Elizabeth Pradel

A Model of Bacterial Intestinal Infections in Drosophila melanogaster (2007)

Nadine T. Nehme, Samuel Liégeois, Beatrix Kele, Philippe Giammarinaro, Elizabeth Pradel, Jules A. Hoffmann, ...

Serratia marcescens is an entomopathogenic bacterium that opportunistically infects a wide range of hosts, including humans. In a model of septic injury, if directly introduced into the body cavity...

Bordetella pertussis TonB, a Bvg-Independent Virulence Determinant

Pradel, Elizabeth, Guiso, Nicole, Menozzi, Franco D., Locht, Camille

In gram-negative bacteria, high-affinity iron uptake requires the TonB/ExbB/ExbD envelope complex to release iron chelates from their specific outer membrane receptors into the periplasm. Based on...

Expression of the Putative Siderophore Receptor Gene bfrZ Is Controlled by the Extracytoplasmic-Function Sigma Factor BupI in Bordetella bronchiseptica

Pradel, Elizabeth, Locht, Camille

A new gene from Bordetella bronchiseptica, bfrZ encoding a putative siderophore receptor, was identified in a Fur-repressor titration assay. A bfrZ null mutant was constructed by allelic exchange....

Identification of AlcR, an AraC-Type Regulator of Alcaligin Siderophore Synthesis in Bordetella bronchiseptica and Bordetella pertussis

Pradel, Elizabeth, Guiso, Nicole, Locht, Camille

A Fur titration assay was used to isolate DNA fragments bearing putative Fur binding sites (FBS) from a partial Bordetella bronchiseptica genomic DNA library. A recombinant plasmid bearing a 3.5-kb...

The AcrAB-TolC Efflux Pump Contributes to Multidrug Resistance in the Nosocomial Pathogen Enterobacter aerogenes

Pradel, Elizabeth, Pagès, Jean-Marie

We identified the genes encoding the AcrA-AcrB-TolC efflux pump in Enterobacter aerogenes and constructed acrAB and tolC mutants from a multidrug-resistant isolate. Both derivatives were more...

The eefABC Multidrug Efflux Pump Operon Is Repressed by H-NS in Enterobacter aerogenes

Masi, Muriel, Pagès, Jean-Marie, Villard, Claude, Pradel, Elizabeth

The Enterobacter aerogenes eefABC locus, which encodes a tripartite efflux pump, was cloned by complementation of an Escherichia coli tolC mutant. E. aerogenes ΔacrA expressing EefABC became less...

Bordetella pertussis TonB, a Bvg-Independent Virulence Determinant

Pradel, Elizabeth, Guiso, Nicole, Menozzi, Franco D., Locht, Camille

In gram-negative bacteria, high-affinity iron uptake requires the TonB/ExbB/ExbD envelope complex to release iron chelates from their specific outer membrane receptors into the periplasm. Based on...

Expression of the Putative Siderophore Receptor Gene bfrZ Is Controlled by the Extracytoplasmic-Function Sigma Factor BupI in Bordetella bronchiseptica

Pradel, Elizabeth, Locht, Camille

A new gene from Bordetella bronchiseptica, bfrZ encoding a putative siderophore receptor, was identified in a Fur-repressor titration assay. A bfrZ null mutant was constructed by allelic exchange....

Identification of AlcR, an AraC-Type Regulator of Alcaligin Siderophore Synthesis in Bordetella bronchiseptica and Bordetella pertussis

Pradel, Elizabeth, Guiso, Nicole, Locht, Camille

A Fur titration assay was used to isolate DNA fragments bearing putative Fur binding sites (FBS) from a partial Bordetella bronchiseptica genomic DNA library. A recombinant plasmid bearing a 3.5-kb...

The AcrAB-TolC Efflux Pump Contributes to Multidrug Resistance in the Nosocomial Pathogen Enterobacter aerogenes

Pradel, Elizabeth, Pagès, Jean-Marie

We identified the genes encoding the AcrA-AcrB-TolC efflux pump in Enterobacter aerogenes and constructed acrAB and tolC mutants from a multidrug-resistant isolate. Both derivatives were more...

The eefABC Multidrug Efflux Pump Operon Is Repressed by H-NS in Enterobacter aerogenes

Masi, Muriel, Pagès, Jean-Marie, Villard, Claude, Pradel, Elizabeth

The Enterobacter aerogenes eefABC locus, which encodes a tripartite efflux pump, was cloned by complementation of an Escherichia coli tolC mutant. E. aerogenes ΔacrA expressing EefABC became less...

Detection and avoidance of a natural product from the pathogenic bacterium Serratia marcescens by Caenorhabditis elegans

Pradel, Elizabeth, Zhang, Yun, Pujol, Nathalie, Matsuyama, Tohey, Bargmann, Cornelia I., Ewbank, Jonathan J.

The nematode Caenorhabditis elegans is present in soils and composts, where it can encounter a variety of microorganisms. Some bacteria in these rich environments are innocuous food sources for C....

A Model of Bacterial Intestinal Infections in Drosophila melanogaster

Nehme, Nadine T, Liégeois, Samuel, Kele, Beatrix, Giammarinaro, Philippe, Pradel, Elizabeth, Hoffmann, Jules A, ...

Serratia marcescens is an entomopathogenic bacterium that opportunistically infects a wide range of hosts, including humans. In a model of septic injury, if directly introduced into the body cavity...