledge of spatial and temporal patterns of cell division, including number and orientation of divisions, and knowledge of cell expansion, is central to understanding morphogenesis. Our...

Floral homeotic genes are targets of gibberellin signaling in flower development (2004)

Yu, Hao, Ito, Toshiro, Zhao, Yuanxiang, Peng, Jinrong, Kumar, Prakash, Meyerowitz, Elliot M.

Gibberellins (GAS) are a class of plant hormones involved in the regulation of flower development in Arabidopsis. The GA-deficient ga1-3 mutant shows retarded growth of all floral organs, especially...

The Arabidopsis JAGGED gene encodes a zinc finger protein that promotes leaf tissue development (2004)

Ohno, Carolyn K., Reddy, G. Venugopala, Heisler, Marcus G. B., Meyerowitz, Elliot M.

Important goals in understanding leaf development are to identify genes involved in pattern specification, and also genes that translate this information into cell types and tissue structure....

Genetic and physical characterization of a region of Arabidopsis chromosome 1 containing the CLAVATA1 gene (1999)

Williams, Robert W., Meyerowitz, Elliot M., Clark, Steven E.

With the advance of Arabidopsis as a model system for understanding plant genetics, development and biochemistry, a detailed description of the genome is necessary. As such, focused projects are...

Determination of floral organ identity by Arabidopsis MADS domain homeotic proteins AP1, AP3, PI, and AG is independent of their DNA-binding specificity (1997)

Riechmann, José Luis, Meyerowitz, Elliot M.

The MADS domain homeotic proteins APETALA1 (AP1), APETALA3 (AP3), PISTILLATA (PI), and AGAMOUS (AG) combinatorially specify the identity of Arabidopsis floral organs. AP1/AP1, AG/AG, and AP3/PI...

DNA-binding properties of Arabidopsis MADS domain homeotic proteins APETALA1, APETALA3, PISTILLATA and AGAMOUS (1996)

Riechmann, José Luis, Wang, Minqin, Meyerowitz, Elliot M.

The MADS domain proteins APETALA1 (AP1), APETALA3 (AP3), PISTILLATA (PI), and AGAMOUS (AG) specify the identity of Arabidopsis floral organs. AP1 and AG homocomplexes and AP3-PI heterocomplexes bind...

The Arabidopsis homeotic genes APETALA3 and PISTILLATA are sufficient to provide the B class organ identity function (1996)

Krizek, Beth Allyn, Meyerowitz, Elliot M.

The class B organ identity genes, APETALA3 and PISTILLATA, are required to specify petal and stamen identity in the Arabidopsis flower. We show here that the activities of these two genes are...

LEUNIG regulates AGAMOUS expression in Arabidopsis flowers (1995)

Liu, Zhongchi, Meyerowitz, Elliot M.

LEUNIG was identified in a genetic screen designed to isolate second-site enhancer mutations of the floral homeotic mutant apetala2-1. leunig mutations not only enhance apetala2, but by themselves...

LEUNIG regulates AGAMOUS expression in Arabidopsis flowers (1995)

Liu, Zhongchi, Meyerowitz, Elliot M.

LEUNIG was identified in a genetic screen designed to isolate second-site enhancer mutations of the floral homeotic mutant apetala2-1. leunig mutations not only enhance apetala2, but by themselves...

Mutations in human dynamin block an intermediate stage in coated vesicle formation (1993)

Van Der Bliek, Alexander M., Redelmeier, Thomas E., Damke, Hanna, Tisdale, Ellen J., Meyerowitz, Elliot M., Schmid, Sandra L.

The role of human dynamin in receptor-mediated endocytosis was investigated by transient expression of GTP-binding domain mutants in mammalian cells. Using assays which detect intermediates in coated...

cis-acting sequences required for expression of the divergently transcribed Drosophila melanogaster Sgs-7 and Sgs-8 glue protein genes (1991)

Hofmann, Annemarie, Garfinkel, Mark D., Meyerowitz, Elliot M.

The Sgs-7 and Sgs-8 glue genes at 68C are divergently transcribed and are separated by 475 bp. Fusion genes with Adh or lacZ coding sequences were constructed, and the expression of these genes, with...

Restriction Fragment Length Polymorphism Linkage Map for Arabidopsis thaliana (1988)

Chang, Caren, Bowman, John L., DeJohn, Arthur W., Lander, Eric S., Meyerowitz, Elliot M.

We have constructed a restriction fragment length polymorphism linkage map for the nuclear genome of the flowering plant Arabidopsis thaliana. The map, containing 90 randomly distributed molecular...

