Activation of Polynuclear Aromatic Hydrocarbons to Mutagens by the Marine Ciliate Parauronema acutum
The marine ciliate Parauronema acutum converted 2-aminofluorene and 2-acetylaminofluorene to compounds with mutagenic activity in the Ames Salmonella test. The ciliate, however, did not activate...
Assay Conditions and the Demonstration of Nitroimidazole Resistance in Tritrichomonas foetus
Meingassner, Josef G., Mieth, Hubert, Czok, Rudolf, Lindmark, Donald G., Müller, Miklós
Tritrichomonas foetus KV1, a nitroimidazole-susceptible strain, and KV1/M100, its nitroimidazole-resistant daughter strain, differed markedly in their in vivo susceptibility to metronidazole. In...
MÜller, MiklÓs, Lindmark, Donald G.
[14C]metronidazole used at the chemotherapeutic concentration of 10 μg/ml is taken up rapidly by the anaerobic protozoa Tritrichomonas foetus, Trichomonas vaginalis, and Entamoeba invadens kept...
Antitrichomonad Action, Mutagenicity, and Reduction of Metronidazole and Other Nitroimidazoles
Lindmark, Donald G., Müller, Miklós
Twelve 4- and 5-nitroimidazole derivatives, including metronidazole and two of its metabolites, tinidazole, dimetridazole, and nimorazole, were tested for antitrichomonad action on Tritrichomonas...
Activation of Polynuclear Aromatic Hydrocarbons to Mutagens by the Marine Ciliate Parauronema acutum
The marine ciliate Parauronema acutum converted 2-aminofluorene and 2-acetylaminofluorene to compounds with mutagenic activity in the Ames Salmonella test. The ciliate, however, did not activate...
Assay Conditions and the Demonstration of Nitroimidazole Resistance in Tritrichomonas foetus
Meingassner, Josef G., Mieth, Hubert, Czok, Rudolf, Lindmark, Donald G., Müller, Miklós
Tritrichomonas foetus KV1, a nitroimidazole-susceptible strain, and KV1/M100, its nitroimidazole-resistant daughter strain, differed markedly in their in vivo susceptibility to metronidazole. In...
MÜller, MiklÓs, Lindmark, Donald G.
[14C]metronidazole used at the chemotherapeutic concentration of 10 μg/ml is taken up rapidly by the anaerobic protozoa Tritrichomonas foetus, Trichomonas vaginalis, and Entamoeba invadens kept...
Antitrichomonad Action, Mutagenicity, and Reduction of Metronidazole and Other Nitroimidazoles
Lindmark, Donald G., Müller, Miklós
Twelve 4- and 5-nitroimidazole derivatives, including metronidazole and two of its metabolites, tinidazole, dimetridazole, and nimorazole, were tested for antitrichomonad action on Tritrichomonas...