Cis-acting expression quantitative trait loci in mice (2005)
Doss, S, Schadt, E E, Drake, T A, Lusis, Aldons J
We previously reported the analysis of genome-wide expression profiles and various diabetes-related traits in a segregating cross between inbred mouse strains C57BL/6J (B6) and DBA/2J (DBA). By...
Genetic Inheritance of Gene Expression in Human Cell Lines
Monks, S. A., Leonardson, A., Zhu, H., Cundiff, P., Pietrusiak, P., Edwards, S., ...
Combining genetic inheritance information, for both molecular profiles and complex traits, is a promising strategy not only for detecting quantitative trait loci (QTLs) for complex traits but for...
Novel integrative genomics strategies to identify genes for complex traits
Forward genetics is a common approach to dissecting complex traits like common human diseases. The ultimate aim of this approach was the identification of genes that are causal for disease or other...