Gene expression patterns within cell lines are predictive of chemosensitivity (2008)
Ring, Brian Z, Chang, Stella, Ring, L Winston, Seitz, Robert S, Ross, Douglas T
Abstract Background The NCI has undertaken a twenty-year project to characterize compound sensitivity patterns in a selected set of sixty tumor derived cell lines. Previous studies have explored the...
Predicting the sites of metastases (2005)
Ring, Brian Z, Ross, Douglas T
Abstract Transplantation of human breast cancer cells into immunodeficient mice together with gene-expression microarray studies has recently identified genes implicated in the tissue tropism of...
Gusterson, Barry A, Ross, Douglas T, Heath, Victoria J, Stein, Torsten
Abstract Recent publications have classified breast cancers on the basis of expression of cytokeratin-5 and -17 at the RNA and protein levels, and demonstrated the importance of these markers in...
MAIDS: Information Dynamics Technology Requirements Study. (2005)
Goodenough,John B., Ross,Douglas T., Eanes,R. Sterlin
The report describes software technology problems concerning the use of automatic test equipment in the Army. It contains detailed analyses of three software technology areas: software modularity,...
Investigations in Computer-Aided Design for Numerically Controlled Production. (2005)
Ross, Douglas T., Ward, John E.
This report summarizes the development of a generalized 'system of software systems' for generating specialized problem-solving systems using high-level language techniques and advanced computer...
The Showit System: An Example of the Use of the AED Approach. (2005)
Ross, John R., Ross, Douglas T.
The AED approach is a collection of programming concepts and working tools for use in creating specialized, problem-solving systems. This report is a tutorial document discussing an example of the...
VERBAL AND GRAPHICAL LANGUAGE FOR THE AED SYSTEM: A PROGRESS REPORT, (2005)
Ross,Douglas T., Feldmann,Clarence G.
For Computer-Aided Design use of time-sharing a single language which can take either verbal or graphical form is required. The paper describes how a single language processing technique, which is in...
Microarrays and molecular markers for tumor classification (2002)
Ring, Brian Z, Ross, Douglas T
Abstract Human cancers have traditionally been classified according to their tissue of origin, histological characteristics and, to some extent, molecular markers. Clinical studies have associated...
Goodenough,John B., Ross,Douglas T.
The report is part of a study aimed at determining what programming language features, compiler capabilities, support tools, and program design disciplines are needed to produce reliable, easy to...
Introduction to Software Engineering with the AED-0 Language, (1998)
The report is a tutorial exposition of the AED-0 language and of a software engineering discipline based upon its use. The AED (Automated Engineering Design) System has been developed over a ten-year...
AED-0 Programmer's Guide. (1998)
Feldmann, Clarence G., Ross, Douglas T., Rodriguez, Jorge E.
The AED (Automated Engineering Design) System has been developed over a 10-year period by the M. I. T. Computer-Aided Design Project. The report is a user reference manual for the AED-0 language and...
TMDE Task 05, Information Dynamics. MAIDS Study System Organization Technology. (1998)
Goodenough, John B., Ross, Douglas T.
System organization is an issue which relates to how one should design software systems that will be able to take advantage of differing underlying machine organizations and be adaptable to meet...
Group Technology is a philosophy of discrete batch manufacturing in which work is organized to exploit the underlying sameness between otherwise differing groups of parts. An important methodology is...
Integrated Computer-Aided Manufacturing (ICAM). (1998)
The soundness of the concept of a common framework that displays all the functions of discrete parts manufacturing is demonstrated. The detailed relaionships of those functions are also shown in the...
Vita.
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
Perou, Charles M., Jeffrey, Stefanie S., Van De Rijn, Matt, Rees, Christian A., Eisen, Michael B., Ross, Douglas T., ...
cDNA microarrays and a clustering algorithm were used to identify patterns of gene expression in human mammary epithelial cells growing in culture and in primary human breast tumors. Clusters of...
Steiner, Joseph P., Hamilton, Gregory S., Ross, Douglas T., Valentine, Heather L., Guo, Hongzhi, Connolly, Maureen A., ...
Although immunosuppressant immunophilin ligands promote neurite outgrowth in vitro, their neurotrophic activities are clearly independent of their immunosuppressive activity. In the present report, a...
Microarrays and molecular markers for tumor classification
Ring, Brian Z, Ross, Douglas T
Human cancers have traditionally been classified according to their tissue of origin, histological characteristics and, to some extent, molecular markers. Clinical studies have associated different...
Gene Expression Patterns in Ovarian Carcinomas
Schaner, Marci E., Ross, Douglas T., Ciaravino, Giuseppe, Sørlie, Therese, Troyanskaya, Olga, Diehn, Maximilian, ...
We used DNA microarrays to characterize the global gene expression patterns in surface epithelial cancers of the ovary. We identified groups of genes that distinguished the clear cell subtype from...
Gusterson, Barry A, Ross, Douglas T, Heath, Victoria J, Stein, Torsten
Recent publications have classified breast cancers on the basis of expression of cytokeratin-5 and -17 at the RNA and protein levels, and demonstrated the importance of these markers in defining...
Predicting the sites of metastases
Ring, Brian Z, Ross, Douglas T
Recent work has identified genes implicated in the tissue tropism of breast-cancer metastasis.
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
Perou, Charles M., Jeffrey, Stefanie S., Van De Rijn, Matt, Rees, Christian A., Eisen, Michael B., Ross, Douglas T., ...
cDNA microarrays and a clustering algorithm were used to identify patterns of gene expression in human mammary epithelial cells growing in culture and in primary human breast tumors. Clusters of...
Steiner, Joseph P., Hamilton, Gregory S., Ross, Douglas T., Valentine, Heather L., Guo, Hongzhi, Connolly, Maureen A., ...
Although immunosuppressant immunophilin ligands promote neurite outgrowth in vitro, their neurotrophic activities are clearly independent of their immunosuppressive activity. In the present report, a...
Microarrays and molecular markers for tumor classification
Ring, Brian Z, Ross, Douglas T
Human cancers have traditionally been classified according to their tissue of origin, histological characteristics and, to some extent, molecular markers. Clinical studies have associated different...
Gene Expression Patterns in Ovarian Carcinomas
Schaner, Marci E., Ross, Douglas T., Ciaravino, Giuseppe, Sørlie, Therese, Troyanskaya, Olga, Diehn, Maximilian, ...
We used DNA microarrays to characterize the global gene expression patterns in surface epithelial cancers of the ovary. We identified groups of genes that distinguished the clear cell subtype from...
Gusterson, Barry A, Ross, Douglas T, Heath, Victoria J, Stein, Torsten
Recent publications have classified breast cancers on the basis of expression of cytokeratin-5 and -17 at the RNA and protein levels, and demonstrated the importance of these markers in defining...
Predicting the sites of metastases
Ring, Brian Z, Ross, Douglas T
Recent work has identified genes implicated in the tissue tropism of breast-cancer metastasis.
Li, Shiyong, Ross, Douglas T., Kadin, Marshall E., Brown, Patrick O., Wasik, Mariusz A.
Using a cDNA microarray, we compared the expression of approximately 8000 genes between two unique, clonally related T cell lines derived from different stages of a progressive T cell lymphoma...