Structure and expression of three light-harvesting chlorophyll a/b-binding protein genes in Arabidopsis thaliana (1986)

Leutwiler, Leslie S., Meyerowitz, Elliot M., Tobin, Elaine M.

The genome of Arabidopsis thaliana is exceedingly small, in part because it lacks the large middle repetitive DNA component characteristic of other plants. In this paper we have characterized a...

The structural genes for three Drosophila glue proteins reside at a single polytene chromosome puff locus (1983)

Crowley, Thomas E., Bond, Martha W., Meyerowitz, Elliot M.

The polytene chromosome puff at 68C on the Drosophila melanogaster third chromosome is thought from genetic experiments to contain the structural gene for one of the secreted salivary gland glue...

Cloning of the Arabidopsis WIGGUM gene identifies a role for farnesylation in meristem development

Ziegelhoffer, Eva C., Medrano, Leonard J., Meyerowitz, Elliot M.

Control of cellular proliferation in plant meristems is important for maintaining the correct number and position of developing organs. One of the genes identified in the control of floral and apical...

Specific and heritable genetic interference by double-stranded RNA in Arabidopsis thaliana

Chuang, Chiou-Fen, Meyerowitz, Elliot M.

We investigated the potential of double-stranded RNA interference (RNAi) with gene activity in Arabidopsis thaliana. To construct transformation vectors that produce RNAs capable of duplex formation,...

ETR2 is an ETR1-like gene involved in ethylene signaling in Arabidopsis

Sakai, Hajime, Hua, Jian, Chen, Qianhong G., Chang, Caren, Medrano, Leonard J., Bleecker, Anthony B., ...

The plant hormone ethylene regulates a variety of processes of growth and development. To identify components in the ethylene signal transduction pathway, we screened for ethylene-insensitive mutants...

A dynamin GTPase mutation causes a rapid and reversible temperature-inducible locomotion defect in C. elegans

Clark, Scott G., Shurland, Dixie-Lee, Meyerowitz, Elliot M., Bargmann, Cornelia I., Van Der Bliek, Alexander M.

Drosophila shibire and its mammalian homologue dynamin regulate an early step in endocytosis. We identified a Caenorhabditis elegans dynamin gene, dyn-1, based upon hybridization to the Drosophila...

A possible role for kinase-associated protein phosphatase in the Arabidopsis CLAVATA1 signaling pathway

Williams, Robert W., Wilson, Jeanne M., Meyerowitz, Elliot M.

Continuous growth and development in plants are accomplished by meristems, groups of undifferentiated cells that persist as stem cells and initiate organs. While the structures of the apical and...

Non-AUG Initiation of AGAMOUS mRNA Translation in Arabidopsis thaliana

Riechmann, José Luis, Ito, Toshiro, Meyerowitz, Elliot M.

The MADS box organ identity gene AGAMOUS (AG) controls several steps during Arabidopsis thaliana flower development. AG cDNA contains an open reading frame that lacks an ATG triplet to function as...

Overexpression of a Gene Encoding a Cytochrome P450, CYP78A9, Induces Large and Seedless Fruit in Arabidopsis

Ito, Toshiro, Meyerowitz, Elliot M.

An activation tagging screen in which the cauliflower mosaic virus 35S enhancer was inserted randomly into an Arabidopsis genome homozygous for the floral homeotic mutation apetala2-1 (ap2-1)...

Regulation of SUP Expression Identifies Multiple Regulators Involved in Arabidopsis Floral Meristem Development

Sakai, Hajime, Krizek, Beth A., Jacobsen, Steven E., Meyerowitz, Elliot M.

During the course of flower development, floral homeotic genes are expressed in defined concentric regions of floral meristems called whorls. The SUPERMAN (SUP, also called FLO10) gene, which encodes...

The PERIANTHIA gene encodes a bZIP protein involved in the determination of floral organ number in Arabidopsis thaliana

Chuang, Chiou-Fen, Running, Mark P., Williams, Robert W., Meyerowitz, Elliot M.

Mutations in the PERIANTHIA (PAN) gene of Arabidopsis thaliana specifically transform flowers from tetramerous to largely pentamerous, which is a characteristic of flowers of ancestral plants. We...

Floral homeotic genes are targets of gibberellin signaling in flower development

Yu, Hao, Ito, Toshiro, Zhao, Yuanxiang, Peng, Jinrong, Kumar, Prakash, Meyerowitz, Elliot M.

