Edward J. Michaud

Efficient gene-driven germ-line point mutagenesis of C57BL/6J mice (2005)

Michaud, Edward J, Culiat, Cymbeline T, Klebig, Mitchell L, Barker, Paul E, Cain, KT, Carpenter, Debra J, ...

Abstract Background Analysis of an allelic series of point mutations in a gene, generated by N -ethyl- N -nitrosourea (ENU) mutagenesis, is a valuable method for discovering the full scope of its...

Gli2 and Gli3 Localize to Cilia and Require the Intraflagellar Transport Protein Polaris for Processing and Function (2005)

Courtney J. Haycraft, Boglarka Banizs, Yesim Aydin-Son, Qihong Zhang, Edward J. Michaud, Bradley K. Yoder

Intraflagellar transport (IFT) proteins are essential for cilia assembly and have recently been associated with a number of developmental processes, such as left–right axis specification and limb...

Liver-specific expression of the agoutigene in transgenic mice promotes liver carcinogenesis in the absence of obesity and diabetes (2004)

Kuklin, Alexander I, Mynatt, Randall L, Klebig, Mitchell L, Kiefer, Laura L, Wilkison, William O, Woychik, Richard P, ...

Abstract Background The agouti protein is a paracrine factor that is normally present in the skin of many species of mammals. Agouti regulates the switch between black and yellow hair pigmentation by...

Gli2 and Gli3 Localize to Cilia and Require the Intraflagellar Transport Protein Polaris for Processing and Function

Haycraft, Courtney J, Banizs, Boglarka, Aydin-Son, Yesim, Zhang, Qihong, Michaud, Edward J, Yoder, Bradley K

Intraflagellar transport (IFT) proteins are essential for cilia assembly and have recently been associated with a number of developmental processes, such as left–right axis specification and limb...

Molecular and phenotypic analysis of 25 recessive, homozygous-viable alleles at the mouse agouti locus.

Miltenberger, Rosalynn J, Wakamatsu, Kazumasa, Ito, Shosuke, Woychik, Richard P, Russell, Liane B, Michaud, Edward J

Agouti is a paracrine-acting, transient antagonist of melanocortin 1 receptors that specifies the subapical band of yellow on otherwise black hairs of the wild-type coat. To better understand both...

Gli2 and Gli3 Localize to Cilia and Require the Intraflagellar Transport Protein Polaris for Processing and Function

Haycraft, Courtney J, Banizs, Boglarka, Aydin-Son, Yesim, Zhang, Qihong, Michaud, Edward J, Yoder, Bradley K

Intraflagellar transport (IFT) proteins are essential for cilia assembly and have recently been associated with a number of developmental processes, such as left–right axis specification and limb...

Molecular and phenotypic analysis of 25 recessive, homozygous-viable alleles at the mouse agouti locus.

Miltenberger, Rosalynn J, Wakamatsu, Kazumasa, Ito, Shosuke, Woychik, Richard P, Russell, Liane B, Michaud, Edward J

Agouti is a paracrine-acting, transient antagonist of melanocortin 1 receptors that specifies the subapical band of yellow on otherwise black hairs of the wild-type coat. To better understand both...

Functional Redundancy of the B9 Proteins and Nephrocystins in Caenorhabditis elegans Ciliogenesis

Williams, Corey L., Winkelbauer, Marlene E., Schafer, Jenny C., Michaud, Edward J., Yoder, Bradley K.

Meckel-Gruber syndrome (MKS), nephronophthisis (NPHP), and Joubert syndrome (JBTS) are a group of heterogeneous cystic kidney disorders with partially overlapping loci. Many of the proteins...