Li, Chi-Ming, Guo, Meirong, Salas, Martha, Schupf, Nicole, Silverman, Wayne, Zigman, Warren B, ...
Abstract Background Down syndrome (DS) is caused by trisomy 21 (+21), but the aberrations in gene expression resulting from this chromosomal aneuploidy are not yet completely understood. Methods We...
Trisomic Pregnancy and Earlier Age at Menopause
Kline, Jennie, Kinney, Ann, Levin, Bruce, Warburton, Dorothy
We tested the hypothesis that the connection between advanced maternal age and autosomal trisomy reflects the diminution of the oocyte pool with age. Because menopause occurs when the number of...
DNA adducts and related biomarkers in populations exposed to environmental carcinogens
Perera, Frederica, Brenner, Diane, Jeffrey, Alan, Mayer, Jack, Tang, Deliang, Warburton, Dorothy, ...
Prevention of environmentally related cancer will be enhanced by the availability of sensitive early warning systems and by improvements in quantitative assessment of human risks. Accordingly, we...
Driscoll, M. Catherine, Lerner, Norma, Anyane-Yeboa, Kwame, Maidman, Jack, Warburton, Dorothy, Schaefer-Rego, Kim, ...
We report here an evaluation of 55 pregnancies at risk for a sickle hemoglobinopathy prenatally diagnosed by restriction-endonuclease analysis, with the endonucleases MstII and HpaI, of amniocyte...
Trisomy Recurrence: A Reconsideration Based on North American Data
Warburton, Dorothy, Dallaire, Louis, Thangavelu, Maya, Ross, Lori, Levin, Bruce, Kline, Jennie
Few reliable data exist concerning the recurrence risk for individual trisomies or the risk for recurrence of trisomy for a different chromosome. We collected records from two sources: (1) prenatal...
Trisomic Pregnancy and Earlier Age at Menopause
Kline, Jennie, Kinney, Ann, Levin, Bruce, Warburton, Dorothy
We tested the hypothesis that the connection between advanced maternal age and autosomal trisomy reflects the diminution of the oocyte pool with age. Because menopause occurs when the number of...
DNA adducts and related biomarkers in populations exposed to environmental carcinogens
Perera, Frederica, Brenner, Diane, Jeffrey, Alan, Mayer, Jack, Tang, Deliang, Warburton, Dorothy, ...
Prevention of environmentally related cancer will be enhanced by the availability of sensitive early warning systems and by improvements in quantitative assessment of human risks. Accordingly, we...
Driscoll, M. Catherine, Lerner, Norma, Anyane-Yeboa, Kwame, Maidman, Jack, Warburton, Dorothy, Schaefer-Rego, Kim, ...
We report here an evaluation of 55 pregnancies at risk for a sickle hemoglobinopathy prenatally diagnosed by restriction-endonuclease analysis, with the endonucleases MstII and HpaI, of amniocyte...