Eukaryotic cells contain scores of small nucleolar RNAs (snoRNAs), which are required for maturation of pre-rRNA. Two large snoRNA families exist defined by vital box C/D and box H/ACA motifs. The...
Samarsky, Dmitry A., Ferbeyre, Gerardo, Bertrand, Edouard, Singer, Robert H., Cedergren, Robert, Fournier, Maurille J.
A hammerhead ribozyme has been localized to the yeast nucleolus by using the U3 small nucleolar RNA as a carrier. The hybrid small nucleolar RNA:ribozyme, designated a “snorbozyme,” is...
Functional Mapping of the U3 Small Nucleolar RNA from the Yeast Saccharomyces cerevisiae
Samarsky, Dmitry A., Fournier, Maurille J.
The U3 small nucleolar RNA participates in early events of eukaryotic pre-rRNA cleavage and is essential for formation of 18S rRNA. Using an in vivo system, we have developed a functional map of the...
Samarsky, Dmitry A., Ferbeyre, Gerardo, Bertrand, Edouard, Singer, Robert H., Cedergren, Robert, Fournier, Maurille J.
A hammerhead ribozyme has been localized to the yeast nucleolus by using the U3 small nucleolar RNA as a carrier. The hybrid small nucleolar RNA:ribozyme, designated a “snorbozyme,” is...
Functional Mapping of the U3 Small Nucleolar RNA from the Yeast Saccharomyces cerevisiae
Samarsky, Dmitry A., Fournier, Maurille J.
The U3 small nucleolar RNA participates in early events of eukaryotic pre-rRNA cleavage and is essential for formation of 18S rRNA. Using an in vivo system, we have developed a functional map of the...