Gibberellins (GAs) are a class of plant hormones involved in the regulation of flower development in Arabidopsis. The GA-deficient ga1-3 mutant shows retarded growth of all floral organs, especially...

Genome-Wide Analysis of Spatial Gene Expression in Arabidopsis FlowersW⃞

Wellmer, Frank, Riechmann, José Luis, Alves-Ferreira, Márcio, Meyerowitz, Elliot M.

We have compared the gene expression profiles of inflorescences of the floral homeotic mutants apetala1, apetala2, apetala3, pistillata, and agamous with that of wild-type plants using a...

HANABA TARANU Is a GATA Transcription Factor That Regulates Shoot Apical Meristem and Flower Development in ArabidopsisW⃞

Zhao, Yuanxiang, Medrano, Leonard, Ohashi, Kazuaki, Fletcher, Jennifer C., Yu, Hao, Sakai, Hajime, ...

We have isolated a new mutant, hanaba taranu (han), which affects both flower and shoot apical meristem (SAM) development in Arabidopsis thaliana. Mutants have fused sepals and reduced organ numbers...

Genome-Wide Analysis of Gene Expression during Early Arabidopsis Flower Development

Wellmer, Frank, Alves-Ferreira, Márcio, Dubois, Annick, Riechmann, José Luis, Meyerowitz, Elliot M

Detailed information about stage-specific changes in gene expression is crucial for the understanding of the gene regulatory networks underlying development. Here, we describe the global gene...

An auxin-driven polarized transport model for phyllotaxis

Jönsson, Henrik, Heisler, Marcus G., Shapiro, Bruce E., Meyerowitz, Elliot M., Mjolsness, Eric

Recent studies show that plant organ positioning may be mediated by localized concentrations of the plant hormone auxin. Auxin patterning in the shoot apical meristem is in turn brought about by the...

Lethal Mutations Flanking the 68c Glue Gene Cluster on Chromosome 3 of DROSOPHILA MELANOGASTER

Crosby, Madeline A., Meyerowitz, Elliot M.

We have conducted a genetic analysis of the region flanking the 68C glue gene cluster in Drosophila melanogaster by isolating lethal and semilethal mutations uncovered by deficiencies which span this...

Cloning of the Arabidopsis WIGGUM gene identifies a role for farnesylation in meristem development

Ziegelhoffer, Eva C., Medrano, Leonard J., Meyerowitz, Elliot M.

Control of cellular proliferation in plant meristems is important for maintaining the correct number and position of developing organs. One of the genes identified in the control of floral and apical...

Specific and heritable genetic interference by double-stranded RNA in Arabidopsis thaliana

Chuang, Chiou-Fen, Meyerowitz, Elliot M.

We investigated the potential of double-stranded RNA interference (RNAi) with gene activity in Arabidopsis thaliana. To construct transformation vectors that produce RNAs capable of duplex formation,...

ETR2 is an ETR1-like gene involved in ethylene signaling in Arabidopsis

Sakai, Hajime, Hua, Jian, Chen, Qianhong G., Chang, Caren, Medrano, Leonard J., Bleecker, Anthony B., ...

The plant hormone ethylene regulates a variety of processes of growth and development. To identify components in the ethylene signal transduction pathway, we screened for ethylene-insensitive mutants...

A dynamin GTPase mutation causes a rapid and reversible temperature-inducible locomotion defect in C. elegans

Clark, Scott G., Shurland, Dixie-Lee, Meyerowitz, Elliot M., Bargmann, Cornelia I., Van Der Bliek, Alexander M.

Drosophila shibire and its mammalian homologue dynamin regulate an early step in endocytosis. We identified a Caenorhabditis elegans dynamin gene, dyn-1, based upon hybridization to the Drosophila...

A possible role for kinase-associated protein phosphatase in the Arabidopsis CLAVATA1 signaling pathway

Williams, Robert W., Wilson, Jeanne M., Meyerowitz, Elliot M.

Continuous growth and development in plants are accomplished by meristems, groups of undifferentiated cells that persist as stem cells and initiate organs. While the structures of the apical and...

Non-AUG Initiation of AGAMOUS mRNA Translation in Arabidopsis thaliana

Riechmann, José Luis, Ito, Toshiro, Meyerowitz, Elliot M.

The MADS box organ identity gene AGAMOUS (AG) controls several steps during Arabidopsis thaliana flower development. AG cDNA contains an open reading frame that lacks an ATG triplet to function as...

