Eduard C. Hurt

Pseudouridine Mapping in the Saccharomyces cerevisiae Spliceosomal U Small Nuclear RNAs (snRNAs) Reveals that Pseudouridine Synthase Pus1p Exhibits a Dual Substrate Specificity for U2 snRNA and tRNA

Massenet, Séverine, Motorin, Yuri, Lafontaine, Denis L. J., Hurt, Eduard C., Grosjean, Henri, Branlant, Christiane

Pseudouridine (Ψ) residues were localized in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (UsnRNAs) by using the chemical mapping method. In contrast to vertebrate UsnRNAs, S....

The intracellular location of two aminoacyl-tRNA synthetases depends on complex formation with Arc1p

Galani, Kyriaki, Großhans, Helge, Deinert, Karina, Hurt, Eduard C., Simos, George

In yeast, two aminoacyl-tRNA synthetases, MetRS and GluRS, are associated with Arc1p. We have studied the mechanism of this complex formation and found that the non-catalytic N-terminally appended...

The cleavable pre-sequence of an imported chloroplast protein directs attached polypeptides into yeast mitochondria

Hurt, Eduard C., Soltanifar, Nouchine, Goldschmidt-Clermont, Michel, Rochaix, Jean-David, Schatz, Gottfried

The cleavable pre-sequences of imported chloroplast and mitochondrial proteins have several features in common. This structural similarity prompted us to test whether a chloroplast pre-sequence...

Pseudouridine Mapping in the Saccharomyces cerevisiae Spliceosomal U Small Nuclear RNAs (snRNAs) Reveals that Pseudouridine Synthase Pus1p Exhibits a Dual Substrate Specificity for U2 snRNA and tRNA

Massenet, Séverine, Motorin, Yuri, Lafontaine, Denis L. J., Hurt, Eduard C., Grosjean, Henri, Branlant, Christiane

Pseudouridine (Ψ) residues were localized in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (UsnRNAs) by using the chemical mapping method. In contrast to vertebrate UsnRNAs, S....

The intracellular location of two aminoacyl-tRNA synthetases depends on complex formation with Arc1p

Galani, Kyriaki, Großhans, Helge, Deinert, Karina, Hurt, Eduard C., Simos, George

In yeast, two aminoacyl-tRNA synthetases, MetRS and GluRS, are associated with Arc1p. We have studied the mechanism of this complex formation and found that the non-catalytic N-terminally appended...

The cleavable pre-sequence of an imported chloroplast protein directs attached polypeptides into yeast mitochondria

Hurt, Eduard C., Soltanifar, Nouchine, Goldschmidt-Clermont, Michel, Rochaix, Jean-David, Schatz, Gottfried

The cleavable pre-sequences of imported chloroplast and mitochondrial proteins have several features in common. This structural similarity prompted us to test whether a chloroplast pre-sequence...

Molecular Architecture of the Yeast Nuclear Pore Complex: Localization of Nsp1p Subcomplexes

Fahrenkrog, Birthe, Hurt, Eduard C., Aebi, Ueli, Panté, Nelly

The nuclear pore complex (NPC), a supramolecular assembly of ∼100 different proteins (nucleoporins), mediates bidirectional transport of molecules between the cytoplasm and the cell nucleus....