Elizabeth Bikoff

The p41 isoform of invariant chain is a chaperone for cathepsin L

Lennon-Duménil, Ana-Maria, Roberts, Rebecca A., Valentijn, Karine, Driessen, Christoph, Overkleeft, Herman S., Erickson, Ann, ...

The p41 splice variant of major histocompatibility complex (MHC) class II-associated invariant chain (Ii) contains a 65 aa segment that binds to the active site of cathepsin L (CatL), a lysosomal...

The p41 isoform of invariant chain is a chaperone for cathepsin L

Lennon-Duménil, Ana-Maria, Roberts, Rebecca A., Valentijn, Karine, Driessen, Christoph, Overkleeft, Herman S., Erickson, Ann, ...

The p41 splice variant of major histocompatibility complex (MHC) class II-associated invariant chain (Ii) contains a 65 aa segment that binds to the active site of cathepsin L (CatL), a lysosomal...

Invariant Chain Controls the Activity of Extracellular Cathepsin L

Fiebiger, Edda, Maehr, René, Villadangos, José, Weber, Ekkehard, Erickson, Ann, Bikoff, Elizabeth, ...

Secretion of proteases is critical for degradation of the extracellular matrix during an inflammatory response. Cathepsin (Cat) S and L are the major elastinolytic cysteine proteases in mouse...