Dolph Hatfield

The Sep15 Protein Family: Roles in Disulfide Bond Formation and Quality Control in the Endoplasmic Reticulum (2007)

Labunskyy, Vyacheslav M., Hatfield, Dolph, Gladyshev, Vadim N.

Disulfide bonds play an important role in the structure and function of membrane and secretory proteins. The formation of disulfide bonds in the endoplasmic reticulum (ER) of eukaryotic cells is...

malB Region in Escherichia coli K-12: Characterization of New Mutations

Hofnung, Maurice, Hatfield, Dolph, Schwartz, Maxime

Phenotypic characterization and mapping of more than 50 Mal− mutations located in the malB region lead one to divide the site for Mal−λs mutations (formerly called gene malB) in that region,...

Nonsense Mutations in the Maltose A Region of the Genetic Map of Escherichia coli

Hatfield, Dolph, Hofnung, Maurice, Schwartz, Maxime

The isolation of one amber mutation in malQ, one ochre mutation in malP, and seven amber mutations in malT is reported. A study of their phenotypic expressions in the presence of the amber suppressor...

Seryl-tRNA in Mammalian Tissues: Chromatographic Differences in Brain and Liver and a Specific Response to the Codon, UGA

Hatfield, Dolph, Portugal, Franklin H.

Differences in the elution profiles of seryl-tRNAs of beef and of rabbit liver and brain were observed. A species of beef seryl-tRNA obtained by reversed phase column chromatography that responds...

Genetic Analysis of the Maltose A Region in Escherichia coli

Hatfield, Dolph, Hofnung, Maurice, Schwartz, Maxime

The genetic map of the maltose A locus of Escherichia coli contains at least three closely linked genes, malT, malP, and malQ. The order of these genes is established by deletion mapping. MalP and...

Recognition of Nonsense Codons in Mammalian Cells

Hatfield, Dolph

The tritiated trinucleotide UGA was used in a binding assay to detect transfer RNAs that recognize this nonsense codon from calf-liver cells. Acylation of transfer RNA with labeled amino acids and...

malB Region in Escherichia coli K-12: Characterization of New Mutations

Hofnung, Maurice, Hatfield, Dolph, Schwartz, Maxime

Phenotypic characterization and mapping of more than 50 Mal− mutations located in the malB region lead one to divide the site for Mal−λs mutations (formerly called gene malB) in that region,...

Nonsense Mutations in the Maltose A Region of the Genetic Map of Escherichia coli

Hatfield, Dolph, Hofnung, Maurice, Schwartz, Maxime

The isolation of one amber mutation in malQ, one ochre mutation in malP, and seven amber mutations in malT is reported. A study of their phenotypic expressions in the presence of the amber suppressor...

Seryl-tRNA in Mammalian Tissues: Chromatographic Differences in Brain and Liver and a Specific Response to the Codon, UGA

Hatfield, Dolph, Portugal, Franklin H.

Differences in the elution profiles of seryl-tRNAs of beef and of rabbit liver and brain were observed. A species of beef seryl-tRNA obtained by reversed phase column chromatography that responds...

Genetic Analysis of the Maltose A Region in Escherichia coli

Hatfield, Dolph, Hofnung, Maurice, Schwartz, Maxime

The genetic map of the maltose A locus of Escherichia coli contains at least three closely linked genes, malT, malP, and malQ. The order of these genes is established by deletion mapping. MalP and...

Recognition of Nonsense Codons in Mammalian Cells

Hatfield, Dolph

The tritiated trinucleotide UGA was used in a binding assay to detect transfer RNAs that recognize this nonsense codon from calf-liver cells. Acylation of transfer RNA with labeled amino acids and...