Overexpression of a Gene Encoding a Cytochrome P450, CYP78A9, Induces Large and Seedless Fruit in Arabidopsis

Ito, Toshiro, Meyerowitz, Elliot M.

An activation tagging screen in which the cauliflower mosaic virus 35S enhancer was inserted randomly into an Arabidopsis genome homozygous for the floral homeotic mutation apetala2-1 (ap2-1)...

Regulation of SUP Expression Identifies Multiple Regulators Involved in Arabidopsis Floral Meristem Development

Sakai, Hajime, Krizek, Beth A., Jacobsen, Steven E., Meyerowitz, Elliot M.

During the course of flower development, floral homeotic genes are expressed in defined concentric regions of floral meristems called whorls. The SUPERMAN (SUP, also called FLO10) gene, which encodes...

The PERIANTHIA gene encodes a bZIP protein involved in the determination of floral organ number in Arabidopsis thaliana

Chuang, Chiou-Fen, Running, Mark P., Williams, Robert W., Meyerowitz, Elliot M.

Mutations in the PERIANTHIA (PAN) gene of Arabidopsis thaliana specifically transform flowers from tetramerous to largely pentamerous, which is a characteristic of flowers of ancestral plants. We...

Floral homeotic genes are targets of gibberellin signaling in flower development

Yu, Hao, Ito, Toshiro, Zhao, Yuanxiang, Peng, Jinrong, Kumar, Prakash, Meyerowitz, Elliot M.

Gibberellins (GAs) are a class of plant hormones involved in the regulation of flower development in Arabidopsis. The GA-deficient ga1-3 mutant shows retarded growth of all floral organs, especially...

Genome-Wide Analysis of Spatial Gene Expression in Arabidopsis FlowersW⃞

Wellmer, Frank, Riechmann, José Luis, Alves-Ferreira, Márcio, Meyerowitz, Elliot M.

We have compared the gene expression profiles of inflorescences of the floral homeotic mutants apetala1, apetala2, apetala3, pistillata, and agamous with that of wild-type plants using a...

HANABA TARANU Is a GATA Transcription Factor That Regulates Shoot Apical Meristem and Flower Development in ArabidopsisW⃞

Zhao, Yuanxiang, Medrano, Leonard, Ohashi, Kazuaki, Fletcher, Jennifer C., Yu, Hao, Sakai, Hajime, ...

We have isolated a new mutant, hanaba taranu (han), which affects both flower and shoot apical meristem (SAM) development in Arabidopsis thaliana. Mutants have fused sepals and reduced organ numbers...

Lethal Mutations Flanking the 68c Glue Gene Cluster on Chromosome 3 of DROSOPHILA MELANOGASTER

Crosby, Madeline A., Meyerowitz, Elliot M.

We have conducted a genetic analysis of the region flanking the 68C glue gene cluster in Drosophila melanogaster by isolating lethal and semilethal mutations uncovered by deficiencies which span this...

An auxin-driven polarized transport model for phyllotaxis

Jönsson, Henrik, Heisler, Marcus G., Shapiro, Bruce E., Meyerowitz, Elliot M., Mjolsness, Eric

Recent studies show that plant organ positioning may be mediated by localized concentrations of the plant hormone auxin. Auxin patterning in the shoot apical meristem is in turn brought about by the...

Genome-Wide Analysis of Gene Expression during Early Arabidopsis Flower Development

Wellmer, Frank, Alves-Ferreira, Márcio, Dubois, Annick, Riechmann, José Luis, Meyerowitz, Elliot M

Detailed information about stage-specific changes in gene expression is crucial for the understanding of the gene regulatory networks underlying development. Here, we describe the global gene...

Global Expression Profiling Applied to the Analysis of Arabidopsis Stamen Development1[W][OA]

Alves-Ferreira, Márcio, Wellmer, Frank, Banhara, Aline, Kumar, Vijaya, Riechmann, José Luis, Meyerowitz, Elliot M.

To obtain detailed information about gene expression during stamen development in Arabidopsis (Arabidopsis thaliana), we compared, by microarray analysis, the gene expression profile of wild-type...

The Homeotic Protein AGAMOUS Controls Late Stamen Development by Regulating a Jasmonate Biosynthetic Gene in Arabidopsis[W]

Ito, Toshiro, Ng, Kian-Hong, Lim, Tze-Soo, Yu, Hao, Meyerowitz, Elliot M.

The Arabidopsis thaliana floral homeotic gene AGAMOUS (AG) plays a central role in reproductive organ (stamen and carpel) development. AG RNA is expressed in the center of floral primordia from a...